 Ducks | Cam Fowler | D | Questionable | Head | Fowler is questionable with head | May 4 |
| Ducks | Jakob Silfverberg | F | Out for season | Hip | Silfverberg is out for season with hip | Apr 23 |
| Ducks | Hampus Lindholm | D | Out | Wrist | Lindholm is out with wrist | Mar 5 |
| Ducks | Adam Henrique | F | Out | COVID Protocols | Henrique is out with covid protocols | Apr 27 |
| Ducks | Andy Welinski | D | Out | Lower Body | Welinski is out with lower body | Apr 29 |
| Ducks | Sonny Milano | F | Out | Undisclosed | Milano is out with undisclosed | Mar 5 |
| Ducks | Carter Rowney | F | Out | Knee | Rowney is out with knee | Mar 19 |
 Coyotes | Antti Raanta | G | Out | Upper Body | Raanta is out with upper body | Apr 26 |
| Coyotes | Tyler Pitlick | F | Out | Lower Body | Pitlick is out with lower body | Apr 20 |
| Coyotes | Nick Schmaltz | F | Questionable | Head | Schmaltz is questionable with head | May 4 |
| Coyotes | Jordan Gross | D | Out | Lower Body | Gross is out with lower body | Apr 13 |
 Bruins | Mike Reilly | D | Out | Undisclosed | Reilly is out with undisclosed | May 3 |
| Bruins | John Moore | D | Out for season | Lower Body | Moore is out for season with lower body | Mar 27 |
| Bruins | Ondrej Kase | F | Out | Upper Body | Kase is out with upper body | Jan 18 |
 Sabres | Jake McCabe | D | Out for season | Knee | McCabe is out for season with knee | Feb 23 |
| Sabres | Jack Eichel | F | Out for season | Neck | Jack Eichel (neck) will miss remainder of the season | Apr 14 |
| Sabres | Zemgus Girgensons | F | Out for season | Hamstring | Girgensons is out for season with hamstring | Apr 20 |
| Sabres | Sam Reinhart | F | Questionable | Undisclosed | Reinhart is questionable with undisclosed | Feb 15 |
| Sabres | Carter Hutton | G | Out for season | Lower Body | Hutton is out for season with lower body | May 4 |
| Sabres | Riley Sheahan | F | Out | Upper Body | Sheahan is out with upper body | Apr 17 |
| Sabres | Kyle Okposo | F | Out for season | Face | Okposo is out for season with face | Apr 17 |
| Sabres | Dustin Tokarski | G | Out for season | Personal | Tokarski is out for season with personal | May 4 |
| Sabres | Linus Ullmark | G | Out | Lower Body | Ullmark is out with lower body | Apr 15 |
| Sabres | Ukko-Pekka Luukkonen | G | Out for season | Lower Body | Luukkonen is out for season with lower body | May 4 |
 Flames | Sean Monahan | F | Doubtful | Lower Body | Monahan is doubtful with lower body | Feb 21 |
| Flames | Noah Hanifin | D | Out for season | Shoulder | Hanifin is out for season with shoulder | Apr 27 |
| Flames | Joakim Nordstrom | F | Probable | Lower Body | Nordstrom is probable with lower body | Mar 26 |
| Flames | Josh Leivo | F | Out | COVID Protocols | Leivo is out with covid protocols | Apr 23 |
 Hurricanes | Jordan Martinook | F | Out | Lower Body | Martinook is out with lower body | Apr 23 |
| Hurricanes | Jake Gardiner | D | Questionable | Upper Body | Gardiner is questionable with upper body | Mar 8 |
| Hurricanes | Cedric Paquette | F | Questionable | Undisclosed | Paquette is questionable with undisclosed | May 2 |
| Hurricanes | Vincent Trocheck | F | Probable | Upper Body | Vincent Trocheck (upper body) upgraded to probable Tuesday at Chicago | Mar 30 |
