Cardinals vs. Saints Odds & Betting Predictions - September 7, 2025
Cardinals at Saints
5:00 pm • CBSCardinals at Saints Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Cardinals 8-9 | -4 | -4.5-110 | o41.5-118 | -200 |
 Saints 5-12 | u42.5 | +4.5-110 | u41.5-105 | +165 |
Cardinals vs. Saints Previews & Analysis
Cardinals vs. Saints Props
Prop Projections
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Prop Odds Comparison
Line Movement Tracker
Cardinals vs. Saints Public Betting Percentages
Betting Trends
- Saints are 3-2 in their last 5 games.
- Saints are 4-1 in their last 5 games against the spread
- Saints are 3-5 in their road games against the spread
- The totals have gone OVER in 3 of Saints' last 5 games
- The totals have gone OVER in 4 of Saints' 9 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Saints vs. Cardinals Injury Updates
Saints Injuries
- Alvin KamaraRB
Kamara is doubtful with groin
Doubtful
- Taysom HillTE
Hill is out with knee
Out
- Nathan ShepherdDT
Shepherd is questionable with eye
Questionable
- Isaac YiadomCB
Yiadom is questionable with pelvis
Questionable
- J.T. GrayDB
Gray is questionable with back
Questionable
- Erik McCoyC
McCoy is out with elbow
Out
- Pete WernerLB
Werner is out with concussion
Out
- Chris OlaveWR
Olave is out with concussion
Out
- D'Marco JacksonLB
Jackson is out with ankle
Out
- John RidgewayDT
Ridgeway is questionable with oblique
Questionable
- Nephi SewellLB
Sewell is questionable with knee
Questionable
- Rashid ShaheedWR
Shaheed is out with knee
Out
- Kendre MillerRB
Miller is doubtful with concussion
Doubtful
- Nick SaldiveriOL
Saldiveri is out with knee
Out
- Bub MeansWR
Means is out with ankle
Out
- Rico PaytonCB
Payton is questionable with back
Questionable
Cardinals Injuries
- Calais CampbellDE
Campbell is questionable with rest
Questionable
- Dalvin TomlinsonDT
Tomlinson is questionable with knee
Questionable
- James ConnerRB
Conner is out with knee
Out
- Evan BrownOL
Brown is questionable with neck
Questionable
- Sean Murphy-BuntingCB
Murphy-Bunting is questionable with hand
Questionable
- Jalen ThompsonS
Thompson is questionable with ankle
Questionable
- Jonah WilliamsOL
Williams is questionable with illness
Questionable
- Mack WilsonLB
Wilson is questionable with ankle
Questionable
- Mykal WalkerOLB
Walker is questionable with illness
Questionable
- Blake GillikinP
Gillikin is out with foot
Out
- Baron BrowningOLB
Browning is questionable with neck
Questionable
- Simi FehokoWR
Fehoko is questionable with elbow
Questionable
- Joey BlountS
Blount is out with ribs
Out
- Paris JohnsonOL
Johnson is out with knee
Out
- Michael WilsonWR
Wilson is questionable with hamstring
Questionable
- Jammie RobinsonS
Robinson is doubtful with knee
Doubtful
- Dante StillsDE
Stills is questionable with back
Questionable
- Emari DemercadoRB
Demercado is out with back
Out
- Trey BensonRB
Benson is out with ankle
Out
- Elijah JonesDB
Jones is out with ankle
Out
- Xavier ThomasDE
Thomas is questionable with back
Questionable
- passing yards
-2145pyds - passing touchdowns-15ptd
- rushing yards
Alvin Kamara950ryds - rushing touchdowns
Taysom Hill6rtd
| Starter | 2ND | 3RD | 4TH | |
|---|---|---|---|---|
| QB | Derek Carr | Jake Haener | Spencer Rattler | |
| RB | Alvin Kamara | Jamaal Williams | Kendre Miller | Jordan Mims |
| WR | Rashid Shaheed | Bub Means | Mason Tipton | |
| TE | Juwan Johnson | Foster Moreau | Taysom Hill | Michael Jacobson |
| LT | Taliese Fuaga | Landon Young | ||
| LG | Lucas Patrick | Nick Saldiveri | ||
| C | Erik McCoy | Shane Lemieux | ||
| RG | Cesar Ruiz | Kyle Hergel | ||
| RT | Trevor Penning | Olisaemeka Udoh | Josiah Ezirim | |
| LDE | Cameron Jordan | Payton Turner | Trajan Jeffcoat | |
| LDT | Khalen Saunders | Khristian Boyd | ||
| RDT | Nathan Shepherd | Bryan Bresee | ||
| RDE | Carl Granderson | Chase Young | Isaiah Foskey | |
| WLB | Pete Werner | Isaiah Stalbird | ||
| MLB | Demario Davis | D'Marco Jackson | ||
| SLB | Willie Gay | Jaylan Ford | Anfernee Orji | |
| LCB | Paulson Adebo | Shemar Jean-Charles | Rejzohn Wright | |
| SS | Jordan Howden | J.T. Gray | Millard Bradford | |
| FS | Tyrann Mathieu | Will Harris | ||
| RCB | Kool-Aid McKinstry | Rico Payton | ||
| P | Matthew Hayball | |||
| H | Matthew Hayball | |||
| PR | Rashid Shaheed | Mason Tipton | ||
| KR | Rashid Shaheed | Jamaal Williams | ||
| LS | Zach Wood | |||
| K | Blake Grupe | Charlie Smyth | ||
| RWR | Chris Olave | Cedrick Wilson | ||
| NB | Alontae Taylor | Ugo Amadi | ||
| FB | Adam Prentice | |||
| LWR | Kevin Austin |
Cardinals vs. Saints Odds Comparison
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Cardinals at Saints Team Totals
MatchupOverUnder | ||
|---|---|---|
Cardinals 8-9 | N/A | N/A |
Saints 5-12 | N/A | N/A |