Jaguars vs Cardinals Odds & Live Scores - November 23, 2025

MatchupOpenSpreadTotalMoneyline
Jaguars 7-4	N/A	N/A	N/A
Cardinals 3-8	N/A	N/A	N/A

M.Carter o1.5 Recs-120

1.25u

Michael Carter over 1.5 receptions (-120 at B365, -125 at MGM) Emari Demercado is out, but even without his absence, Carter returned to his role of 30-40% routes run (and actually put up almost 50%) that he had in Weeks 5-7. We can probably conservatively pencil Carter in for around 35% of routes, which would be about 14 routes on QB Jacoby Brissett's projected 39.5-40 dropbacks. Carter has been targeted on 20% of his routes run with Brissett at QB, but that should probably increase here against Jacksonville who allow the eighth-most targets per game to the position. If we project Carter for around 0.225 targets per route, that's closer to 3.15 targets, which, at a 70% catch rate would equate to around 2.2 projected receptions. Notably, Carter has cleared 1.5 receptions in all four games he's run at least 30% of routes, including 3 of 3 with Brissett at QB. I have him more like 64% to clear 1.5 receptions, and I'm probably being a bit conservative with Carter's projected routes run rate. Making this a 1.5u play and also taking 3+ at +250 at 36t for a quarter unit

T.McBride 2+ TDs Yes+700

0.1u

There are a few terrible teams the Jaguars might be worthy of being field-goal favorites against on the road, but the Cardinals definitely aren't one of them. This is just a baffling line and a great spot to buy low on Arizona and sell high on Jacksonville all at once. Arizona was unlucky to run into San Francisco finally getting healthy all at once last week and looked bad, but the Cards have been competitive in nearly every game this season. Jacksonville is riding high after beating up on the Chargers in a dominant win but that game got away from LA with all the injuries in both trenches. On last week alone, the Jaguars look like a playoff contender and the Cardinals look like a rebuilding team, but zoom out and the picture changes drastically. On the season, these teams look like relative equals. In fact, I have them ranked back-to-back in my power ratings, meaning I actually make Arizona the favorite here with home-field advantage factored in. The Cardinals defense is the best unit on the field, even more so as corners Garrett Williams and Will Johnson are getting healthy. Hunter Rallis has that unit playing really good football, and Arizona's offense is missing it's top players in Kyler Murray, James Conner, and Marvin Harrison Jr. but has played better, more cohesive football without them. And for all those injuries, Jacksonville may have even more. The Jaguars' injury report this week feels like almost the entire team. Both RBs, Tuten and Etienne, are in doubt along with Brian Thomas Jr. and Brenton Strange, and there are injuries on both sides in the trenches and to both starting corners too. Those RB injuries could be especially important in this matchup against a sometimes beatable run defense. The Jaguars just aren't good enough to have earned the full key number on the road, and the trends are heavily in favor of Arizona. Trevor Lawrence has been poor as a favorite at 10–15 ATS (40%) and worse against teams below .500 at 7–16 ATS (30%). But it's the team-agnostic trends that are even more convincing here, each telling the same story: buy low on Arizona and sell high on Jacksonville: Teams coming off a 17+ point win as underdogs of a TD or less: 65–121–3 ATS (35%) Teams coming off a 17+ loss against opponents off a 17+ win: 117–80–4 ATS (59%) Home teams since 2010 facing opponents that covered by 26+ points as underdogs the previous week: 40–15–1 ATS (73%) This is a great spot to invest in Arizona and sell Jacksonville. Be sure to get Cardinals +3 while it's available (-110, ESPN Bet), and play the +145 moneyline too. I make Arizona favorites. And while we're here, we may as well keep riding Trey McBride overs - because Jacoby Brissett sure is. McBride has been positively on fire with Brissett, averaging 8.4 catches for 89 yards in five games together with at least one touchdown in every game. The Jaguars allow the second-most fantasy points to TEs, including six scores against their last seven TE1s. Play McBride Anytime TD at +110 (bet365) and touch 2+ TDs too at +700. And though McBride's receptions and yards lines are mostly baked in now, he does have eight, nine, 10, and 10-catch games with Brissett so I'll play 10+ receptions at +220 (bet365). If you like both angles together, that certainly makes sense. McBride to score a touchdown in a Cardinals win is +305 if you want to play both (bet365).

