Titans vs. Colts Odds & Betting Predictions - October 26, 2025

Titans at Colts

8:25 pm • CBS
14 - 38

Titans at Colts Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Titans
1-8
+12
+14.5-106
o48-110
+900
Colts
7-2
u44.5
-14.5-114
u48-110
-1600
location pinSunday 8:25 p.m.
October 26, 2025
Lucas Oil StadiumIndianapolis
Titans vs. Colts Expert Picks
FTN Fantasy
FTN Fantasy
Last 30d: 51-49-0 (+4.0u)
TEN +16.5 (Live)-105
1u
TEN +19.5 (Live)-110
1u
Chris Raybon
Chris Raybon
Last 30d: 20-32-1 (-10.8u)
C.Dike Anytime TD Scorer Yes+480
1u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 210-189-2 (-1.7u)
TEN u14.5 Team Total+116
1.86u
Matt DiLeo
Matt DiLeo
Last 30d: 43-44-0 (-7.4u)
C.Ward o207.5 Pass Yds-112
0.45u
D.Jones u30.5 Pass Att-130
0.38u
Derek Carty
Derek Carty
Last 30d: 25-22-0 (+7.5u)
A.Abdullah u3.5 Rush Att-115
1u
There may be some value on the rush attempts prop for Ameer Abdullah. THE BLITZ is projecting him to record 0.80 rush attempts, and the oddsmakers are implying 3.79. The model believes there is a 86% chance he records fewer than 3.5 rush attempts. If you can get the under at -116 or better, there is some great value here. (This play is good down to at least -299.) Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
Brian Bitler
Brian Bitler
Last 30d: 82-83-2 (-12.5u)
TEN +14.5-102
3u
RocketPlays
RocketPlays
Last 30d: 38-76-0 (+3.0u)
A.Pierce o19.5 Longest Reception-115
0.87u
Gilles Gallant
Gilles Gallant
Last 30d: 31-91-1 (-10.7u)
D.Jones 2+ TDs Yes+2800
0.1u
TD 🪜🪜
Babs .
Babs .
Last 30d: 106-123-3 (-13.6u)
A.Abdullah o0.5 Recs-120
0.83u
Nick Giffen
Nick Giffen
Last 30d: 54-71-0 (+10.6u)
C.Ward o34.5 Pass Att-109
1u
Cam Ward over 34.5 Pass Att (-109 at DK ... there's a single 33.5 -130 at MGM but most of the market is at 34.5 so I'll track it at that) Ward's median is 34 this year, but the Titans are 14.5-point dogs to the Colts here so we can expect more than 34 as a starting point here. The Colts actually have a below average time of possession, especially compared to the opponents TEN has faced this year, so there will likley be more time TEN spends with the ball That's in part thanks to the Colts extreme explosiveness with Jonathan Taylor on the ground and several big plays through the air Colts project as the most explosive team overall in Week 8 The Colts have also made a ton of big defensive plays (6th most turnovers forced per game) to leave them with short fields or even defensive scores, handing the ball back to their opponent quickly I'm projecting closer to 36 pass attempts with upside for around 39
Brandon Anderson
Brandon Anderson
Last 30d: 57-104-0 (+10.4u)
TEN +900
0.25u
It would be tough to find two teams going in more opposite directions, and that explains one of the biggest spreads of the season thus far, with the Colts favored by two touchdowns. Indianapolis has the league's best offense. The Colts rank first in Offensive DVOA, tops both rushing and passing. The Titans offense? It ranks dead last in that metric. Tennessee's defense has been slightly better — can't be worse! — but might be headed in the wrong direction thanks to a couple key injuries. DT Jeffrey Simmons has played like a DPOY contender even on a miserable team. His absence along with CB L'Jarius Sneed leave this defense badly lacking in talent. They weren't very good to start with. The Titans have allowed 27.4 PPG, even with that pair healthy, and that includes a season-high 41 to the Colts in a blowout Week 3 loss. The Colts offense has scored at least 29 points in all but one game this season, with games of 29, 31, 33, 38, 40, and 41 points. That's all we need to know to back Indy's team total over 30.5 points (-109, BetRivers), and we can take a small escalator and go over 34.5 points at +180 (DraftKings) and over 39.5 at +375 (bet365). Okay, ready for the crazy part? If the Colts don't go over the team total, something has gone wrong — and maybe the Titans steal this. It sounds crazy now, but since 2018, moneyline underdogs between +750 and +1000 are 4-14 straight up. That doesn't sound great, but if you just blindly bet the long-shot underdog in those spots, you're sitting on a 106% ROI. Those teams either get blown out or pull a shocker, and these rivals had played eight straight single-digit games before the Week 3 blowout. I think this spread is inflated and would make it closer to -11.5, which would typically mean a moneyline around +450. We're getting twice the payout so let's nibble a Titans ML at +900 (ESPN Bet) and hope we either get a shocking upset or a Colts blowout.
