Panthers vs. Patriots Odds & Betting Predictions - September 28, 2025

Panthers at Patriots

5:00 pm • FOX
13 - 42

Panthers at Patriots Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Panthers
3-3
+3.5
+5.5-110
o42.5-110
+200
Patriots
4-2
u45.5
-5.5-110
u42.5-110
-250
location pinSunday 5:00 p.m.
September 28, 2025
Gillette StadiumFoxborough
Panthers vs. Patriots Expert Picks
Stuck 🚨
Stuck 🚨
Last 30d: 67-65-2 (+2.6u)
CAR +10.5 (Live)-106
0.1u
Went for small middle here. Pats fortunate so far and Panthers backdoor kings
Mjaybrod
Mjaybrod
Last 30d: 91-105-3 (-2.7u)
NE -3.5 (Live)-105
0.48u
Rosa gang
The Degenerates
The Degenerates
Last 30d: 63-65-2 (-6.8u)
CAR +5.5 (Live)-110
1.1u
Chris Raybon
Chris Raybon
Last 30d: 28-35-1 (+9.4u)
D.Moore Anytime TD Scorer Yes+850
0.5u
Wags Wins
Wags Wins
Last 30d: 208-193-0 (-2.9u)
NE -4.5-115
1.3u
Chris Gimino
Chris Gimino
Last 30d: 32-37-0 (-1.6u)
C.Hubbard u14.5 Rush Att-117
0.85u
Brian Bitler
Brian Bitler
Last 30d: 71-64-1 (+12.3u)
NE -5.5-108
2.78u
Vegas Refund
Vegas Refund
Last 30d: 45-38-2 (+3.6u)
NE -5.5-105
1u
Player Props
Player Props
Last 30d: 15-14-0 (+0.1u)
H.Henry o37.5 Rec Yds-118
0.85u
R.Stevenson o31.5 Rush Yds-114
0.88u
The Propfessor
The Propfessor
Last 30d: 37-44-0 (+9.2u)
T.Henderson o37.5 Rush Yds-118
1u
Boomer Betz
Boomer Betz
Last 30d: 149-125-2 (+33.2u)
T.McMillan Anytime TD Scorer Yes+205
1u
@braydenhenry
Cam Is Money
Cam Is Money
Last 30d: 59-90-3 (-28.7u)
T.Henderson o57.5 Rush + Rec Yds-115
1u
Sean Koerner
Sean Koerner
Last 30d: 41-43-0 (-0.6u)
T.McMillan o62.5 Rec Yds-114
0.57u
Nice buy-low on Tet after his career-worst 3/48/0 in a 30–0 game where Carolina barely needed to throw. As 5.5-point road dogs, they should be pushed into a more pass-heavy script. The Bryce–Tet chemistry keeps ticking up each week, and I expect that to continue as the season goes. Christian Gonzalez should be back and could shadow. The two go way back to Arizona vs. Oregon. I actually waited for Gonzalez to be ruled in and the number dipped to 62.5, which I wanted. New England plays man at a high rate (7th most, likely higher with Gonzalez active) and Tet has crushed man, leading all qualified WRs at 5.88 YPRR vs man. Gonzalez may break up a couple, but Bryce has been more willing to give Tet chances, and they have just missed on a few big ones. He is also excellent after the catch for an X receiver. I have this closer to 69.5 yards with about 58% to clear 62.5. Worth a small ladder sprinkle: 100+ yards at +351 (DK); I price that closer to +300.
T.McMillan 100+ Receiving Yards Yes+351
0.1u
Proj closer to +300
Babs .
Babs .
Last 30d: 90-94-3 (-3.6u)
H.Henry o3.5 Recs-115
1u
Derek Carty
Derek Carty
Last 30d: 21-25-0 (+0.8u)
R.Stevenson u1.5 Recs+155
1.55u
There is a value opportunity on Rhamondre Stevenson's receptions prop. THE BLITZ is projecting him to record 1.65 receptions, while sportsbooks implies 2.34. The model believes there is a 55% chance he records fewer than 1.5 receptions, so there is some value on the under at +155. Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
Nick Giffen
Nick Giffen
Last 30d: 60-108-1 (+22.6u)
T.Henderson o14.5 Rec Yds-125
1.25u
TreVeyon Henderson over 14.5 rec yds (-125 at BetMGM, -120 at Hard Rock) Could be in line for an increase in snaps after both Rhamondre Stevenson and Antonio Gibson had fumbles last week Henderson has the highest targets per route run (TPRR) on the Patriots when Drake Maye has a clean pocket, and faces a CAR defense that's by far last in pressure rate this year Henderson also has the second-highest TPRR on the Patriots against Cover 3, of which CAR plays 2nd most in the NFL In 2 games against other Cover 3-heavy teams (Wk 1 vs LV and Wk 3 vs PIT), Henderson has 9 catches on 9 targets for 43 yards, an average of 4.5 and 21.5 yds per game Yes, NE is more likely to be in a run-heavy script here, but even accounting for that, the low pressure and high Cover 3 should help his target share on those pass attempts CAR last year allowed 8.2 yards per catch to RBs, and this year 6.9, which is bottom half, so he should get there on 3 catches, and could even get there on 2.5 Projecting a median closer to 19.5 rec yds ... each yard is worth around 2.75%, so over 14.5 -120 at HR or -125 at MGM is better than over 15.5 -116 at DK or over 16.5 -114 at FD, but all three are still value by my numbers.
Will Brinson
Will Brinson
Last 30d: 33-23-1 (+8.2u)
NE -5.5-110
1u
Roger Goodell
Roger Goodell
Last 30d: 47-32-3 (+8.4u)
H.Henry o38.5 Rec Yds-115
0.43u
R.Stevenson o31.5 Rush Yds-114
0.66u
Gilles Gallant
Gilles Gallant
Last 30d: 23-83-0 (-18.5u)
D.Moore Anytime TD Scorer Yes+850
0.2u
Played 97% of snaps with Legette out in W3 and he out again in W4. Panthers also missing Hubbard and Sanders so Moore should see “more” targets this week. And if CB Christian Gonzalez plays, he’ll likely shadow Tet McMillan.
The Favorites Podcast
The Favorites Podcast
Last 30d: 13-17-0 (-3.5u)
NE -5.5-108
1u
FTN Fantasy
FTN Fantasy
Last 30d: 60-54-1 (+3.8u)
NE -1.5 (1Q)+108
1u
NE -2.5 (1H)-125
0.8u
NE -5.5-105
0.95u
Gilles Gallant
Gilles Gallant
Last 30d: 23-83-0 (-18.5u)
B.Young o0.5 Int-115
0.58u
NFL INT Picks - W4
Boomer Betz
Boomer Betz
Last 30d: 149-125-2 (+33.2u)
D.Maye u218.5 Pass Yds-115
0.87u
Kyle Murray
Kyle Murray
Last 30d: 62-56-2 (+11.4u)
T.McMillan o67.5 Rec Yds-115
1.15u
C.Hubbard u51.5 Rush Yds-115
1u
T.Henderson o11.5 Longest Rush+102
1u
Action Pod NFL Picks
Action Pod NFL Picks
Last 30d: 57-131-0 (-19.7u)
NE -5.5-108
0.93u
@sundaysixpack @Stuckey2 2 https://myaction.app/JNv2zeOUXWb
Sunday Six Pack
Sunday Six Pack
Last 30d: 16-14-0 (+0.3u)
NE -5.5-108
1u
Kenny Ducey
Kenny Ducey
Last 30d: 34-24-1 (+7.7u)
NE -5.5-110
1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 102-144-4 (+18.3u)
T.Henderson Anytime TD Scorer Yes+180
0.18u
Mjaybrod
Mjaybrod
Last 30d: 91-105-3 (-2.7u)
NE o23.5 Team Total-120
0.83u
Drake Maye but wearing a durag and smoking a blunt
Brandon Kravitz
Brandon Kravitz
Last 30d: 59-79-1 (-12.2u)
CAR +213
0.5u
I have the Panthers rated higher than the Pats, I feel a moral obligation to bet them at 2-1 odds.
Jim Sannes
Jim Sannes
Last 30d: 21-57-0 (-13.7u)
CAR +5.5-110
1u
Have the Patriots favored by less than a field goal. Panthers have been more fine than abysmal, so 5.5 is a big number.
Stuck 🚨
Stuck 🚨
Last 30d: 67-65-2 (+2.6u)
NE -5.5-110
0.55u
Matt Moore
Matt Moore
Last 30d: 15-14-0 (-0.2u)
NE -5.5-110
1u
FTN Fantasy
FTN Fantasy
Last 30d: 60-54-1 (+3.8u)
NE -4.5-105
0.95u
Moneyline Hacks
Moneyline Hacks
Last 30d: 122-119-4 (+38.0u)
CAR +4.5-110
1u
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Panthers vs. Patriots Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Panthers vs. Patriots Public Betting Percentages