T.McBride 10+ Receptions Yes+220

0.25u

There are a few terrible teams the Jaguars might be worthy of being field-goal favorites against on the road, but the Cardinals definitely aren't one of them. This is just a baffling line and a great spot to buy low on Arizona and sell high on Jacksonville all at once. Arizona was unlucky to run into San Francisco finally getting healthy all at once last week and looked bad, but the Cards have been competitive in nearly every game this season. Jacksonville is riding high after beating up on the Chargers in a dominant win but that game got away from LA with all the injuries in both trenches. On last week alone, the Jaguars look like a playoff contender and the Cardinals look like a rebuilding team, but zoom out and the picture changes drastically. On the season, these teams look like relative equals. In fact, I have them ranked back-to-back in my power ratings, meaning I actually make Arizona the favorite here with home-field advantage factored in. The Cardinals defense is the best unit on the field, even more so as corners Garrett Williams and Will Johnson are getting healthy. Hunter Rallis has that unit playing really good football, and Arizona's offense is missing it's top players in Kyler Murray, James Conner, and Marvin Harrison Jr. but has played better, more cohesive football without them. And for all those injuries, Jacksonville may have even more. The Jaguars' injury report this week feels like almost the entire team. Both RBs, Tuten and Etienne, are in doubt along with Brian Thomas Jr. and Brenton Strange, and there are injuries on both sides in the trenches and to both starting corners too. Those RB injuries could be especially important in this matchup against a sometimes beatable run defense. The Jaguars just aren't good enough to have earned the full key number on the road, and the trends are heavily in favor of Arizona. Trevor Lawrence has been poor as a favorite at 10–15 ATS (40%) and worse against teams below .500 at 7–16 ATS (30%). But it's the team-agnostic trends that are even more convincing here, each telling the same story: buy low on Arizona and sell high on Jacksonville: Teams coming off a 17+ point win as underdogs of a TD or less: 65–121–3 ATS (35%) Teams coming off a 17+ loss against opponents off a 17+ win: 117–80–4 ATS (59%) Home teams since 2010 facing opponents that covered by 26+ points as underdogs the previous week: 40–15–1 ATS (73%) This is a great spot to invest in Arizona and sell Jacksonville. Be sure to get Cardinals +3 while it's available (-110, ESPN Bet), and play the +145 moneyline too. I make Arizona favorites. And while we're here, we may as well keep riding Trey McBride overs - because Jacoby Brissett sure is. McBride has been positively on fire with Brissett, averaging 8.4 catches for 89 yards in five games together with at least one touchdown in every game. The Jaguars allow the second-most fantasy points to TEs, including six scores against their last seven TE1s. Play McBride Anytime TD at +110 (bet365) and touch 2+ TDs too at +700. And though McBride's receptions and yards lines are mostly baked in now, he does have eight, nine, 10, and 10-catch games with Brissett so I'll play 10+ receptions at +220 (bet365). If you like both angles together, that certainly makes sense. McBride to score a touchdown in a Cardinals win is +305 if you want to play both (bet365).

ARI +3-110

1u

There are a few terrible teams the Jaguars might be worthy of being field-goal favorites against on the road, but the Cardinals definitely aren't one of them. This is just a baffling line and a great spot to buy low on Arizona and sell high on Jacksonville all at once. Arizona was unlucky to run into San Francisco finally getting healthy all at once last week and looked bad, but the Cards have been competitive in nearly every game this season. Jacksonville is riding high after beating up on the Chargers in a dominant win but that game got away from LA with all the injuries in both trenches. On last week alone, the Jaguars look like a playoff contender and the Cardinals look like a rebuilding team, but zoom out and the picture changes drastically. On the season, these teams look like relative equals. In fact, I have them ranked back-to-back in my power ratings, meaning I actually make Arizona the favorite here with home-field advantage factored in. The Cardinals defense is the best unit on the field, even more so as corners Garrett Williams and Will Johnson are getting healthy. Hunter Rallis has that unit playing really good football, and Arizona's offense is missing it's top players in Kyler Murray, James Conner, and Marvin Harrison Jr. but has played better, more cohesive football without them. And for all those injuries, Jacksonville may have even more. The Jaguars' injury report this week feels like almost the entire team. Both RBs, Tuten and Etienne, are in doubt along with Brian Thomas Jr. and Brenton Strange, and there are injuries on both sides in the trenches and to both starting corners too. Those RB injuries could be especially important in this matchup against a sometimes beatable run defense. The Jaguars just aren't good enough to have earned the full key number on the road, and the trends are heavily in favor of Arizona. Trevor Lawrence has been poor as a favorite at 10–15 ATS (40%) and worse against teams below .500 at 7–16 ATS (30%). But it's the team-agnostic trends that are even more convincing here, each telling the same story: buy low on Arizona and sell high on Jacksonville: Teams coming off a 17+ point win as underdogs of a TD or less: 65–121–3 ATS (35%) Teams coming off a 17+ loss against opponents off a 17+ win: 117–80–4 ATS (59%) Home teams since 2010 facing opponents that covered by 26+ points as underdogs the previous week: 40–15–1 ATS (73%) This is a great spot to invest in Arizona and sell Jacksonville. Be sure to get Cardinals +3 while it's available (-110, ESPN Bet), and play the +145 moneyline too. I make Arizona favorites. And while we're here, we may as well keep riding Trey McBride overs - because Jacoby Brissett sure is. McBride has been positively on fire with Brissett, averaging 8.4 catches for 89 yards in five games together with at least one touchdown in every game. The Jaguars allow the second-most fantasy points to TEs, including six scores against their last seven TE1s. Play McBride Anytime TD at +110 (bet365) and touch 2+ TDs too at +700. And though McBride's receptions and yards lines are mostly baked in now, he does have eight, nine, 10, and 10-catch games with Brissett so I'll play 10+ receptions at +220 (bet365). If you like both angles together, that certainly makes sense. McBride to score a touchdown in a Cardinals win is +305 if you want to play both (bet365).

