Packers vs. Browns Odds & Betting Predictions - September 21, 2025

Packers at Browns

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Packers at Browns Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Packers
2-0
-6.5
-8.5-111
o41.5-110
-425
Browns
0-2
u43.5
+8.5-109
u41.5-110
+337
location pinSunday 5:00 p.m.
September 21, 2025
Huntington Bank FieldCleveland
thermometer image78°Fahrenheit
rain image0%Rain
wind image9Wind
Packers vs. Browns Expert Picks
Anders
Anders
Last 30d: 13-12-0 (-0.7u)
CLE +390
0.25u
CLE +8.5-110
1.1u
Outright. Reeks of the Browns/Niners game from 2 years ago. Browns honestly 2 decent datapoints despite being 0-2 and losing bad last week scoreboard wise. Think anything above 7 at home is too many
Boomer Betz
Boomer Betz
Last 30d: 124-135-0 (-2.3u)
CLE +9.5-129
1u
@braydenhenry
FTN Fantasy
FTN Fantasy
Last 30d: 62-94-0 (-37.5u)
CLE +9-110
1u
Moneyline Hacks
Moneyline Hacks
Last 30d: 101-122-5 (+39.7u)
Under 42.5-110
1.8u
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Packers vs. Browns Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Packers vs. Browns Public Betting Percentages

Away Logo

Packers

Public

37%

Bets%

63%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Browns
1-11-00-1N/A1-1
Packers
2-02-0N/A2-0N/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Browns
1-10-11-0N/A1-1
Packers
0-20-2N/A0-2N/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Browns
0-2N/AN/AN/A0-2
Packers
2-0N/AN/A2-0N/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 14th@BALL 17-41+12.5 LO 46.5BAL +640
Sep 7thCINL 16-17+4.5 WU 47.5CIN +185
Aug 23rdLAW 19-17-10 LU 37CLE -550
Aug 16th@PHIW 22-13+2.5 WU 36.5CLE +120
Aug 8th@CARW 30-10+5.5 WO 33.5CLE +210

Browns vs. Packers Injury Updates

Browns Injuries

  • Mike Hall
    DT

    Hall is out with knee

    Out

Packers Injuries

  • Zayne Anderson
    S

    Anderson is questionable with knee

    Questionable

  • Christian Watson
    WR

    Watson is out with knee

    Out

  • Jayden Reed
    WR

    Reed is out with collarbone

    Out

  • MarShawn Lloyd
    RB

    Lloyd is out with hamstring

    Out

  • Barryn Sorrell
    DE

    Sorrell is questionable with knee

    Questionable

Player Stats
  • passing yards
    Joe Flacco logo
    Joe Flacco
    489
    pyds
  • passing touchdowns
    Joe Flacco logo
    Joe Flacco
    2
    ptd
  • rushing yards
    Quinshon Judkins logo
    Quinshon Judkins
    61
    ryds
  • rushing touchdowns
    Raheim Sanders logo
    Raheim Sanders
    1
    rtd
Depth Charts
Right Arrow
Starter2ND3RD4TH
QBJoe FlaccoDillon GabrielShedeur SandersDeshaun Watson
RBJerome FordQuinshon JudkinsDylan SampsonAhmani Marshall
WRJamari ThrashDeAndre CarterGage LarvadainCade McDonald
TEDavid NjokuHarold FanninBlake WhiteheartBrenden BatesSal Cannella
LTDawand JonesCornelius Lucas
LGJoel BitonioTeven Jenkins
CEthan PocicLuke Wypler
RGWyatt TellerZak Zinter
RTJack Conklin
LDEAlex WrightIsaiah McGuireJulian OkwaraK.J. Henry
RDEMyles GarrettJoe Tryon-ShoyinkaCameron Thomas
WLBDevin BushJerome BakerWinston Reid
MLBCarson SchwesingerMohamoud DiabateEaston Mascarenas-Arnold
LCBDenzel WardDom Jones
SSGrant DelpitRayshawn JenkinsDonovan McMillon
FSRonnie HickmanDamontae KazeeChristopher Edmonds
RCBGreg Newsome
PCorey Bojorquez
HCorey Bojorquez
PRDeAndre CarterGage LarvadainKaden Davis
KRDeAndre CarterKaden Davis
LSRex Sunahara
RWRJerry JeudyIsaiah BondKaden Davis
NBCameron MitchellMyles HardenLaMareon James
DTMason GrahamMike HallSam KamaraRalph Holley
LWRCedric TillmanDavid Bell
NTMaliek CollinsShelby HarrisAdin Huntington
KAndre Szmyt
Team Stats
457
YDS
485
35/53
Comps/Atts
59/93
9.057
YPA
5.462
4/0
TDs/INTs
3/3
2/23
Sacks/Yards
4/23
213
Rush Yards
164
55
Attempts
46
3.873
YPC
3.565
2
TDs
1

Turnovers

Fumbles Lost
0
Interceptions
3

Efficiency

6/9 66.67%
Redzone
4/5 80%
9/22 0%
3rd Down
16/34 0%
1/2 0%
4th Down
3/6 0%

First Downs

36
Total
39
22
Pass
23
10
Rush
12
4
Penalty
4
/
Penalties/Yards
/
Possession

Packers vs. Browns Odds Comparison

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Packers at Browns Team Totals

MatchupOverUnder
Packers
2-0
N/A
N/A
Browns
0-2
N/A
N/A