Bills vs. Texans Odds & Betting Predictions - November 21, 2025

Bills at Texans

1:15 am • Amazon Prime Video
19 - 23

Bills at Texans Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Bills
7-4
N/A
N/A
N/A
Texans
6-5
N/A
N/A
N/A
location pinFriday 1:15 a.m.
November 21, 2025
NRG StadiumHouston
Bills vs. Texans Expert Picks
Sandy Plashkes
Sandy Plashkes
Last 30d: 125-138-7 (-16.4u)
J.Allen o21.5 Rush Yds (Live)-125
1.25u
Mjaybrod
Mjaybrod
Last 30d: 140-113-0 (+31.7u)
Over 41.5 (Live)+102
1.02u
Stuck 🚨
Stuck 🚨
Last 30d: 54-64-1 (-3.8u)
HOU +7.5 (Live)-115
0.13u
Matt DiLeo
Matt DiLeo
Last 30d: 51-43-5 (+1.1u)
D.Mills o7.5 Rush Yds (Live)-114
1u
Placed pregame
Mjaybrod
Mjaybrod
Last 30d: 140-113-0 (+31.7u)
HOU +6.5 (Live)-110
0.91u
Value
Cam Is Money
Cam Is Money
Last 30d: 118-116-3 (-5.5u)
G.Davis o20.5 Rec Yds-120
0.83u
Nick Giffen
Nick Giffen
Last 30d: 58-73-1 (+11.6u)
HOU +3.5 (1H)-125
0.2u
#Tailing @The_Oddsmaker
HOU +5.5-110
0.5u
HOU +225
0.56u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 204-205-14 (+7.7u)
D.Knox o2.5 Recs+110
0.88u
3.47% ev
Derek Carty
Derek Carty
Last 30d: 12-9-0 (+4.8u)
K.Shakir o41.5 Rec Yds-112
1u
THE BLITZ is forecasting 72.88 receiving yards for Khalil Shakir. The oddsmakers' implied projection is 51.31 receiving yards, so I believe there is some value here. If you take the over, you’d be projected to win 72% of the time resulting in a 37% ROI with expected value of $41.32 (based on a $100 wager). (This play is good down to at least -169.) Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
Collin Wilson
Collin Wilson
Last 30d: 97-78-0 (+11.5u)
HOU +5.5-110
1u
RocketPlays
RocketPlays
Last 30d: 47-112-3 (+1.9u)
G.Davis Anytime TD Scorer Yes+550
0.25u
TD Jackpot
The Degenerates
The Degenerates
Last 30d: 81-84-2 (-8.9u)
BUF u24.5-115
1u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 204-205-14 (+7.7u)
J.Higgins u2.5 Recs+110
0.8u
3.31% ev
Brandon Anderson
Brandon Anderson
Last 30d: 54-144-4 (+11.2u)
HOU +5.5+100
0.5u
I don’t often play these Thursday night games, but this line just feels way off. I make it below a field goal even without Stroud. Houston defense really messed with Allen last time, and Texans have five losses by one score this season, three which would have covered this number. I really think the Texans are live to win outright.
Mjaybrod
Mjaybrod
Last 30d: 140-113-0 (+31.7u)
W.Marks Anytime TD Scorer Yes+115
1u
I am hard
W.Marks 2+ TDs Yes+850
0.25u
Huge woody guy
W.Marks o61.5 Rush Yds-110
0.91u
I got a woody
Scott Rickenbach
Scott Rickenbach
Last 30d: 117-96-0 (+7.5u)
Under 44.5-115
0.87u
Vegas Refund
Vegas Refund
Last 30d: 38-43-1 (-9.3u)
HOU +5.5-108
1u
YBK Picks.com
Last 30d: 42-40-1 (+1.3u)
HOU +5.5-105
1.9u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 204-205-14 (+7.7u)
HOU +140 (1Q)
0.3u
1.92% ev
J.Palmer o2.5 Recs+110
1.6u
7.16% ev
Kenny Ducey
Kenny Ducey
Last 30d: 21-21-1 (-1.2u)
HOU +5.5-110
1u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 204-205-14 (+7.7u)
J.Allen o1.5 Pass TDs+132
1u
5.44% ev
Boomer Betz
Boomer Betz
Last 30d: 210-198-11 (+24.7u)
G.Davis Anytime TD Scorer Yes+550
0.25u
Jackcock Entry
Bet Labs
Bet Labs
Last 30d: 25-26-0 (+2.6u)
Over 44-110
1.1u
Allan Lem
Allan Lem
Last 30d: 172-119-3 (+19.0u)
HOU +3.5 (1H)-122
0.25u
Action Instagram channel best bet - let’s ride 🚀
Capper Central
Capper Central
Last 30d: 90-77-0 (+1.7u)
HOU +5.5+100
1u
Allan Lem
Allan Lem
Last 30d: 172-119-3 (+19.0u)
N.Collins u5.5 Recs+105
0.5u
Tailing @The_Oddsmaker
Sean Koerner
Sean Koerner
Last 30d: 50-35-0 (+7.8u)
N.Collins u5.5 Recs+105
0.53u
Full write up/article in the app
Boomer Betz
Boomer Betz
Last 30d: 210-198-11 (+24.7u)
BUF -5.5-101
1.01u
Px
Brandon Kravitz
Brandon Kravitz
Last 30d: 78-85-4 (-0.1u)
Under 43.5-104
1u
Houston under vs winning teams under Ryans: 17-6. Allen 37-22 to the under on the road.
Sean Koerner
Sean Koerner
Last 30d: 50-35-0 (+7.8u)
K.Lassiter o7.5 Tackles + Ast+383
0.2u
🪜
K.Lassiter o5.5 Tackles + Ast+106
0.5u
