Colts vs. Chargers Odds & Betting Predictions - October 19, 2025
Colts at Chargers
8:05 pm • CBSColts at Chargers Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Colts 4-1 | +6 | +1.5-110 | o47.5-115 | +105 |
 Chargers 3-2 | u45.5 | -1.5-110 | u47.5-105 | -122 |
SoFi StadiumInglewood
Colts vs. Chargers Props
Prop Projections
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Prop Odds Comparison
Line Movement Tracker
Colts vs. Chargers Public Betting Percentages
Betting Trends
- Chargers are 3-2 in their last 5 games.
- Chargers are 3-2 in their last 5 games against the spread
- Chargers are 1-1 in their road games against the spread
- The totals have gone OVER in 1 of Chargers' last 5 games
- The totals have gone OVER in 0 of Chargers' 2 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Chargers vs. Colts Injury Updates
Chargers Injuries
- Will DisslyTE
Dissly is questionable with knee
Questionable
- Najee HarrisRB
Harris is out with achilles
Out
- Omarion HamptonRB
Hampton is out with ankle
Out
Colts Injuries
- Alec PierceWR
Pierce is questionable with concussion
Questionable
- Tyler GoodsonRB
Goodson is questionable with groin
Questionable
Player Stats
- passing yards
Justin Herbert1229pyds - passing touchdownsJustin Herbert8ptd
- rushing yards
Omarion Hampton314ryds - rushing touchdownsOmarion Hampton2rtd
Depth Charts
| Starter | 2ND | 3RD | 4TH | ||
|---|---|---|---|---|---|
| QB | Justin Herbert | Trey Lance | DJ Uiagalelei | ||
| RB | Omarion Hampton | Najee Harris | Kimani Vidal | Hassan Haskins | Nyheim Hines |
| WR | Ladd McConkey | Derius Davis | Luke Grimm | ||
| TE | Will Dissly | Tyler Conklin | Oronde Gadsden | Tucker Fisk | Thomas Yassmin |
| LT | Joe Alt | Jamaree Salyer | |||
| LG | Zion Johnson | Branson Taylor | |||
| C | Bradley Bozeman | Andre James | Josh Kaltenberger | ||
| RG | Mekhi Becton | ||||
| RT | Trey Pipkins | David Sharpe | |||
| RDE | Da'Shawn Hand | Justin Eboigbe | Scott Matlock | ||
| LCB | Donte Jackson | Deane Leonard | |||
| SS | Derwin James | Tony Jefferson | RJ Mickens | ||
| FS | Elijah Molden | Kendall Williamson | |||
| RCB | Cam Hart | Nikko Reed | Benjamin St-Juste | Eric Rogers | |
| P | JK Scott | ||||
| H | JK Scott | ||||
| PR | Derius Davis | Ladd McConkey | KeAndre Lambert-Smith | ||
| KR | Derius Davis | Hassan Haskins | KeAndre Lambert-Smith | ||
| LS | Josh Harris | ||||
| RILB | Daiyan Henley | Junior Colson | Emany Johnson | Marlowe Wax | |
| NB | Tarheeb Still | Ja'Sir Taylor | |||
| ROLB | Khalil Mack | Bud Dupree | Garmon Randolph | ||
| LOLB | Tuli Tuipulotu | Kyle Kennard | Caleb Murphy | ||
| RWR | Keenan Allen | Quentin Johnston | |||
| FB | Scott Matlock | ||||
| LILB | Denzel Perryman | Troy Dye | Del'Shawn Phillips | ||
| DT | Otito Ogbonnia | Naquan Jones | |||
| K | Cameron Dicker | ||||
| LWR | Tre' Harris | KeAndre Lambert-Smith | Jalen Reagor | JaQuae Jackson | |
| NT | Teair Tart | Jamaree Caldwell | TeRah Edwards |
Team Stats
1265
YDS
1177
108/153
Comps/Atts
120/182
8.49
YPA
6.995
6/2
TDs/INTs
8/4
4/34
Sacks/Yards
17/96
Colts vs. Chargers Odds Comparison
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Colts at Chargers Team Totals
MatchupOverUnder | ||
|---|---|---|
Colts 4-1 | N/A | N/A |
Chargers 3-2 | N/A | N/A |