49ers vs. Texans Odds & Betting Predictions - October 26, 2025
49ers at Texans
5:00 pm • FOX49ers at Texans Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 49ers 4-2 | -1.5 | -1.5-108 | o45.5-115 | -125 |
 Texans 2-3 | u45.5 | +1.5-112 | u45.5-105 | +105 |
NRG StadiumHouston
49ers vs. Texans Props
Prop Projections
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Prop Odds Comparison
Line Movement Tracker
49ers vs. Texans Public Betting Percentages
Betting Trends
- Texans are 2-3 in their last 5 games.
- Texans are 2-3 in their last 5 games against the spread
- Texans are 1-2 in their road games against the spread
- The totals have gone OVER in 1 of Texans' last 5 games
- The totals have gone OVER in 0 of Texans' 2 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
49ers vs. Texans Injury Updates
49ers Injuries
- George KittleTE
Kittle is questionable with hamstring
Questionable
- Brandon AiyukWR
Aiyuk is out with knee
Out
- Jauan JenningsWR
Jennings is questionable with ribs
Questionable
- Brock PurdyQB
Purdy is questionable with toe
Questionable
- Ricky PearsallWR
Pearsall is questionable with knee
Questionable
- Jacob CowingWR
Cowing is out with hamstring
Out
- Jordan WatkinsWR
Watkins is doubtful with ankle
Doubtful
- Jordan JamesRB
James is doubtful with finger
Doubtful
Texans Injuries
- Joe MixonRB
Mixon is out with knee
Out
- Tank DellWR
Dell is out with knee
Out
- Cade StoverTE
Stover is out with foot
Out
Player Stats
- passing yards
C.J. Stroud1076pyds - passing touchdownsC.J. Stroud8ptd
- rushing yards
Nick Chubb249ryds - rushing touchdownsNick Chubb2rtd
Depth Charts
| Starter | 2ND | 3RD | 4TH | |||
|---|---|---|---|---|---|---|
| QB | C.J. Stroud | Davis Mills | Graham Mertz | |||
| RB | Joe Mixon | Nick Chubb | Dameon Pierce | Dare Ogunbowale | Woody Marks | Jawhar Jordan |
| WR | Christian Kirk | Jaylin Noel | Braxton Berrios | |||
| TE | Dalton Schultz | Cade Stover | Harrison Bryant | Luke Lachey | ||
| LT | Aireontae Ersery | |||||
| LG | Laken Tomlinson | |||||
| C | Jake Andrews | Jarrett Patterson | Eli Cox | |||
| RG | Ed Ingram | Juice Scruggs | ||||
| RT | Tytus Howard | Blake Fisher | Trent Brown | |||
| LDE | Will Anderson | Darrell Taylor | Derek Barnett | |||
| RDE | Danielle Hunter | Denico Autry | Dylan Horton | Solomon Byrd | ||
| WLB | Henry To'oTo'o | Christian Harris | Jake Hansen | Jackson Woodard | ||
| MLB | Azeez Al-Shaair | E.J. Speed | Jamal Hill | |||
| LCB | Derek Stingley | Jaylin Smith | Tremon Smith | |||
| SS | M.J. Stewart | Jaylen Reed | Jalen Mills | |||
| FS | Calen Bullock | Jimmie Ward | ||||
| RCB | Kamari Lassiter | D'Angelo Ross | Damon Arnette | |||
| P | Tommy Townsend | |||||
| H | Tommy Townsend | |||||
| PR | Braxton Berrios | Jaylin Noel | Christian Kirk | Jawhar Jordan | ||
| KR | Dameon Pierce | Braxton Berrios | Woody Marks | Jaylin Noel | ||
| LS | Austin Brinkman | |||||
| LWR | Nico Collins | Xavier Hutchinson | Quintez Cephus | |||
| FB | Jakob Johnson | British Brooks | ||||
| NT | Sheldon Rankins | Mario Edwards | Tommy Togiai | Haggai Ndubuisi | ||
| DT | Tim Settle | Folorunso Fatukasi | Kurt Hinish | Junior Tafuna | ||
| NB | Jalen Pitre | Myles Bryant | Alijah Huzzie | |||
| K | Ka'imi Fairbairn | |||||
| RWR | Jayden Higgins | Tank Dell | Justin Watson |
Team Stats
1749
YDS
991
161/241
Comps/Atts
104/148
7.627
YPA
7.426
10/7
TDs/INTs
8/3
13/89
Sacks/Yards
12/108
49ers vs. Texans Odds Comparison
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49ers at Texans Team Totals
MatchupOverUnder | ||
|---|---|---|
49ers 4-2 | N/A | N/A |
Texans 2-3 | N/A | N/A |