On the surface this looks like a pretty fair number for Lassiter. He’s averaging 5.8 tackles a game, but my projections flagged this as a potential eruption spot, and it’s easy to see why. The Texans have an elite defense and rank 3rd in average time of possession, so it’s not too surprising they’ve allowed the 4th fewest plays per game. However, they face a Bills offense that ranks 2nd in time of possession, and I’m projecting the Texans to face more play volume tonight with about +1.4 more completions than their season average and, more importantly, +5.9 more rush attempts. Lassiter is a CB who is heavily involved in run defense and actually leads all cornerbacks in run tackles, three more than the next closest player. This matchup specifically favors him. He’s also faced one of the toughest schedules for a CB, and I project him for +5.8 more tackles on the season (+0.58 per game) if he had faced a league-average slate. The Bills provide the 2nd most tackle opportunities to CBs, making this by far his best matchup of the season. The only two teams he’s faced with above-average CB tackle opportunity rates were the Rams (he had 9) and the Broncos (he had 10, and yes, if you remember, I was on his over in that game too). This is the perfect spot for him to rack up 6+ tackles. I���m projecting him closer to 6.7 with around a 65% chance he clears 5.5, and we are also getting plus odds. I’m also going to ladder this. Since the market moves too fast for me to grab multiple rungs, I usually need to pick the one offering the most value. I’m going with 8+ at +383, which I project closer to +180. If you want to sprinkle on any other alts, go for it, because every single one is showing value until the market inevitably moves within minutes.
💰🦡 Jake
💰🦡 Jake
Last 30d: 85-110-6 (-16.7u)
N.Chubb o20.5 Rush Yds-115
1.15u
K.Shakir Anytime TD Scorer Yes+310
0.5u
Grant Neiffer
Grant Neiffer
Last 30d: 46-83-10 (+4.1u)
T.Shavers 80+ Receiving Yards Yes+1200
0.1u
T.Shavers 50+ Receiving Yards Yes+400
0.1u
T.Shavers 60+ Receiving Yards Yes+600
0.1u
T.Shavers 70+ Receiving Yards Yes+850
0.1u
T.Shavers 30+ Receiving Yards Yes+146
0.1u
T.Shavers 40+ Receiving Yards Yes+240
0.1u
K.Shakir Anytime TD Scorer Yes+310
0.25u
T.Shavers Anytime TD Scorer Yes+500
0.25u
T.Shavers o21.5 Rec Yds-114
0.57u
Markus Markets
Markus Markets
Last 30d: 48-49-3 (+5.6u)
K.Shakir o4.5 Recs-117
1.28u
Sandy Plashkes
Sandy Plashkes
Last 30d: 125-138-7 (-16.4u)
K.Shakir o42.5 Rec Yds-112
1.5u
@RoyalsProps model play
Royals Props
Royals Props
Last 30d: 35-40-3 (-9.9u)
K.Shakir o42.5 Rec Yds-110
1u
Kyle Murray
Kyle Murray
Last 30d: 85-89-6 (-9.3u)
W.Marks o10.5 Rec Yds-115
1.15u
Moneyline Hacks
Moneyline Hacks
Last 30d: 151-152-3 (+43.5u)
K.Shakir o4.5 Recs-130
0.77u
🚨Free analysis & VIP Picks can be found on our Discord. Link: https://discord.gg/JrzjtqdVfA 🔥 50% OFF 1-MONTH VIP!! 🔥 Get full access to every bet, model, and tools from the Moneyline Hacks team. ⬇️⬇️ 🌐 https://dubclub.win/MoneylineHacks/ 🎙️Fade the Noise PODCAST - Subscribe!✅ https://www.youtube.com/@FadetheNoise 💎FREE TRIAL!!💎 (COPY & PASTE LINK) https://linktr.ee/moneylinehacks
Gilles Gallant
Gilles Gallant
Last 30d: 23-75-0 (-7.2u)
D.Mills Anytime TD Scorer Yes+1400
0.25u
J.Higgins Anytime TD Scorer Yes+525
2.63u
D.Knox Anytime TD Scorer Yes+400
0.5u
💰🦡 Jake
💰🦡 Jake
Last 30d: 85-110-6 (-16.7u)
BUF -3.5 (1H)+100
1u
Under 43.5-105
1u
Roger Goodell
Roger Goodell
Last 30d: 40-45-0 (-0.3u)
J.Higgins o26.5 Rec Yds-118
0.42u
Sean Koerner
Sean Koerner
Last 30d: 50-35-0 (+7.8u)
HOU +3.5 (1H)-115
0.5u
Full write up will be in my TNF betting preview. Out first thing tomorrow
Grant Neiffer
Grant Neiffer
Last 30d: 46-83-10 (+4.1u)
K.Coleman 80+ Receiving Yards Yes+1500
0.1u
K.Coleman 40+ Receiving Yards Yes+270
0.1u
K.Coleman 50+ Receiving Yards Yes+475
0.1u
K.Coleman 60+ Receiving Yards Yes+680
0.1u
K.Coleman 70+ Receiving Yards Yes+990
0.1u
K.Coleman o21.5 Rec Yds-114
0.57u
K.Coleman 30+ Receiving Yards Yes+154
0.2u
Roger Goodell
Roger Goodell
Last 30d: 40-45-0 (-0.3u)
HOU +6-105
0.95u
Picks Office
Picks Office
Last 30d: 218-182-4 (+20.5u)
BUF -6-105
1u
Link in Bio for early access
Cam Is Money
Cam Is Money
Last 30d: 118-116-3 (-5.5u)
J.Higgins o27.5 Rec Yds-118
0.85u
Will Brinson
Will Brinson
Last 30d: 21-25-3 (-3.9u)
J.Allen Anytime TD Scorer Yes-112
1.12u
Great price here. NINE rushing tds from Week 10-Week 16 last year and he’s going to start pouring it on again as the Bills push for the AFC East.
FTN Fantasy
FTN Fantasy
Last 30d: 115-138-2 (-32.7u)
HOU +3.5-110
0.91u