| Hurricanes | Brady Skjei | D | Probable | Undisclosed | Skjei is probable with undisclosed | May 4 |
| Hurricanes | Martin Necas | F | Probable | Undisclosed | Necas is probable with undisclosed | Feb 14 |
 Blackhawks | Jonathan Toews | F | Out for season | Undisclosed | Toews is out for season with undisclosed | Apr 22 |
| Blackhawks | Calvin de Haan | D | Out | Hip | de Haan is out with hip | Apr 23 |
| Blackhawks | Ryan Carpenter | F | Out | Concussion | Carpenter is out with concussion | Apr 26 |
| Blackhawks | Alexander Nylander | F | Out | Knee | Nylander is out with knee | Dec 23 |
| Blackhawks | Wyatt Kalynuk | D | Questionable | Hip | Kalynuk is questionable with hip | Apr 21 |
| Blackhawks | Adam Boqvist | D | Out for season | Wrist | Boqvist is out for season with wrist | Apr 28 |
 Avalanche | Erik Johnson | D | Out for season | Upper Body | Johnson is out for season with upper body | Apr 10 |
| Avalanche | Devan Dubnyk | G | Out | Illness | Dubnyk is out with illness | May 4 |
| Avalanche | Matt Calvert | F | Out | Undisclosed | Calvert is out with undisclosed | Mar 25 |
| Avalanche | Brandon Saad | F | Out | Lower Body | Saad is out with lower body | Apr 26 |
| Avalanche | J.T. Compher | F | Probable | Upper Body | Compher is probable with upper body | Mar 17 |
| Avalanche | Samuel Girard | D | Questionable | Undisclosed | Girard is questionable with undisclosed | May 2 |
| Avalanche | Pavel Francouz | G | Out for season | Lower Body | Francouz is out for season with lower body | Apr 10 |
| Avalanche | Logan O'Connor | F | Questionable | Lower Body | O'Connor is questionable with lower body | Apr 22 |
| Avalanche | Bowen Byram | D | Out | Upper Body | Byram is out with upper body | Apr 22 |
 Blue Jackets | Gustav Nyquist | F | Out for season | Shoulder | Nyquist is out for season with shoulder | Apr 17 |
| Blue Jackets | Joonas Korpisalo | G | Out | Lower Body | Korpisalo is out with lower body | Apr 27 |
| Blue Jackets | Zach Werenski | D | Out for season | Abdominal | Zach Werenski (abdominal) will miss remainder of the season | Apr 9 |
| Blue Jackets | Matiss Kivlenieks | G | Out | Lower Body | Kivlenieks is out with lower body | Feb 13 |
 Stars | Andrew Cogliano | F | Questionable | Illness | Cogliano is questionable with illness | Mar 21 |
| Stars | Ben Bishop | G | Out for season | Knee | Ben Bishop (knee) will miss remainder of the season | Apr 14 |
| Stars | Jason Dickinson | F | Out | Lower Body | Dickinson is out with lower body | May 3 |
| Stars | Alexander Radulov | F | Out for season | Lower Body | Alexander Radulov (lower body) will miss remainder of the season | Apr 14 |
 Red Wings | Bobby Ryan | F | Out for season | Upper Body | Ryan is out for season with upper body | Apr 9 |
| Red Wings | Robby Fabbri | F | Out | Upper Body | Fabbri is out with upper body | Apr 13 |
| Red Wings | Luke Glendening | F | Probable | Upper Body | Glendening is probable with upper body | Feb 13 |
| Red Wings | Dylan Larkin | F | Out for season | Upper Body | Dylan Larkin (upper body) will miss remainder of the season | Apr 23 |
| Red Wings | Frans Nielsen | F | Questionable | Undisclosed | Nielsen is questionable with undisclosed | Apr 18 |
| Red Wings | Tyler Bertuzzi | F | Out for season | Upper Body | Bertuzzi is out for season with upper body | Apr 22 |