ARI +145

0.25u

There are a few terrible teams the Jaguars might be worthy of being field-goal favorites against on the road, but the Cardinals definitely aren't one of them. This is just a baffling line and a great spot to buy low on Arizona and sell high on Jacksonville all at once. Arizona was unlucky to run into San Francisco finally getting healthy all at once last week and looked bad, but the Cards have been competitive in nearly every game this season. Jacksonville is riding high after beating up on the Chargers in a dominant win but that game got away from LA with all the injuries in both trenches. On last week alone, the Jaguars look like a playoff contender and the Cardinals look like a rebuilding team, but zoom out and the picture changes drastically. On the season, these teams look like relative equals. In fact, I have them ranked back-to-back in my power ratings, meaning I actually make Arizona the favorite here with home-field advantage factored in. The Cardinals defense is the best unit on the field, even more so as corners Garrett Williams and Will Johnson are getting healthy. Hunter Rallis has that unit playing really good football, and Arizona's offense is missing it's top players in Kyler Murray, James Conner, and Marvin Harrison Jr. but has played better, more cohesive football without them. And for all those injuries, Jacksonville may have even more. The Jaguars' injury report this week feels like almost the entire team. Both RBs, Tuten and Etienne, are in doubt along with Brian Thomas Jr. and Brenton Strange, and there are injuries on both sides in the trenches and to both starting corners too. Those RB injuries could be especially important in this matchup against a sometimes beatable run defense. The Jaguars just aren't good enough to have earned the full key number on the road, and the trends are heavily in favor of Arizona. Trevor Lawrence has been poor as a favorite at 10–15 ATS (40%) and worse against teams below .500 at 7–16 ATS (30%). But it's the team-agnostic trends that are even more convincing here, each telling the same story: buy low on Arizona and sell high on Jacksonville: Teams coming off a 17+ point win as underdogs of a TD or less: 65–121–3 ATS (35%) Teams coming off a 17+ loss against opponents off a 17+ win: 117–80–4 ATS (59%) Home teams since 2010 facing opponents that covered by 26+ points as underdogs the previous week: 40–15–1 ATS (73%) This is a great spot to invest in Arizona and sell Jacksonville. Be sure to get Cardinals +3 while it's available (-110, ESPN Bet), and play the +145 moneyline too. I make Arizona favorites. And while we're here, we may as well keep riding Trey McBride overs - because Jacoby Brissett sure is. McBride has been positively on fire with Brissett, averaging 8.4 catches for 89 yards in five games together with at least one touchdown in every game. The Jaguars allow the second-most fantasy points to TEs, including six scores against their last seven TE1s. Play McBride Anytime TD at +110 (bet365) and touch 2+ TDs too at +700. And though McBride's receptions and yards lines are mostly baked in now, he does have eight, nine, 10, and 10-catch games with Brissett so I'll play 10+ receptions at +220 (bet365). If you like both angles together, that certainly makes sense. McBride to score a touchdown in a Cardinals win is +305 if you want to play both (bet365).