Bills vs. Texans Previews & Analysis

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Bills vs. Texans Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Bills vs. Texans Public Betting Percentages

Away Logo

Bills

Public

50%

Bets%

50%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Texans
5-64-21-44-31-3
Bills
5-63-32-33-62-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Texans
3-81-52-32-51-3
Bills
5-64-21-44-51-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Texans
6-5N/AN/A5-21-3
Bills
7-4N/AN/A5-42-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 16th@TENW 16-13---
Nov 9thJACW 36-29---
Nov 2ndDENL 15-18---
Oct 26thSFW 26-15---
Oct 21st@SEAL 19-27---

Texans vs. Bills Injury Updates

Texans Injuries

  • Joe Mixon
    RB

    Mixon is out with knee

    Out

  • Harrison Bryant
    TE

    Bryant is out with neck

    Out

  • C.J. Stroud
    QB

    Stroud is out with concussion

    Out

  • Tank Dell
    WR

    Dell is out with knee

    Out

Bills Injuries

  • Curtis Samuel
    WR

    Samuel is out with elbow

    Out

  • Mitch Wishnowsky
    P

    Wishnowsky is out with back

    Out

  • Mecole Hardman
    WR

    Hardman is out with calf

    Out

  • Tyler Bass
    K

    Bass is out with hip

    Out

  • Dalton Kincaid
    TE

    Kincaid is out with hamstring

    Out

Team Stats
326
Total Yards
261
66
Total Plays
56
4.9
Yards Per Play
4.7
253
YDS
153
24/34
Comps/Atts
16/30
4.357
YPA
5.1
0/2
TDs/INTs
2/0
8/70
Sacks/Yards
0/0
143
Rush Yards
108
24
Attempts
26
5.958
YPC
4.154
1
TDs
0

Turnovers

1
Fumbles Lost
0
2
Interceptions
0

Efficiency

0/2 0%
Redzone
2/4 50%
5/16 0%
3rd Down
2/12 0%
3/5 0%
4th Down
1/1 0%

First Downs

14
Total
15
9
Pass
7
5
Rush
6
0
Penalty
2
6/54
Penalties/Yards
5/40
32:22
Possession
27:38

Bills vs. Texans Odds Comparison

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Bills at Texans Team Totals

MatchupOverUnder
Bills
7-4
N/A
N/A
Texans
6-5
N/A
N/A