 Oilers | Zack Kassian | F | Out | Lower Body | Kassian is out with lower body | Apr 27 |
| Oilers | Kris Russell | D | Questionable | Lower Body | Russell is questionable with lower body | Apr 30 |
| Oilers | James Neal | F | Probable | Undisclosed | Neal is probable with undisclosed | Mar 4 |
| Oilers | Devin Shore | F | Out | Undisclosed | Shore is out with undisclosed | May 3 |
| Oilers | Slater Koekkoek | D | Out | Collarbone | Koekkoek is out with collarbone | Feb 21 |
| Oilers | Evan Bouchard | D | Probable | Back | Bouchard is probable with back | Feb 2 |
| Oilers | Dominik Kahun | F | Out | Undisclosed | Kahun is out with undisclosed | Mar 4 |
| Oilers | Joakim Nygard | F | Out | Hand | Nygard is out with hand | Apr 23 |
 Panthers | Sam Bennett | F | Out | Upper Body | Bennett is out with upper body | May 4 |
| Panthers | Aaron Ekblad | D | Out for season | Leg | Ekblad is out for season with leg | Mar 30 |
| Panthers | Chris Driedger | G | Doubtful | Lower Body | Driedger is doubtful with lower body | Apr 27 |
| Panthers | Lucas Wallmark | F | Out | COVID Protocols | Wallmark is out with covid protocols | Jan 27 |
| Panthers | Markus Nutivaara | D | Out | Upper Body | Nutivaara is out with upper body | Mar 5 |
| Panthers | Carter Verhaeghe | F | Out | Upper Body | Verhaeghe is out with upper body | Apr 13 |
 Kings | Jonathan Quick | G | Questionable | Upper Body | Quick is questionable with upper body | May 4 |
| Kings | Olli Maatta | D | Out | Upper Body | Maatta is out with upper body | Mar 22 |
| Kings | Blake Lizotte | F | Out | Upper Body | Lizotte is out with upper body | May 1 |
 Wild | Marco Rossi | F | Out for season | Illness | Rossi is out for season with illness | Mar 6 |
 Canadiens | Tomas Tatar | F | Out | Lower Body | Tatar is out with lower body | Apr 29 |
| Canadiens | Paul Byron | F | Out | Lower Body | Byron is out with lower body | Apr 27 |
| Canadiens | Carey Price | G | Out | Concussion | Carey Price (concussion) will miss at least 1 week | Apr 20 |
| Canadiens | Jonathan Drouin | F | Questionable | Illness | Drouin is questionable with illness | Apr 26 |
| Canadiens | Josh Anderson | F | Probable | Lower Body | Anderson is probable with lower body | Mar 6 |
 Predators | Luca Sbisa | D | Out | Upper Body | Sbisa is out with upper body | Jan 25 |
| Predators | Mattias Ekholm | D | Probable | Undisclosed | Ekholm is probable with undisclosed | Feb 27 |
| Predators | Viktor Arvidsson | F | Out | Undisclosed | Arvidsson is out with undisclosed | May 4 |
| Predators | Mark Borowiecki | D | Probable | Upper Body | Borowiecki is probable with upper body | Mar 28 |
| Predators | Colton Sissons | F | Out | Upper Body | Sissons is out with upper body | May 4 |
| Predators | Mathieu Olivier | F | Out | Lower Body | Olivier is out with lower body | Apr 9 |
| Predators | Dante Fabbro | D | Questionable | Upper Body | Fabbro is questionable with upper body | Apr 30 |
 Devils | Aaron Dell | G | Out | COVID Protocols | Dell is out with covid protocols | Jan 28 |
| Devils | Matt Tennyson | D | Out | Lower Body | Tennyson is out with lower body | Apr 29 |
| Devils | Andreas Johnsson | F | Out | Undisclosed | Johnsson is out with undisclosed | Apr 30 |
