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Titans vs Colts Prediction, Odds, Picks, Week 8 Best Bet

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The Tennessee Titans (1-6) and Indianapolis Colts (6-1) square off in Week 8 on Sunday, Oct. 26. Kickoff is set for 4:25 p.m. ET from Lucas Oil Stadium in Indianapolis, Ind. The game will broadcast live on CBS.

The Colts are 14.5-point favorites over the Titans on the spread (Colts -14.5; -115), with the over/under set at 47.5 (-120o / +100u). Indianapolis is a -1600 moneyline favorite and Tennessee is +900 to pull off the upset.

Let's get into my Titans vs Colts prediction and Week 8 best bet.


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Titans vs Colts Predictions, Picks

  • Titans vs Colts pick: Over 47 (-110)

My Colts vs Titans best bet is on the over. Find the best odds by checking our live NFL odds page.


Titans vs Colts Odds

Titans Logo
Sunday, Oct. 26
4:25 p.m. ET
CBS
Colts Logo
Titans Odds
SpreadTotalMoneyline
+14.5
-105
47.5
-120o / 100u
+900
Colts Odds
SpreadTotalMoneyline
-14.5
-115
47.5
-120o / 100u
-1600
Odds via DraftKings. Get up-to-the-minute NFL odds here.
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Titans vs Colts Preview, Prediction

This AFC South tilt sets up to be a high scoring game.

It's looking like L'Jarius Sneed and Jeffery Simmons aren't going to play, which obviously doesn't bode well for the Titans.

After Simmons went out last week, Tennessee got overrun by the Patriots, who looked like they were able just to do whatever they wanted on the ground. The loss of Simmons is particularly massive as it causes a trickle-down effect.

Not only has Simmons been arguably the most dominant interior defensive lineman in the NFL this year, but there’s not many positive things to say about the rest of the Titans’ defense beyond him.

The good news for the Titans is that their offense looked a bit better last week. They simplified everything for rookie QB Cam Ward, and it has led to some better results.

But even without Will Levis doing questionable things, the Titans still seemingly manage to gift the opposing team a touchdown every week, whether it's a pick-six or a fumble.

On the other side, the Colts’ offense is scoring on everybody. That's a great thing for Shane Steichen’s team as their defense isn't very good.

The secondary is banged up, and it showed last week as the Chargers racked up 475 yards of offense against them despite all of their offensive line injuries.


Titans vs Colts Prediction, Over/Under Analysis

While the second meeting between divisional rivals tends to trend under more times than not — as there's usually some familiarity there — I don't know how the Titans are going to get stops in this game.

There's a good chance we'll see the Colts score at least 30 or 35 points in this spot, and I think the Titans can get to 14 or maybe even 20, which would send this game comfortably over the total of 47.5.

Pick: Over 47 (-110)

Playbook

Spread

I'm not betting either side of the spread in this contest.

Moneyline

I will also be staying away from the moneyline market.

Titans vs Colts Over/Under Prediction

My Colts vs Titans betting prediction is on the over at 47 total points.


Titans vs Colts Betting Trends


Titans vs Colts Viewing Info: Channel, Start Time, Streaming

Location:Lucas Oil Stadium in Indianapolis, Ind.
Date:Sunday, Oct. 26
Time:4:25 p.m. ET
TV / Streaming Options:CBS

Titans vs Colts Weather

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Author Profile
About the Author

Stuckey is a senior betting analyst at Action Network, focusing on college football, college basketball, and the NFL. He hosts The Action Network Podcast and co-hosts the Big Bets on Campus podcast with Collin Wilson and Brett McMurphy. Stuckey was Action Network’s first content hire in 2017, helping launch their award-winning app, and continues to work closely with their development team. A CFA Charterholder, Stuckey has been betting since 2003 and has a background as a derivatives analyst in the financial industry. He holds an MBA from George Washington University.

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