Colts vs. Chargers Odds & Betting Predictions - October 19, 2025
Colts at Chargers
8:05 pm • CBSColts at Chargers Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Colts 7-1 | +6 | +2.5-106 | o49-110 | +120 |
Chargers 5-3 | u45.5 | -2.5-113 | u49.5-112 | -142 |

SoFi StadiumInglewood
Colts vs. Chargers Expert Picks
Mjaybrod
Last 30d: 81-101-0 (-12.0u)
Under 58.5 (Live)-110
0.5u
VegasIsMyBitch
Last 30d: 12-9-1 (+0.9u)
IND +130
0.65u
Matt Moore
Last 30d: 40-46-0 (-2.5u)
LAC -2.5-111
0.55u
Top Shelf Action 🥃
Last 30d: 194-187-1 (-14.8u)
T.Warren 60+ Receiving Yards Yes+108
0.97u
K.Vidal o13.5 Rec Yds-110
0.91u
Prop Bomb 🏝
Last 30d: 1-4-0 (-3.9u)
D.Jones o15.5 Rush Yds-112
1.12u
One glaring trend: the Chargers are leaking QB rushing yards because of how they play defense. They live in light coverage shells and rush four, trying to win with pressure without sending extra bodies. That consistently squeezes the pocket without actually closing lanes, so when the QB bails he’s running into space instead of traffic.
The Chargers have already allowed 23 QB scrambles for 187 yards and 9 first downs, that league-high scramble volume (13.8%) is a direct product of their 2-3-6 and 3-3-5 shells generating pressure without lane integrity. We’ve already seen the exact archetype punish this three straight weeks: Mahomes 57, Bo Nix 33, Geno 20. None of those were designed runs, they were “nothing there, pull it and go.” PropsMadness has that archetype undefeated vs this defense with a large over-margin.
Jones fits the same archetype. He doesn’t need scheme to hand him yards — he runs when the door opens. With how the Chargers rush, two clean escapes can clear this number. The only way this loses is if he never leaves structure or converts those same lanes into sacks instead of yards. #PlayerProps
Vegas Refund
Last 30d: 35-34-1 (-2.5u)
LAC -128
1.28u
Top Shelf Action 🥃
Last 30d: 194-187-1 (-14.8u)
C.Dicker o7.5 Kicking Pts-115
0.9u
Wags Wins
Last 30d: 216-213-1 (-9.9u)
LAC -125
1.5u
Royals Props
Last 30d: 31-18-2 (+9.3u)
M.Pittman o49.5 Rec Yds-114
1u
YBK Picks.com
Last 30d: 64-38-3 (+47.2u)
LAC -2.5-105
2u

Chris Raybon
Last 30d: 18-31-1 (-11.7u)
T.Warren o57.5 Rec Yds-114
0.88u
Chris Gimino
Last 30d: 27-43-1 (-17.0u)
A.Pierce o2.5 Recs-102
0.98u
Matt DiLeo
Last 30d: 41-37-0 (-2.1u)
Both Teams To Make 33+ Yard FG -120
0.83u
Picks Office
Last 30d: 120-98-4 (+15.3u)
IND +2.5-110
0.91u
X: PicksOffice
Cam Is Money
Last 30d: 74-79-1 (-1.4u)
A.Mitchell Anytime TD Scorer Yes+500
0.4u
J.Taylor o88.5 Rush Yds-110
0.91u
IND +2-105
0.95u
💰🦡 Jake
Last 30d: 104-120-8 (+0.2u)
Under 48.5-110
1.1u
Matt DiLeo
Last 30d: 41-37-0 (-2.1u)
D.Jones o14.5 Rush Yds-114
1u
Will Brinson
Last 30d: 10-13-1 (-2.5u)
LAC -1.5-111
1.11u
TAN Pod Touchdown Show
Last 30d: 20-73-2 (-7.7u)
O.Gadsden Anytime TD Scorer Yes+285
1.43u
@The_Oddsmaker https://myaction.app/MsfxZEmqyXb
J.Taylor 2+ TDs Yes+310
1.55u
@The_Oddsmaker https://myaction.app/MsfxZEmqyXb
David Payne
Last 30d: 8-11-0 (-3.5u)
IND +100
1.5u
#SodaBet
Mjaybrod
Last 30d: 81-101-0 (-12.0u)
Under 48.5-110
1u
Obvious over soars under
Grant Neiffer
Last 30d: 38-82-0 (+9.0u)
K.Allen Anytime TD Scorer Yes+210
1.05u
Q.Johnston Anytime TD Scorer Yes+190
0.95u
Gilles Gallant
Last 30d: 27-86-1 (-14.4u)
J.Taylor 2+ TDs Yes+350
1.75u
Ryan Sura
Last 30d: 89-101-1 (-8.7u)
LAC -125
1.25u
Sandy Plashkes
Last 30d: 96-99-1 (+0.6u)
LAC -130
1.3u
The Favorites Podcast
Last 30d: 8-13-0 (-3.9u)
LAC -130
1.3u
@Stuckey2 https://myaction.app/4ocNrlaxxXb
Action Pod NFL Picks
Last 30d: 59-118-0 (-3.3u)
LAC -1.5-112
1u
@sundaysixpack @Stuckey2 https://myaction.app/AOwwgtQewXb
Sunday Six Pack
Last 30d: 11-13-0 (-3.4u)
LAC -1.5-111
1.11u
@Stuckey2 2 https://myaction.app/IHUc2sI9vXb
Boomer Betz
Last 30d: 170-173-2 (+4.6u)
M.Pittman o51.5 Rec Yds-110
0.91u
💰🦡 Jake
Last 30d: 104-120-8 (+0.2u)
K.Vidal Anytime TD Scorer Yes+100
0.1u
Stuck 🚨
Last 30d: 53-60-0 (-1.4u)
LAC -125
0.6u
Boomer Betz
Last 30d: 170-173-2 (+4.6u)
LAC -108
1u
Bet105
Colts vs. Chargers Previews & Analysis
Colts vs. Chargers Props
Prop Projections
There are no prop projections found for the selected slate. Please check back later.
Prop Odds Comparison
Line Movement Tracker
Colts vs. Chargers Public Betting Percentages
Betting Trends
- Chargers are 3-2 in their last 5 games.
- Chargers are 2-3 in their last 5 games against the spread
- Chargers are 1-2 in their road games against the spread
- The totals have gone OVER in 2 of Chargers' last 5 games
- The totals have gone OVER in 2 of Chargers' 4 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Chargers vs. Colts Injury Updates

Chargers Injuries
- Najee HarrisRB
Harris is out with achilles
Out
- Hassan HaskinsRB
Haskins is out with hamstring
Out
- Omarion HamptonRB
Hampton is out with ankle
Out

Colts Injuries
Team Stats
Colts vs. Chargers Odds Comparison
Could not load odds
Colts at Chargers Team Totals
MatchupOverUnder | ||
|---|---|---|
Colts 7-1 | o23.5-115 | u23.5-108 |
Chargers 5-3 | o25-116 | u25-106 |