| Devils | Miles Wood | F | Probable | Illness | Wood is probable with illness | Feb 25 |
 Islanders | Jean-Gabriel Pageau | F | Out | Undisclosed | Pageau is out with undisclosed | May 4 |
| Islanders | Anders Lee | F | Out for season | Lower Body | Lee is out for season with lower body | Mar 17 |
| Islanders | Mathew Barzal | F | Out | Undisclosed | Mathew Barzal (undisclosed) is out Tuesday at Buffalo | May 4 |
 Rangers | Artemi Panarin | F | Doubtful | Lower Body | Panarin is doubtful with lower body | May 4 |
| Rangers | Chris Kreider | F | Out | Lower Body | Kreider is out with lower body | May 3 |
| Rangers | Jacob Trouba | D | Out for season | Upper Body | Trouba is out for season with upper body | May 4 |
| Rangers | Jack Johnson | D | Out | Hernia | Johnson is out with hernia | Mar 20 |
| Rangers | Ryan Lindgren | D | Out for season | Upper Body | Lindgren is out for season with upper body | May 4 |
 Senators | Austin Watson | F | Out for season | Hand | Watson is out for season with hand | Apr 27 |
| Senators | Derek Stepan | F | Out for season | Upper Body | Stepan is out for season with upper body | Mar 2 |
| Senators | Matt Murray | G | Out | Lower Body | Murray is out with lower body | Apr 26 |
| Senators | Micheal Haley | F | Out for season | Groin | Haley is out for season with groin | Apr 2 |
| Senators | Thomas Chabot | D | Out for season | Upper Body | Thomas Chabot (upper body) will likely miss remainder of the season | May 4 |
| Senators | Josh Brown | D | Out for season | Undisclosed | Brown is out for season with undisclosed | May 4 |
| Senators | Anton Forsberg | G | Out | Lower Body | Forsberg is out with lower body | Apr 26 |
| Senators | Joey Daccord | G | Out | Leg | Daccord is out with leg | Mar 18 |
 Flyers | Sean Couturier | F | Probable | Hip | Sean Couturier (hip) upgraded to Probable Monday vs. NY Islanders | Mar 22 |
| Flyers | Carter Hart | G | Out | Knee | Hart is out with knee | Apr 22 |
| Flyers | Tanner Laczynski | F | Out for season | Hip | Laczynski is out for season with hip | Apr 27 |
| Flyers | Morgan Frost | F | Out for season | Shoulder | Frost is out for season with shoulder | Feb 19 |
 Penguins | Kasperi Kapanen | F | Probable | Lower Body | Kapanen is probable with lower body | Apr 22 |
| Penguins | Brian Dumoulin | D | Probable | Lower Body | Dumoulin is probable with lower body | Mar 6 |
| Penguins | Evan Rodrigues | F | Questionable | Ankle | Rodrigues is questionable with ankle | Apr 30 |
| Penguins | Brandon Tanev | F | Out | Upper Body | Tanev is out with upper body | May 4 |
| Penguins | Michael Matheson | D | Out | Face | Matheson is out with face | May 4 |
| Penguins | Casey DeSmith | G | Out | Lower Body | DeSmith is out with lower body | May 4 |
| Penguins | Zachary Aston-Reese | F | Probable | Shoulder | Aston-Reese is probable with shoulder | Feb 11 |
 Sharks | Matt Nieto | F | Out | Lower Body | Nieto is out with lower body | Mar 28 |
| Sharks | Joachim Blichfeld | F | Out | Concussion | Blichfeld is out with concussion | May 4 |
| Sharks | Timo Meier | F | Probable | Lower Body | Meier is probable with lower body | Mar 11 |
 Blues | Carl Gunnarsson | D | Out | Lower Body | Gunnarsson is out with lower body | Feb 23 |
| Blues | Jordan Kyrou | F | Out | Illness | Kyrou is out with illness | Apr 17 |