IND o39.5 Team Total+375
0.1u
It would be tough to find two teams going in more opposite directions, and that explains one of the biggest spreads of the season thus far, with the Colts favored by two touchdowns. Indianapolis has the league's best offense. The Colts rank first in Offensive DVOA, tops both rushing and passing. The Titans offense? It ranks dead last in that metric. Tennessee's defense has been slightly better — can't be worse! — but might be headed in the wrong direction thanks to a couple key injuries. DT Jeffrey Simmons has played like a DPOY contender even on a miserable team. His absence along with CB L'Jarius Sneed leave this defense badly lacking in talent. They weren't very good to start with. The Titans have allowed 27.4 PPG, even with that pair healthy, and that includes a season-high 41 to the Colts in a blowout Week 3 loss. The Colts offense has scored at least 29 points in all but one game this season, with games of 29, 31, 33, 38, 40, and 41 points. That's all we need to know to back Indy's team total over 30.5 points (-109, BetRivers), and we can take a small escalator and go over 34.5 points at +180 (DraftKings) and over 39.5 at +375 (bet365). Okay, ready for the crazy part? If the Colts don't go over the team total, something has gone wrong — and maybe the Titans steal this. It sounds crazy now, but since 2018, moneyline underdogs between +750 and +1000 are 4-14 straight up. That doesn't sound great, but if you just blindly bet the long-shot underdog in those spots, you're sitting on a 106% ROI. Those teams either get blown out or pull a shocker, and these rivals had played eight straight single-digit games before the Week 3 blowout. I think this spread is inflated and would make it closer to -11.5, which would typically mean a moneyline around +450. We're getting twice the payout so let's nibble a Titans ML at +900 (ESPN Bet) and hope we either get a shocking upset or a Colts blowout.
IND o34.5 Team Total+180
0.45u
It would be tough to find two teams going in more opposite directions, and that explains one of the biggest spreads of the season thus far, with the Colts favored by two touchdowns. Indianapolis has the league's best offense. The Colts rank first in Offensive DVOA, tops both rushing and passing. The Titans offense? It ranks dead last in that metric. Tennessee's defense has been slightly better — can't be worse! — but might be headed in the wrong direction thanks to a couple key injuries. DT Jeffrey Simmons has played like a DPOY contender even on a miserable team. His absence along with CB L'Jarius Sneed leave this defense badly lacking in talent. They weren't very good to start with. The Titans have allowed 27.4 PPG, even with that pair healthy, and that includes a season-high 41 to the Colts in a blowout Week 3 loss. The Colts offense has scored at least 29 points in all but one game this season, with games of 29, 31, 33, 38, 40, and 41 points. That's all we need to know to back Indy's team total over 30.5 points (-109, BetRivers), and we can take a small escalator and go over 34.5 points at +180 (DraftKings) and over 39.5 at +375 (bet365). Okay, ready for the crazy part? If the Colts don't go over the team total, something has gone wrong — and maybe the Titans steal this. It sounds crazy now, but since 2018, moneyline underdogs between +750 and +1000 are 4-14 straight up. That doesn't sound great, but if you just blindly bet the long-shot underdog in those spots, you're sitting on a 106% ROI. Those teams either get blown out or pull a shocker, and these rivals had played eight straight single-digit games before the Week 3 blowout. I think this spread is inflated and would make it closer to -11.5, which would typically mean a moneyline around +450. We're getting twice the payout so let's nibble a Titans ML at +900 (ESPN Bet) and hope we either get a shocking upset or a Colts blowout.
