Titans vs. Cardinals Odds & Betting Predictions - October 5, 2025

Titans at Cardinals

8:05 pm • CBS
22 - 21

Titans at Cardinals Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Titans
1-5
+7
+7.5-110
o41.5-110
+330
Cardinals
2-4
u46.5
-7.5-110
u41.5-110
-420
location pinSunday 8:05 p.m.
October 05, 2025
State Farm StadiumGlendale
Titans vs. Cardinals Expert Picks
Chris Raybon
Chris Raybon
Last 30d: 28-35-1 (+9.4u)
Z.Knight Anytime TD Scorer Yes+700
1.75u
Gilles Gallant
Gilles Gallant
Last 30d: 23-83-0 (-18.5u)
M.Carter Anytime TD Scorer Yes+150
0.75u
#Tailing @ChrisRaybon
Chris Raybon
Chris Raybon
Last 30d: 28-35-1 (+9.4u)
M.Carter Anytime TD Scorer Yes+150
1.5u
Cam Is Money
Cam Is Money
Last 30d: 59-90-3 (-28.7u)
M.Harrison o52.5 Rec Yds-130
1.23u
Allan Lem
Allan Lem
Last 30d: 129-106-7 (+5.5u)
Under 41.5-110
0.55u
Action IG channel best bet - let’s tail!
Ryan Sura
Ryan Sura
Last 30d: 100-94-0 (+11.5u)
TEN +7.5-110
1u
Chris Gimino
Chris Gimino
Last 30d: 32-37-0 (-1.6u)
E.Demercado u27.5 Rush Yds-135
1u
Grant Neiffer
Grant Neiffer
Last 30d: 36-100-2 (-0.8u)
E.Ayomanor 110+ Receiving Yards Yes+2200
0.05u
E.Ayomanor 60+ Receiving Yards Yes+280
0.1u
E.Ayomanor 70+ Receiving Yards Yes+425
0.1u
E.Ayomanor 80+ Receiving Yards Yes+700
0.1u
E.Ayomanor 90+ Receiving Yards Yes+100
0.1u
E.Ayomanor 100+ Receiving Yards Yes+1440
0.1u
E.Ayomanor o36.5 Rec Yds-112
0.56u
E.Ayomanor 50+ Receiving Yards Yes+170
0.2u
The Degenerates
The Degenerates
Last 30d: 63-65-2 (-6.8u)
E.Ayomanor o32.5 Rec Yds-140
1.4u
Mjaybrod
Mjaybrod
Last 30d: 91-105-3 (-2.7u)
Over 41.5-102
0.98u
Wags Wins
Wags Wins
Last 30d: 208-193-0 (-2.9u)
Over 41-110
1.14u
Greg Matherne
Greg Matherne
Last 30d: 36-43-2 (+6.8u)
TEN +7.5-110
0.5u
Picks Office
Picks Office
Last 30d: 60-78-1 (-14.8u)
Over 41-110
0.91u
Boomer Betz
Boomer Betz
Last 30d: 149-125-2 (+33.2u)
K.Murray u29.5 Rush Yds+100
1u
TEN +8.5-115
0.87u
Matt DiLeo
Matt DiLeo
Last 30d: 46-30-0 (+9.8u)
C.Ward o176.5 Pass Yds-114
0.88u
Markus Markets
Markus Markets
Last 30d: 37-32-0 (+5.9u)
E.Ayomanor o34.5 Rec Yds-110
1u
RocketPlays
RocketPlays
Last 30d: 23-43-0 (+0.4u)
G.Helm 40+ Receiving Yards Yes+850
0.25u
G.Helm o19.5 Rec Yds+200
1u
Babs .
Babs .
Last 30d: 90-94-3 (-3.6u)
M.Carter u11.5 Rush Att-105
1u
Sean Koerner
Sean Koerner
Last 30d: 41-43-0 (-0.6u)
E.Demercado o9.5 Longest Rush-115
0.5u
Last week I nailed the Cardinals post-James Conner RB rotation with Emari’s under 14.5 rush yards. He handled the 3rd down/2 minute work, Trey Benson dominated early downs, and Michael Carter was the main backup on early downs. The only concern was Emari sneaking a bullshit 3rd-and-long draw for a chunk gain.. and there were a couple plays where I thought it might happen. That’s the exact angle I like this week with Trey Benson now out for 4-6 weeks. I expect Michael Carter to take over as the lead early down back with Demercado maintaining the passing down role (while mixing in more than usual on early downs). Demercado has averaged 6.0 yards per carry in his career, mostly because his touches come when defenses aren’t expecting the run. His 8-yard gain last week came in the 2-minute drill, another spot where defenses are rarely keyed on the run. If he mixes in even a little more on early downs, he’ll get extra chances against a Titans defense ranked 31st in run DVOA. I project his median longest run closer to 11.5 yards, with about a 60% to clear 9.5. I’m actually showing slight value on his under 22.5 rush yards too (based on his boom/bust type role) making longest rush the best way to invest in him.
Derek Carty
Derek Carty
Last 30d: 21-25-0 (+0.8u)
M.Carter u2.5 Recs-132
1.32u
THE BLITZ is forecasting 1.58 receptions for Michael Carter compared to 2.56 receptions implied by sportsbooks, so I believe there is some value here. If you take the under, you’d be projected to win 76% of the time, resulting in a 34% ROI. Based on a $100 wager, the expected value here would be $45.41. Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
Gilles Gallant
Gilles Gallant
Last 30d: 23-83-0 (-18.5u)
E.Ayomanor Anytime TD Scorer Yes+450
0.5u
Grant Neiffer
Grant Neiffer
Last 30d: 36-100-2 (-0.8u)
E.Demercado Anytime TD Scorer Yes+255
0.5u
E.Ayomanor Anytime TD Scorer Yes+500
0.25u
Kendra Middleton
Kendra Middleton
Last 30d: 13-8-0 (+3.9u)
TEN +8.5-118
0.85u
Jim Sannes
Jim Sannes
Last 30d: 21-57-0 (-13.7u)
Over 41.5-105
0.95u
Have this total around 45 due to the this game being indoors and both defenses being underwhelming.
Sandy Plashkes
Sandy Plashkes
Last 30d: 95-102-3 (+14.3u)
TEN +10-115
1u
I’m sorry, this line is absurd. I can’t stop betting the Titans but I am so out on the Cardinals. Keep it within 10 Cam.
FTN Fantasy
FTN Fantasy
Last 30d: 60-54-1 (+3.8u)
TEN +8.5-110
0.91u

