Giants vs. 49ers Odds & Betting Predictions - September 22, 2023

Giants at 49ers

12:15 am • Amazon Prime Video
12 - 30

Giants at 49ers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Giants
2-8
+10.5-110
o43.5-110
+425
49ers
5-4
-10.5-110
u43.5-114
-575
location pinFriday 12:15 a.m.
September 22, 2023
Levi's StadiumSanta Clara
Giants vs. 49ers Expert Picks
Mjaybrod
Mjaybrod
421d ago
Last 30d: 119-109-0 (+5.5u)
NYG +14.5 (Live)-126
1u
Feel it in my chicken bones
Chris Raybon
Chris Raybon
421d ago
Last 30d: 11-13-2 (-3.2u)
J.Hyatt o9.5 Rec Yds-120
1u
Have him projected for closer to 2 catches and NYG could be trailing late
Sean Koerner
Sean Koerner
421d ago
Last 30d: 32-27-0 (+1.6u)
P.Campbell u29.5 Rec Yds-120
1u
Joe Dellera
Joe Dellera
421d ago
Last 30d: 67-80-1 (-4.5u)
J.Hyatt o49.5 Rec Yds+1125
0.25u
Sure - catch a bomb rook
Nick Giffen
Nick Giffen
421d ago
Last 30d: 41-102-1 (-17.3u)
I.Hodgins o30.5 Rec Yds-110
1.1u
Dale Tanhardt
Dale Tanhardt
421d ago
Last 30d: 17-38-0 (+43.8u)
G.Kittle Anytime TD Scorer+170
2.5u
G.Kittle 2+ TDs+1000
0.5u
G.Kittle 3+ TDs+7400
0.1u
G.Kittle First Touchdown Scorer+800
0.75u
B.Purdy First Touchdown Scorer+1700
0.25u
K.Juszczyk First Touchdown Scorer+3500
0.15u
D.Bellinger First Touchdown Scorer+5000
0.15u
L.Cager First Touchdown Scorer+8000
0.1u
Kyle Murray
Kyle Murray
421d ago
Last 30d: 107-127-1 (-15.0u)
D.Samuel Anytime TD Scorer+110
1.1u
M.Breida o29.5 Rush Yds-125
1u
D.Jones u214.5 Pass Yds-115
0.87u
E.Mitchell Anytime TD Scorer+310
1u
Nick Giffen
Nick Giffen
421d ago
Last 30d: 41-102-1 (-17.3u)
SF u27.5-110
1.1u
Biggest Luck Team Total under of the week. Given on @ActionIsland
G.Kittle u50.5 Rec Yds-110
1.1u
Given on @ActionIsland
Charlie DiSturco
Charlie DiSturco
421d ago
Last 30d: 50-72-2 (-2.2u)
D.Waller Anytime TD Scorer+340
0.3u
Firefighter Bets
Firefighter Bets
421d ago
Last 30d: 66-79-0 (-17.7u)
D.Jones o31.5 Pass Att-108
0.93u
B.Purdy u28.5 Pass Att-120
1u
M.Breida o2.5 Recs+130
1.3u
X.McKinney o5.5 Tackles + Ast+115
1.15u
YBK Picks.com
421d ago
Last 30d: 50-47-1 (+5.0u)
Under 43.5-105
3u
Action Island
Action Island
421d ago
Last 30d: 0-0-0 (+0.0u)
G.Kittle u50.5 Rec Yds-120
1u
@nick_giffen
D.Jones u39.5 Rush Yds-110
0.91u
@GDAWG5000
M.Breida u31.5 Rush Yds-115
0.87u
@The_Oddsmaker
Simon Hunter
Simon Hunter
421d ago
Last 30d: 23-24-0 (-4.5u)
NYG +10.5-110
1u
Over 43.5-110
0.5u
D.Jones Anytime TD Scorer+260
1u
Mjaybrod
Mjaybrod
421d ago
Last 30d: 119-109-0 (+5.5u)
J.Hyatt First Touchdown Scorer+9000
0.1u
Hyatt to the 20, 10, TOUCHDOWN!
M.Breida o2.5 Recs+130
1.3u
Giving it at plus money to scare us off
Charlie DiSturco
Charlie DiSturco
421d ago
Last 30d: 50-72-2 (-2.2u)
D.Samuel o55.5 Rec Yds-110
0.5u
M.Breida o12.5 Rec Yds-110
1.1u
No. 1 back and the receiving back of choice in NY. SF should get plenty of pressure on Daniel Jones which translates to dump offs to RBs - similar to Jaylen Warren vs Browns on MNF SF vs RBs -Warren: 5 rec, 12 yds -Kyren: 6 rec, 48 yds
Mjaybrod
Mjaybrod
421d ago
Last 30d: 119-109-0 (+5.5u)
Over 43.5-110
1u