Away Logo

Panthers

Public

76%

Bets%

24%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Patriots
4-21-23-02-12-1
Panthers
4-23-01-2N/A4-2

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Patriots
2-41-21-21-21-2
Panthers
4-22-12-1N/A4-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Patriots
4-2N/AN/A2-12-1
Panthers
3-3N/AN/AN/A3-3

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 21stPITL 14-21+1.5 LU 44.5PIT -104
Sep 14th@MIAW 33-27+2.5 WO 43.5NE +110
Sep 7thLVL 13-20-2.5 LU 44.5LV -148
Aug 22nd@NYGL 10-42+4.5 LO 36.5NYG +185
Aug 16th@MINW 20-12+1.5 WU 37NE +105

Patriots vs. Panthers Injury Updates

Patriots Injuries

  • Antonio Gibson
    RB

    Gibson is out with knee

    Out

  • Charles Woods
    CB

    Woods is questionable with concussion

    Questionable

Panthers Injuries

  • David Moore
    WR

    Moore is out with elbow

    Out

  • Chuba Hubbard
    RB

    Hubbard is out with calf

    Out

  • Damarri Mathis
    CB

    Mathis is out with knee

    Out

  • Ja'Tavion Sanders
    TE

    Sanders is out with ankle

    Out

  • Jalen Coker
    WR

    Coker is out with quad

    Out

Team Stats
326
Total Yards
307
65
Total Plays
48
5
Yards Per Play
6.4
208
YDS
203
23/36
Comps/Atts
14/18
5.324
YPA
10.684
2/0
TDs/INTs
2/0
1/11
Sacks/Yards
1/0
129
Rush Yards
104
28
Attempts
29
4.607
YPC
3.586
0
TDs
3
0
Fumbles Lost
0
0
Interceptions
0
2/2 100%
Redzone
4/4 100%
5/14 0%
3rd Down
3/9 0%
1/3 0%
4th Down
1/1 0%

First Downs

21
Total
16
11
Pass
8
8
Rush
7
2
Penalty
1
5/29
Penalties/Yards
7/54
35:14
Possession
24:46

Panthers vs. Patriots Odds Comparison

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Panthers at Patriots Team Totals

MatchupOverUnder
Panthers
3-3
o18-111
u18-116
Patriots
4-2
o24-109
u24-117