49ers vs. Browns Odds & Betting Predictions - November 30, 2025

49ers at Browns

6:00 pm • CBS
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49ers at Browns Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
49ers
7-4
-6
-6.5-115
o42.5-110
-305
Browns
2-8
u42.5
+6.5-105
u42.5-110
+245
location pinSunday 6:00 p.m.
November 30, 2025
Huntington Bank FieldCleveland

49ers vs. Browns Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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49ers vs. Browns Public Betting Percentages

Away Logo

49ers

Public

100%

Bets%

0%

Money%

NFL Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Browns
4-64-00-51-13-5
49ers
6-51-35-24-22-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Browns
6-42-23-22-04-4
49ers
7-42-25-24-23-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Browns
2-8N/AN/A1-11-7
49ers
7-4N/AN/A5-12-3

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 16thBALL 16-23+7.5 WO 37.5BAL +345
Nov 9th@NYJL 20-27-2 LO 37.5NYJ -130
Oct 26th@NEL 13-32+7 LO 40.5NE +275
Oct 19thMIAW 31-6-2.5 WO 34.5CLE -142
Oct 12th@PITL 9-23+6.5 LU 38PIT +245

Browns vs. 49ers Injury Updates

Browns Injuries

  • DeAndre Carter
    WR

    Carter is out with knee

    Out

  • Mike Hall
    DT

    Hall is out with knee

    Out

  • Dillon Gabriel
    QB

    Gabriel is out with concussion

    Out

49ers Injuries

  • Brandon Aiyuk
    WR

    Aiyuk is out with knee

    Out

  • Jacob Cowing
    WR

    Cowing is out with hamstring

    Out

  • Jordan James
    RB

    James is doubtful with finger

    Doubtful

Player Stats
  • passing yards
    Dillon Gabriel logo
    Dillon Gabriel
    937
    pyds
  • passing touchdowns
    Dillon Gabriel logo
    Dillon Gabriel
    7
    ptd
  • rushing yards
    Quinshon Judkins logo
    Quinshon Judkins
    620
    ryds
  • rushing touchdowns
    Quinshon Judkins logo
    Quinshon Judkins
    5
    rtd
Depth Charts
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Starter2ND3RD4TH
QBDillon GabrielShedeur SandersDeshaun Watson
RBJerome FordQuinshon JudkinsDylan Sampson
WRJamari ThrashDeAndre CarterGage Larvadain
TEDavid NjokuHarold FanninBlake WhiteheartBrenden BatesSal Cannella
LTDawand JonesCornelius Lucas
LGJoel BitonioTeven Jenkins
CEthan PocicLuke Wypler
RGWyatt TellerZak Zinter
RTJack Conklin
LDEAlex WrightIsaiah McGuireJulian OkwaraK.J. Henry
RDEMyles GarrettCameron Thomas
WLBDevin BushJerome BakerWinston Reid
MLBCarson SchwesingerMohamoud DiabateEaston Mascarenas-Arnold
LCBDenzel WardDom Jones
SSGrant DelpitRayshawn JenkinsDonovan McMillon
FSRonnie HickmanChristopher Edmonds
PCorey Bojorquez
HCorey Bojorquez
PRDeAndre CarterGage LarvadainKaden Davis
KRDeAndre CarterKaden Davis
LSRex Sunahara
RWRJerry JeudyIsaiah BondKaden Davis
DTMason GrahamMike HallSam Kamara
LWRCedric Tillman
NTMaliek CollinsShelby HarrisAdin Huntington
KAndre Szmyt
NBMyles Harden
Team Stats
2800
YDS
1593
268/388
Comps/Atts
206/360
7.57
YPA
4.997
20/10
TDs/INTs
9/9
19/137
Sacks/Yards
29/206
1043
Rush Yards
980
295
Attempts
247
3.536
YPC
3.968
8
TDs
6

Turnovers

Fumbles Lost
10
Interceptions
9

Efficiency

25/40 62.5%
Redzone
13/25 52%
63/138 0%
3rd Down
46/145 0%
8/15 0%
4th Down
11/21 0%

First Downs

240
Total
167
152
Pass
82
71
Rush
62
17
Penalty
23
/
Penalties/Yards
/
Possession

49ers vs. Browns Odds Comparison

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49ers at Browns Team Totals

MatchupOverUnder
49ers
7-4
N/A
N/A
Browns
2-8
N/A
N/A