Gut play, somehow the Giants will score
Green Dot Daily
Green Dot Daily
421d ago
Last 30d: 36-51-0 (-10.0u)
E.Mitchell o29.5 Rush Yds-115
0.87u
@PropBomb
P.Campbell u15.5 Longest Reception-125
0.8u
@The_Oddsmaker
Prop Bomb 🏝
Prop Bomb 🏝
421d ago
Last 30d: 13-10-0 (+2.5u)
E.Mitchell o29.5 Rush Yds-115
1u
Gave out on Green Dot Daily - More workload. Shanahan admitted “We definitely got get Elijah [Mitchell] in there more” - Short week, blowout potential, avg. 40.2 RushYds/g over in 5/7 single digit carry games - NYG lead the league in explosive rush% - 8.5% plays that go for 15+ yards, and are 2nd in yards before contact
Prop Bet Guy
Prop Bet Guy
421d ago
Last 30d: 73-55-0 (+11.4u)
B.Okereke o7.5 Tackles + Ast-145
1u
Full write up: https://www.actionnetwork.com/nfl/nfl-player-props-bet-bobby-okereke-on-thursday-night-football?utm_source=twitter&utm_medium=social&utm_campaign=propbetguy
Sean Koerner
Sean Koerner
421d ago
Last 30d: 32-27-0 (+1.6u)
P.Campbell u15.5 Longest Reception-125
1u
Bet365
Shady Biev
Shady Biev
421d ago
Last 30d: 174-210-2 (-41.3u)
D.Samuel First Touchdown Scorer+650
0.5u
My wife gave me this pick while making love
Over 43.5-110
1.1u
POINTS
The Degenerates
The Degenerates
421d ago
Last 30d: 63-65-2 (-8.2u)
Under 43.5-110
1u
Nicholas Parsons
Nicholas Parsons
421d ago
Last 30d: 0-0-0 (+0.0u)
NYG +10.5-110
3.3u
Nick Martin
Nick Martin
421d ago
Last 30d: 176-282-2 (+8.3u)
D.Waller o4.5 Recs+110
0.5u
DK 1:31.
Joe Dellera
Joe Dellera
421d ago
Last 30d: 67-80-1 (-4.5u)
E.Mitchell o74.5 Rush Yds+1075
0.25u
E.Mitchell o49.5 Rush Yds+300
0.25u
Just give me the alts
E.Mitchell Anytime TD Scorer+250
0.5u
Nick Martin
Nick Martin
421d ago
Last 30d: 176-282-2 (+8.3u)
E.Mitchell o29.5 Rush Yds-115
0.65u
DraftKings 12:37.
Royals Props
Royals Props
421d ago
Last 30d: 59-45-1 (+13.0u)
G.Kittle o42.5 Rec Yds-120
1u
Charlie DiSturco
Charlie DiSturco
421d ago
Last 30d: 50-72-2 (-2.2u)
E.Mitchell o25.5 Rush Yds-130
1u
Best number at PB. Fine with 28.5
Jeremiah Rose
Jeremiah Rose
421d ago
Last 30d: 36-38-1 (+1.6u)
E.Mitchell o26.5 Rush Yds-140
0.14u
Resorts World
Sandy  Plashkes
Sandy Plashkes
421d ago
Last 30d: 117-118-0 (+0.5u)
D.Jones o212.5 Pass Yds-112
$56.00
Charlie DiSturco
Charlie DiSturco
421d ago
Last 30d: 50-72-2 (-2.2u)
D.Samuel Anytime TD Scorer+125
0.63u
Matthew Freedman
Matthew Freedman
421d ago
Last 30d: 3-4-0 (-1.0u)
NYG +10.5-111
1.1u
BetMGM - Projection: +9.5. For more, check out Fantasy Life.
Scott Rickenbach
Scott Rickenbach
421d ago
Last 30d: 76-64-2 (+1.3u)
Under 44-110
0.91u
Sandy  Plashkes
Sandy Plashkes
421d ago
Last 30d: 117-118-0 (+0.5u)
D.Samuel o14.5 Rush Yds-112
$56.00
Shady Biev
Shady Biev
421d ago
Last 30d: 174-210-2 (-41.3u)
D.Waller Anytime TD Scorer+270
1u
Biev 🤝 Waller Coke
Markus Markets
Markus Markets
421d ago
Last 30d: 74-86-2 (+12.6u)
E.Mitchell o26.5 Rush Yds-113
0.88u
Mjaybrod
Mjaybrod
421d ago
Last 30d: 119-109-0 (+5.5u)
B.Okereke o7.5 Tackles + Ast-125
0.8u
Need my coin back from week 1
NYG +10.5-110
1u
Give SF the trophy if they cover tonight
Shady Biev
Shady Biev
