San Francisco 49ers Odds
49ers Injuries
All NFL Injuries- Trent WilliamsT
Williams is out with ankle
Out
- Christian McCaffreyRB
McCaffrey is out with knee
Out
- George KittleTE
Kittle is questionable with ankle
Questionable
- George OdumS
Odum is out with knee
Out
- Greg JosephK
Joseph is out with abdomen
Out
- Kevin GivensDE
Givens is questionable with groin
Questionable
- Andre DillardOL
Dillard is questionable with concussion
Questionable
- Mitch WishnowskyP
Wishnowsky is out with back
Out
- Brandon AiyukWR
Aiyuk is out with leg
Out
- Colton McKivitzOL
McKivitz is questionable with knee
Questionable
- Ben BartchOL
Bartch is out with ankle
Out
- Deommodore LenoirDB
Lenoir is out with shoulder
Out
- Spencer BurfordOL
Burford is out with calf
Out
- Brock PurdyQB
Purdy is out with elbow
Out
- Ji'Ayir BrownS
Brown is questionable with ankle
Questionable
- Robert BealDE
Beal is out with ankle
Out
- Darrell LuterCB
Luter is doubtful with pelvis
Doubtful
- Renardo GreenDB
Green is questionable with neck
Questionable
49ers 2025 Schedule & Betting Odds
Depth Chart
| Starter | 2ND | 3RD | 4TH | |
|---|---|---|---|---|
| QB | Brock Purdy | Joshua Dobbs | Brandon Allen | Tanner Mordecai |
| RB | Christian McCaffrey | Elijah Mitchell | Jordan Mason | Patrick Taylor |
| WR | Jauan Jennings | Jacob Cowing | Trent Taylor | |
| TE | George Kittle | Eric Saubert | Brayden Willis | Jake Tonges |
| LT | Jaylon Moore | Sebastian Gutierrez | Isaac Alarcon | |
| LG | Aaron Banks | Spencer Burford | Nick Zakelj | |
| C | Jake Brendel | Ben Bartch | Drake Nugent | |
| RG | Dominick Puni | Jon Feliciano | ||
| RT | Colton McKivitz | |||
| LDE | Nick Bosa | Robert Beal | Alex Barrett | Jonathan Garvin |
| LDT | Maliek Collins | Kevin Givens | ||
| RDT | Javon Hargrave | Jordan Elliott | Kalia Davis | Evan Anderson |
| RDE | Leonard Floyd | Yetur Gross-Matos | Sam Okuayinonu | |
| WLB | Dee Winters | |||
| MLB | Fred Warner | Curtis Robinson | Tatum Bethune | |
| SLB | De'Vondre Campbell | Demetrius Flannigan-Fowles | Jalen Graham | |
| LCB | Charvarius Ward | |||
| SS | Malik Mustapha | |||
| FS | Ji'Ayir Brown | George Odum | Jaylen Mahoney | |
| RCB | Isaac Yiadom | Rock Ya-Sin | Darrell Luter | |
| P | Mitch Wishnowsky | |||
| H | Mitch Wishnowsky | |||
| PR | Trent Taylor | Ricky Pearsall | ||
| KR | Ricky Pearsall | Trent Taylor | ||
| LS | Taybor Pepper | |||
| K | Jake Moody | |||
| LWR | Brandon Aiyuk | Ricky Pearsall | Chris Conley | |
| NB | Deommodore Lenoir | Renardo Green | Chase Lucas | |
| FB | Kyle Juszczyk | |||
| RWR | Deebo Samuel |
San Francisco 49ers Player Stats
- passing yards
--pyds - passing touchdowns--ptd
- rushing yards--ryds
- rushing touchdowns--rtd
San Francisco 49ers Odds, Bet Types, and Team History
The 49ers reached the Super Bowl last year behind the back of Brock Purdy. This year, the 49ers return all 11 starters on offense, including Christian McCaffrey and Purdy.
Meanwhile, the 49ers' defense was stellar as usual and returns a majority of their key pieces.
Will San Francisco finally break through and get the job done under Kyle Shanahan? Or will they continue to just miss that elusive Super Bowl championship?
Weather for 49ers Games
Keep track of the conditions for 49ers games by checking out our NFL weather page.
How to Bet on the SF 49ers
Sports betting in California still isn't legal after two props failed to pass. But, if you wish to place bets on the 49er from one of the states where sports betting is legal, make sure you use the BetMGM promo code.
PrizePicks Promo Code
PrizePicks is a Daily Fantasy Sports provider that began operating in late 2018. The game can be explained in one simple statement; choose over/under props for your favorite players to win cash. Californians can play PrizePicks until online sports betting becomes legalized by downloading the app.