IND o30.5 Team Total-109
0.92u
It would be tough to find two teams going in more opposite directions, and that explains one of the biggest spreads of the season thus far, with the Colts favored by two touchdowns. Indianapolis has the league's best offense. The Colts rank first in Offensive DVOA, tops both rushing and passing. The Titans offense? It ranks dead last in that metric. Tennessee's defense has been slightly better — can't be worse! — but might be headed in the wrong direction thanks to a couple key injuries. DT Jeffrey Simmons has played like a DPOY contender even on a miserable team. His absence along with CB L'Jarius Sneed leave this defense badly lacking in talent. They weren't very good to start with. The Titans have allowed 27.4 PPG, even with that pair healthy, and that includes a season-high 41 to the Colts in a blowout Week 3 loss. The Colts offense has scored at least 29 points in all but one game this season, with games of 29, 31, 33, 38, 40, and 41 points. That's all we need to know to back Indy's team total over 30.5 points (-109, BetRivers), and we can take a small escalator and go over 34.5 points at +180 (DraftKings) and over 39.5 at +375 (bet365). Okay, ready for the crazy part? If the Colts don't go over the team total, something has gone wrong — and maybe the Titans steal this. It sounds crazy now, but since 2018, moneyline underdogs between +750 and +1000 are 4-14 straight up. That doesn't sound great, but if you just blindly bet the long-shot underdog in those spots, you're sitting on a 106% ROI. Those teams either get blown out or pull a shocker, and these rivals had played eight straight single-digit games before the Week 3 blowout. I think this spread is inflated and would make it closer to -11.5, which would typically mean a moneyline around +450. We're getting twice the payout so let's nibble a Titans ML at +900 (ESPN Bet) and hope we either get a shocking upset or a Colts blowout.
Kyle Murray
Kyle Murray
Last 30d: 66-83-2 (-13.6u)
C.Ward o1.5 Rush Att-115
1u
TAN Pod Touchdown Show
TAN Pod Touchdown Show
Last 30d: 28-90-2 (-1.6u)
C.Dike Anytime TD Scorer Yes+475
0.5u
J.Taylor 3+ TDs Yes+600
3u
Action Pod NFL Picks
Action Pod NFL Picks
Last 30d: 76-134-0 (+0.2u)
IND o34.5 Team Total+180
1.01u
IND o39.5 Team Total+375
0.27u
TEN +900
0.11u
IND o30.5 Team Total-109
0.92u
Moneyline Hacks
Moneyline Hacks
Last 30d: 124-135-2 (+37.9u)
D.Jones o11.5 Rush Yds-110
1u
🔥Fade the Noise Podcast Ep. 23 LIVE NOW! 🎙️ https://www.youtube.com/@FadetheNoise NEW GUEST Clark! Our VIP Soccer Capper. ⚽️ We break down all the biggest bets of the weekend: 🏈 NFL Week 8 Preview ⚾️ World Series Game 1 Best Pick 🥊 UFC 321 Aspinall vs Gane Main Card Picks 🏆 Best Bets Across 4 Sports! 🔥 Trending Sports News 🗣️ Join our Discord community of 5000 members strong: https://discord.gg/JrzjtqdVfA 📺SUBSCRIBE ON YOUTUBE📺 Podcast also available on Spotify. Tap in & Fade the Noise with us. 📈💰
Gilles Gallant
Gilles Gallant
Last 30d: 31-91-1 (-10.7u)
D.Jones Anytime TD Scorer Yes+260
0.5u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 210-189-2 (-1.7u)
C.Ward o198.5 Pass Yds-115
0.7u
C.Ward o34.5 Pass Att-105
0.57u
Cam Is Money
Cam Is Money
Last 30d: 77-81-1 (-1.4u)
G.Helm o21.5 Rec Yds-115
0.87u
Action Pod NFL Picks
Action Pod NFL Picks
Last 30d: 76-134-0 (+0.2u)
C.Dike Anytime TD Scorer Yes+450
0.22u
Favorite ATD @ChrisRaybon https://myaction.app/spVgtW2PHXb
Over 47.5-105
0.95u
Favorite Total @Stuckey2 https://myaction.app/spVgtW2PHXb
💰🦡 Jake
💰🦡 Jake
Last 30d: 111-115-9 (+12.8u)
C.Ridley Anytime TD Scorer Yes+375
0.3u
Chris Raybon
Chris Raybon
Last 30d: 20-32-1 (-10.8u)
Over 46.5-114
0.88u
No Simmons, Snead for TEN, IND Vance duo on D but getting WRs Downs and Dillon back.
💰🦡 Jake
💰🦡 Jake
Last 30d: 111-115-9 (+12.8u)
C.Ridley Anytime TD Scorer Yes+350
0.1u
Cam Is Money
Cam Is Money
Last 30d: 77-81-1 (-1.4u)
D.Jones u29.5 Pass Att-114
0.88u
FTN Fantasy
FTN Fantasy
Last 30d: 51-49-0 (+4.0u)
IND -14-110
0.91u