421d ago
Last 30d: 174-210-2 (-41.3u)
NYG o16.5-105
1.05u
This hits easily somehow idk tho
E.Mitchell o26.5 Rush Yds-106
1u
Elijah Mitchell Biever
Mjaybrod
Mjaybrod
421d ago
Last 30d: 119-109-0 (+5.5u)
D.Waller o4.5 Recs-110
1u
Biever Ramble POD
Markus Markets
Markus Markets
421d ago
Last 30d: 74-86-2 (+12.6u)
T.Hufanga o4.5 Tackles + Ast-148
1u
Mike Randle
Mike Randle
421d ago
Last 30d: 21-11-0 (+7.6u)
E.Mitchell o28.5 Rush Yds-115
0.87u
Follow all my picks at FTNBets.com!
Scott Pritchard
Scott Pritchard
421d ago
Last 30d: 0-0-0 (+0.0u)
Under 44-109
0.92u
Nick Martin
Nick Martin
421d ago
Last 30d: 176-282-2 (+8.3u)
Under 44-110
0.91u
@The_Oddsmaker
Shady Biev
Shady Biev
421d ago
Last 30d: 174-210-2 (-41.3u)
D.Waller o4.5 Recs+110
2u
Ramble POD 6-0?
ASA Inc
422d ago
Last 30d: 0-0-0 (+0.0u)
SF -10-110
0.91u
Brian Edwards
Brian Edwards
422d ago
Last 30d: 21-22-2 (-3.3u)
SF o13.5 (1H)-140
0.71u
SF o27.5-107
0.93u
Sean Koerner
Sean Koerner
422d ago
Last 30d: 32-27-0 (+1.6u)
Under 44.5-110
1u
Royals Props
Royals Props
422d ago
Last 30d: 59-45-1 (+13.0u)
T.Hufanga o4.5 Tackles + Ast+100
1u
Kevin  Thomas
Kevin Thomas
422d ago
Last 30d: 11-24-0 (-13.7u)
C.McCaffrey u113.5 Rush + Rec Yds-114
1u
SF -10.5-109
0.92u
Gilles Gallant
Gilles Gallant
422d ago
Last 30d: 42-94-1 (-9.2u)
D.Samuel Anytime TD Scorer+130
1.3u
Bet at Bet365. Keeping it simple. CMC TD prices nearly unbettable and Deebo can make something out of nothing. Giants blitz a ton and play man coverage at high rate. Should lend itself well to easy dumpoffs to Deebo.
Mjaybrod
Mjaybrod
422d ago
Last 30d: 119-109-0 (+5.5u)
C.McCaffrey u17.5 Rush Att-125
1u
Tailing token here what’s new
Royals Props
Royals Props
422d ago
Last 30d: 59-45-1 (+13.0u)
D.Slayton o32.5 Rec Yds-110
1.1u
Tanner McGrath
Tanner McGrath
423d ago
Last 30d: 62-65-4 (-10.9u)
SF -10-110
1u
Milly Props
Milly Props
423d ago
Last 30d: 10-5-0 (+5.2u)
D.Jones o31.5 Pass Att-108
0.93u
Markus Markets
Markus Markets
423d ago
Last 30d: 74-86-2 (+12.6u)
B.Purdy u29.5 Pass Att-114
1u
Bruce  Marshall
Bruce Marshall
423d ago
Last 30d: 0-0-0 (+0.0u)
SF -10-111
0.9u
Nick Giffen
Nick Giffen
423d ago
Last 30d: 41-102-1 (-17.3u)
R.Bell Anytime TD Scorer+2000
2u
Riding with my guy @GDAWG5000 on this
Gilles Gallant
Gilles Gallant
423d ago
Last 30d: 42-94-1 (-9.2u)
R.Bell Anytime TD Scorer+2000
2u
Bet at Bet365 on 09/19. Down to +850 at FD and +1000 at DK. Aiyuk questionable. Bell played majority of snaps when he was off field. Giants blitz and play man coverage at high rate which plays into Bell getting potential looks.
Sandy  Plashkes
Sandy Plashkes
423d ago
Last 30d: 117-118-0 (+0.5u)
NYG +10.5-110
$55.00
This one STINKS!
Brandon Anderson
Brandon Anderson
424d ago
Last 30d: 26-59-0 (-6.6u)
SF -10-109
0.92u
Week 3 Hot Read! 🎙 Niners have won 12 straight, 8 by 13+. Giants keep getting thrashed by great teams, can barely beat awful Cards. Worst run D in NFL last year. Blowout city. Grabbing now cuz Saquon injured + NY OL a disaster so I think this line could rise quickly to 13+ for teaser protection.

