Cowboys vs. Panthers Odds & Betting Predictions - October 12, 2025
Cowboys at Panthers
5:00 pm • FOXCowboys at Panthers Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Cowboys 2-2-1 | -1.5 | -3.5-105 | o49.5-110 | -185 |
 Panthers 2-3 | u46.5 | +3.5-115 | u49.5-110 | +154 |
Bank of America StadiumCharlotte
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Cowboys vs. Panthers Expert Picks
Kendra Middleton
Last 30d: 10-7-0 (+2.1u)
DAL -3.5+110
1u
Brandon Kravitz
Last 30d: 46-63-0 (-9.0u)
CAR +170
0.4u
CAR +3+100
1u
Plant the Flag! ⛳️ @TheFavoritesPodcast
my power ratings make this Cowboys -1. So I like that first and foremost. But as I’ve mentioned, my numbers are far from gospel. Its more of a guide to get me pointed in the right direction. The Cowboys are playing their 3rd road game in their past 4 games, big divisional matchup with Washington on deck…Carolina is parked at home, we’ve got a Rico Dowdle revenge game (kidding, sort of)…the Cowboys have the worst graded run D in the NFL – taking on a guy that just rumbled for 200 yards and used to play for the team. Its at least enough to get me to the window. Do keep in mind, CeeDee Lamb might be back – that would push this line to 4/4.5 – I’ll take the even money at +3 and avoid the juice of the 3.5.
Cowboys vs. Panthers Previews & Analysis
Cowboys vs. Panthers Props
Prop Projections
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Prop Odds Comparison
Line Movement Tracker
Cowboys vs. Panthers Public Betting Percentages
Betting Trends
- Panthers are 2-3 in their last 5 games.
- Panthers are 3-2 in their last 5 games against the spread
- Panthers are 1-2 in their road games against the spread
- The totals have gone OVER in 3 of Panthers' last 5 games
- The totals have gone OVER in 1 of Panthers' 2 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Cowboys vs. Panthers Injury Updates
Cowboys Injuries
- Miles SandersRB
Sanders is out with ankle
Out
- CeeDee LambWR
Lamb is out with ankle
Out
- Perrion WinfreyDT
Winfrey is out with back
Out
- KaVontae TurpinWR
Turpin is out with foot
Out
- Jonathan MingoWR
Mingo is questionable with knee
Questionable
Panthers Injuries
- David MooreWR
Moore is out with elbow
Out
- Chuba HubbardRB
Hubbard is questionable with calf
Questionable
- Ikem EkwonuT
Ekwonu is doubtful with illness
Doubtful
- Damarri MathisCB
Mathis is out with knee
Out
- Ja'Tavion SandersTE
Sanders is out with ankle
Out
- Jalen CokerWR
Coker is out with quad
Out
Player Stats
- passing yards
Bryce Young951pyds - passing touchdownsBryce Young7ptd
- rushing yards
Rico Dowdle289ryds - rushing touchdownsRico Dowdle2rtd
Depth Charts
| Starter | 2ND | 3RD | 4TH | |
|---|---|---|---|---|
| QB | Bryce Young | Andy Dalton | ||
| RB | Chuba Hubbard | Rico Dowdle | Trevor Etienne | |
| WR | Jimmy Horn | Hunter Renfrow | ||
| TE | Ja'Tavion Sanders | Mitchell Evans | James Mitchell | Bryce Pierre |
| LT | Ikem Ekwonu | Brady Christensen | Michael Tarquin | |
| LG | Damien Lewis | |||
| C | Austin Corbett | Cade Mays | ||
| RG | Robert Hunt | Chandler Zavala | ||
| RT | Taylor Moton | Yosh Nijman | Brandon Walton | |
| LDE | Derrick Brown | LaBryan Ray | Jaden Crumedy | |
| RDE | Tershawn Wharton | A'Shawn Robinson | Jared Harrison-Hunte | |
| LCB | Mike Jackson | |||
| SS | Tre'von Moehrig | Lathan Ransom | ||
| FS | Nick Scott | Demani Richardson | ||
| RCB | Jaycee Horn | Corey Thornton | Akayleb Evans | |
| P | Sam Martin | |||
| H | Sam Martin | |||
| PR | Trevor Etienne | Jimmy Horn | David Moore | |
| KR | Jimmy Horn | Trevor Etienne | David Moore | |
| LS | JJ Jansen | |||
| NT | Bobby Brown | Cam Jackson | ||
| RILB | Christian Rozeboom | Mapalo Mwansa | ||
| RWR | Xavier Legette | Jalen Coker | Ja'seem Reed | |
| NB | Chau Smith-Wade | Michael Reid | Trevian Thomas | |
| LILB | Trevin Wallace | Claudin Cherelus | Krys Barnes | Bam Martin-Scott |
| LWR | Tetairoa McMillan | David Moore | Brycen Tremayne | |
| ROLB | D.J. Wonnum | Nic Scourton | ||
| LOLB | Patrick Jones | Princely Umanmielen | Thomas Incoom | Boogie Basham |
| K | Ryan Fitzgerald |
Team Stats
1361
YDS
935
142/200
Comps/Atts
111/180
6.985
YPA
5.606
10/4
TDs/INTs
8/4
7/36
Sacks/Yards
9/74
13/19 68.42%
Redzone
10/15 66.67%
26/60 0%
3rd Down
26/66 0%
4/6 0%
4th Down
8/13 0%
Cowboys vs. Panthers Odds Comparison
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Cowboys at Panthers Team Totals
MatchupOverUnder | ||
|---|---|---|
Cowboys 2-2-1 | N/A | N/A |
Panthers 2-3 | N/A | N/A |