Titans vs. Cardinals Previews & Analysis

  • Titans vs. Cardinals: Do Hapless Titans Stand a Chance? article feature image

    Titans vs. Cardinals: Do Hapless Titans Stand a Chance?

    Nick Martin
    Oct 5, 2025 UTC
  • Gallant's Anytime TD Picks for Every NFL Game article feature image

    Gallant's Anytime TD Picks for Every NFL Game

    Gilles Gallant
    Oct 5, 2025 UTC
  • Koerner's Week 5 Pick'em & Confidence Rankings article feature image

    Koerner's Week 5 Pick'em & Confidence Rankings

    Sean Koerner
    Oct 5, 2025 UTC
  • NFL Best Bets: Spreads, Totals, ML Picks for Sunday article feature image

    NFL Best Bets: Spreads, Totals, ML Picks for Sunday

    Action Network Staff
    Oct 5, 2025 UTC
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Titans vs. Cardinals Props

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Titans vs. Cardinals Public Betting Percentages

Away Logo

Titans

Public

28%

Bets%

72%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cardinals
3-30-33-01-22-1
Titans
2-40-22-2N/A2-4

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cardinals
3-32-11-22-11-2
Titans
3-32-01-3N/A3-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cardinals
2-4N/AN/A2-10-3
Titans
1-5N/AN/AN/A1-5

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 26thSEAL 20-23+1.5 LU 43.5SEA +102
Sep 21st@SFL 15-16+1.5 WU 44.5SF +105
Sep 14thCARW 27-22-7 LO 45.5ARI -310
Sep 7th@NOW 20-13-5.5 WU 44.5ARI -260
Aug 24thLVW 20-10+3 WU 38.5ARI +140

Titans vs. Cardinals Injury Updates

Titans Injuries

  • Kevin Winston
    S

    Winston is doubtful with hamstring

    Doubtful

  • Kalel Mullings
    RB

    Mullings is out with ankle

    Out

Cardinals Injuries

  • James Conner
    RB

    Conner is out with foot

    Out

  • Kyler Murray
    QB

    Murray is out with foot

    Out

  • Owen Pappoe
    LB

    Pappoe is questionable with quad

    Questionable

  • Trey Benson
    RB

    Benson is out with knee

    Out

  • Tip Reiman
    TE

    Reiman is out with ankle

    Out

Team Stats
327
Total Yards
361
65
Total Plays
64
5
Yards Per Play
5.6
265
YDS
220
21/39
Comps/Atts
23/32
6.073
YPA
5.486
0/1
TDs/INTs
0/0
2/16
Sacks/Yards
3/28
78
Rush Yards
169
24
Attempts
29
3.25
YPC
5.828
1
TDs
3
1
Fumbles Lost
3
1
Interceptions
0

Efficiency

1/2 50%
Redzone
3/4 75%
5/15 0%
3rd Down
7/16 0%
0/1 0%
4th Down
0/0 0%

First Downs

19
Total
16
12
Pass
8
6
Rush
7
1
Penalty
1
6/35
Penalties/Yards
8/47
27:20
Possession
32:40

Titans vs. Cardinals Odds Comparison

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Titans at Cardinals Team Totals

MatchupOverUnder
Titans
1-5
o16.5-107
u16.5-116
Cardinals
2-4
o25-111
u25-111