PRO Insights

Giants logo

Giants

NYG Insights
  • Giants logoThe 49ers have rushed for 2,728 yards since the 2022 season -- sixth-most in NFL. The Giants have allowed 2,737 yards rushing since the 2022 season -- fourth-most in NFL.
TRY FOR FREE
49ers logo

49ers

SF Insights
  • 49ers logoThe Giants have scored on 67% of their drives in late and close games since Week 15 of the 2022 Season -- best in NFL. The 49ers defense has allowed scores on 38% of opponent drives in close and late situations since Week 15 of the 2022 Season -- tied for ninth-worst in NFL.
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Giants vs. 49ers Previews & Analysis

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    Koerner's Updated Pick'em & Confidence Ratings

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  • Action Network's NFL Week 3 Betting Primer (Sunday Update) article feature image

    Action Network's NFL Week 3 Betting Primer (Sunday Update)

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    Sep 24, 2023 UTC
  • Our Best Bets for Giants vs. 49ers Tonight article feature image

    Our Best Bets for Giants vs. 49ers Tonight

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Giants vs. 49ers Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Giants vs. 49ers Public Betting Percentages

100%

Bets%

0%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
49ers
4-53-21-34-5N/A
Giants
3-71-42-20-13-6

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
49ers
5-43-22-25-4N/A
Giants
3-71-42-20-13-6

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
49ers
5-4N/AN/A5-4N/A
Giants
2-8N/AN/A0-12-7

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 17th@LAW 30-23-7.5 LO 45SF -340
Sep 10th@PITW 30-7-1.5 WU 41.5SF -120
Aug 26thLACL 12-23-7.5 LU 38.5LAC -367
Aug 20thDENW 21-20+3.5 WO 40SF +140
Aug 13th@LVL 7-34-4.5 LO 37LV -198

Giants vs. 49ers Injury Updates

Giants Injuries

  • Graham Gano
    K

    Gano is questionable with hamstring

    Questionable

  • Matthew Adams
    LB

    Adams is questionable with calf

    Questionable

  • Gunner Olszewski
    WR

    Olszewski is out with groin

    Out

  • Darius Slayton
    WR

    Slayton is out with concussion

    Out

  • Jason Pinnock
    S

    Pinnock is questionable with abdomen

    Questionable

  • Bryce Ford-Wheaton
    WR

    Ford-Wheaton is out with achilles

    Out

  • Darius Muasau
    LB

    Muasau is questionable with hamstring

    Questionable

49ers Injuries

  • Chris Conley
    WR

    Conley is out with hamstring

    Out

  • Jon Feliciano
    OL

    Feliciano is questionable with knee

    Questionable

  • George Kittle
    TE

    Kittle is questionable with hamstring

    Questionable

  • Charvarius Ward
    CB

    Ward is out with personal

    Out

  • Kevin Givens
    DE

    Givens is out with groin

    Out

  • Brandon Aiyuk
    WR

    Aiyuk is out with leg

    Out

  • Yetur Gross-Matos
    DE

    Gross-Matos is out with knee

    Out

Team Stats
150
Total Yards
441
46
Total Plays
78
3.3
Yards Per Play
5.7
137
YDS
310
22/33
Comps/Atts
25/37
3.457
YPA
7.692
0/1
TDs/INTs
2/0
2/16
Sacks/Yards
2/10
29
Rush Yards
141
11
Attempts
39
2.636
YPC
3.615
1
TDs
1

Turnovers

0
Fumbles Lost
0
1
Interceptions
0

Efficiency

1/1 100%
Redzone
2/5 40%
3/12 0%
3rd Down
9/16 0%
0/0 0%
4th Down
0/0 0%

First Downs

10
Total
26
6
Pass
13
2
Rush
9
2
Penalty
4
6/37
Penalties/Yards
6/71
20:50
Possession
39:10

Giants vs. 49ers Odds Comparison

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Giants at 49ers Team Totals

MatchupOverUnder
Giants
2-8
o15.5-118
u15.5+102
49ers
5-4
o27.5+100
u27.5-122