Cardinals vs. Saints Odds & Betting Predictions - September 7, 2025

Cardinals at Saints

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Arizona Cardinals

1-1

New Orleans Saints

0-1-1

MatchupOpenSpreadTotalMoneyline
Cardinals 1-1	-5.5	-6-110	o42.5-110	-250
Saints 0-1-1	u42.5	+6-110	u42.5-108	+205

Sunday 5:00 p.m.

September 07, 2025

Caesars SuperdomeNew Orleans

NO +6-110

NFL Schedule Release Betting Primer: Notes, Stats and Trends for 2025 Season
Evan Abrams•
May 15, 2025 UTC

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NFL Public Betting

Saints are 3-2 in their last 5 games.
Saints are 4-1 in their last 5 games against the spread
Saints are 3-5 in their road games against the spread
The totals have gone OVER in 3 of Saints' last 5 games
The totals have gone OVER in 4 of Saints' 9 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Saints	7-10	4-5	3-5	1-3	6-7
Cardinals	11-6	6-3	5-3	3-4	7-2

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Saints	8-9	4-5	4-4	2-2	6-7
Cardinals	8-8-1	5-4	3-4-1	5-2	2-6-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Saints	5-12	N/A	N/A	2-2	3-10
Cardinals	8-9	N/A	N/A	3-4	4-5

date	opponent	score	spread	over/under	moneyline
Aug 17th	JAC	W 17-17	+2.5 W	U 40.5	JAC +112
Aug 10th	@LAC	L 13-27	+2.5 L	O 39	LAC +120
Jan 5th	@TB	L 19-27	+14.5 W	O 44.5	TB +722
Dec 29th	LV	L 10-25	+2 L	U 37.5	LV +105
Dec 24th	@GB	L 0-34	+14.5 L	U 43.5	GB +683

passing yards
-
2145
pyds
passing touchdowns
-
15
ptd
rushing yards
Alvin Kamara
950
ryds
rushing touchdowns
Taysom Hill
6
rtd

	Starter	2ND	3RD	4TH
QB	Spencer Rattler	Tyler Shough	Jake Haener
RB	Alvin Kamara	Kendre Miller	Cam Akers	Devin Neal	Velus Jones	Clyde Edwards-Helaire	Marcus Yarns
WR	Rashid Shaheed	Dante Pettis	Moochie Dixon	Roderick Daniels
TE	Juwan Johnson	Moliki Matavao	Treyton Welch	Jack Stoll	Michael Jacobson	Seth Green
LT	Kelvin Banks	Landon Young	Barry Wesley
LG	Trevor Penning	Dillon Radunz	Torricelli Simpkins
C	Erik McCoy	Shane Lemieux	Mike Panasiuk
RG	Cesar Ruiz	Kyle Hergel	Easton Kilty
RT	Taliese Fuaga	Josiah Ezirim	Jonathan Mendoza
RDE	Nathan Shepherd	Jonathan Bullard	Jonah Williams
WLB	Pete Werner	Nephi Sewell	Jaylan Ford	Isaiah Stalbird
MLB	Demario Davis	Danny Stutsman	D'Marco Jackson	Tyreem Powell
LCB	Isaac Yiadom	Quincy Riley	Dalys Beanum
SS	Justin Reid	Jordan Howden	Terrell Burgess
FS	Julian Blackmon	Jonas Sanker	J.T. Gray	Elliott Davison
RCB	Kool-Aid McKinstry	Rico Payton	Rejzohn Wright
P	James Burnip	Kai Kroeger
H	James Burnip	Kai Kroeger
PR	Rashid Shaheed	Dante Pettis	Cedrick Wilson
KR	Rashid Shaheed	Dante Pettis	Kendre Miller
LS	Zach Wood
ROLB	Carl Granderson	Chris Rumph	Fadil Diggs	Jeremiah Martin
K	Blake Grupe	Charlie Smyth
RWR	Brandin Cooks	Mason Tipton	Donovan Peoples-Jones
DT	Bryan Bresee	Vernon Broughton	Jayden Peevy
LWR	Chris Olave	Cedrick Wilson	Kevin Austin
LOLB	Chase Young	Cameron Jordan	Isaiah Foskey	Jasheen Davis
NB	Alontae Taylor	Ugo Amadi	Jayden Price
NT	Davon Godchaux	John Ridgeway	Omari Thomas	Khristian Boyd

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MatchupOverUnder
Cardinals 1-1	N/A	N/A
Saints 0-1-1	N/A	N/A

Cardinals vs. Saints Odds & Betting Predictions - September 7, 2025

Cardinals at Saints

Arizona Cardinals

New Orleans Saints

Cardinals at Saints Odds

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Cardinals vs. Saints Previews & Analysis

NFL Schedule Release Betting Primer: Notes, Stats and Trends for 2025 Season

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Cardinals vs. Saints Public Betting Percentages

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Matchup History

Against the Spread (ATS) History

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Straight-Up (ML) History

Last 5 Matchups

Cardinals vs. Saints Odds Comparison

Cardinals at Saints Team Totals