Titans vs. Colts Previews & Analysis

  • Titans vs. Colts: Expect Fireworks in AFC South Clash article feature image

    Titans vs. Colts: Expect Fireworks in AFC South Clash

    Stuckey
    Oct 26, 2025 UTC
  • Smart Predictive Model TD Bet (4:25 ET) article feature image

    Smart Predictive Model TD Bet (4:25 ET)

    Alex Kolodziej
    Oct 26, 2025 UTC
  • NFL Best Bets: Spreads, Totals, ML Picks for Sunday article feature image

    NFL Best Bets: Spreads, Totals, ML Picks for Sunday

    Action Network Staff
    Oct 26, 2025 UTC
  • NFL Player Props: 7 Picks for Sunday's Slate article feature image

    NFL Player Props: 7 Picks for Sunday's Slate

    Action Network Staff
    Oct 26, 2025 UTC
See more NFL Coverage Right Arrow

Titans vs. Colts Props

Prop Projections

See All
Right Arrow

There are no prop projections found for the selected slate. Please check back later.

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Titans vs. Colts Public Betting Percentages

Away Logo

Titans

Public

26%

Bets%

74%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Colts
6-34-12-24-22-1
Titans
3-61-32-3N/A3-6

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Colts
5-43-22-23-32-1
Titans
6-34-02-3N/A6-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Colts
7-2N/AN/A5-12-1
Titans
1-8N/AN/AN/A1-8

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 19th@LACW 38-24+2.5 WO 49IND +120
Oct 12thARIW 31-27-8.5 LO 46.5IND -450
Oct 5thLVW 40-6-7.5 WU 46.5IND -370
Sep 28th@LAL 20-27+3.5 LU 49.5LA +154
Sep 21st@TENW 41-20-6 WO 42.5IND -258

Titans vs. Colts Injury Updates

Titans Injuries

  • Calvin Ridley
    WR

    Ridley is out with hamstring

    Out

  • Kevin Winston
    S

    Winston is doubtful with hamstring

    Doubtful

  • Kalel Mullings
    RB

    Mullings is out with ankle

    Out

Colts Injuries

    Team Stats
    341
    Total Yards
    420
    67
    Total Plays
    52
    5.1
    Yards Per Play
    8.1
    259
    YDS
    272
    22/38
    Comps/Atts
    21/31
    5.429
    YPA
    7.529
    1/1
    TDs/INTs
    3/0
    4/31
    Sacks/Yards
    3/16
    113
    Rush Yards
    164
    25
    Attempts
    18
    4.52
    YPC
    9.111
    1
    TDs
    2

    Turnovers

    0
    Fumbles Lost
    0
    1
    Interceptions
    0

    Efficiency

    2/3 66.67%
    Redzone
    3/4 75%
    6/15 0%
    3rd Down
    3/9 0%
    1/3 0%
    4th Down
    1/1 0%

    First Downs

    20
    Total
    21
    13
    Pass
    14
    5
    Rush
    7
    2
    Penalty
    0
    3/34
    Penalties/Yards
    3/32
    34:21
    Possession
    25:39

    Titans vs. Colts Odds Comparison

    Right Arrow

    Could not load odds

    Titans at Colts Team Totals

    MatchupOverUnder
    Titans
    1-8
    o16.5-110
    u16.5-117
    Colts
    7-2
    o32-108
    u32-120