| Blues | Vince Dunn | D | Out | Upper Body | Dunn is out with upper body | Apr 26 |
| Blues | Oskar Sundqvist | F | Out | Leg | Sundqvist is out with leg | Mar 20 |
 Lightning | Steven Stamkos | F | Out | Lower Body | Steven Stamkos (lower body) is out Saturday at Nashville | Apr 10 |
| Lightning | Jan Rutta | D | Out | Lower Body | Rutta is out with lower body | Mar 31 |
 Maple Leafs | Ben Hutton | D | Out | COVID Protocols | Hutton is out with covid protocols | Mar 23 |
| Maple Leafs | Frederik Andersen | G | Questionable | Lower Body | Andersen is questionable with lower body | Mar 21 |
| Maple Leafs | Jason Spezza | F | Out | Coach's decision | Spezza is out with coach's decision | Jan 25 |
| Maple Leafs | Zach Bogosian | D | Out | Shoulder | Bogosian is out with shoulder | Apr 23 |
| Maple Leafs | Riley Nash | F | Out | Knee | Nash is out with knee | Apr 9 |
| Maple Leafs | Nick Foligno | F | Questionable | Upper Body | Foligno is questionable with upper body | May 4 |
| Maple Leafs | Nic Petan | F | Out | Undisclosed | Petan is out with undisclosed | Mar 6 |
| Maple Leafs | Justin Holl | D | Out | Face | Holl is out with face | May 4 |
 Canucks | Brandon Sutter | F | Out | Upper Body | Sutter is out with upper body | May 3 |
| Canucks | Micheal Ferland | F | Out | Head | Ferland is out with head | Jan 13 |
| Canucks | Antoine Roussel | F | Out | Lower Body | Roussel is out with lower body | Apr 22 |
| Canucks | Justin Bailey | F | Questionable | Upper Body | Bailey is questionable with upper body | Feb 12 |
| Canucks | Tyler Motte | F | Out | Undisclosed | Motte is out with undisclosed | May 4 |
| Canucks | Elias Pettersson | F | Out | Upper Body | Elias Pettersson (upper body) is out Saturday vs. Toronto | Mar 6 |
| Canucks | Marc Michaelis | F | Out | Upper Body | Michaelis is out with upper body | May 3 |
 Golden Knights | Brayden McNabb | D | Doubtful | Lower Body | McNabb is doubtful with lower body | Mar 9 |
| Golden Knights | Alex Pietrangelo | D | Probable | Undisclosed | Pietrangelo is probable with undisclosed | Mar 31 |
| Golden Knights | Ryan Reaves | F | Out | Undisclosed | Reaves is out with undisclosed | Apr 13 |
| Golden Knights | Max Pacioretty | F | Questionable | Undisclosed | Pacioretty is questionable with undisclosed | May 4 |
| Golden Knights | Tomas Nosek | F | Out | Undisclosed | Nosek is out with undisclosed | Apr 27 |
| Golden Knights | Patrick Brown | F | Out | Undisclosed | Brown is out with undisclosed | Apr 5 |
 Capitals | Evgeny Kuznetsov | F | Out | COVID Protocols | Kuznetsov is out with covid protocols | May 4 |
| Capitals | Tom Wilson | F | Out | Suspension | Wilson is out with suspension | Mar 7 |
| Capitals | Lars Eller | F | Questionable | Lower Body | Eller is questionable with lower body | Mar 30 |
| Capitals | Michal Kempny | D | Out | Achilles | Kempny is out with achilles | Jan 11 |
| Capitals | Brian Pinho | F | Out | Undisclosed | Pinho is out with undisclosed | Feb 19 |
 Jets | Jordie Benn | D | Probable | Undisclosed | Benn is probable with undisclosed | Mar 10 |
| Jets | Nikolaj Ehlers | F | Out | Upper Body | Ehlers is out with upper body | Apr 26 |
| Jets | Nathan Beaulieu | D | Out for season | Upper Body | Beaulieu is out for season with upper body | Apr 2 |