Chiefs vs. Bills Odds & Betting Predictions - November 17, 2024
Chiefs at Bills
9:25 pm • CBSChiefs at Bills Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Chiefs 4-3 | -1 | +2.5+100 | o47-115 | +125 |
Bills 4-2 | u48 | -2.5-122 | u47-105 | -150 |

Highmark StadiumOrchard Park
Chiefs vs. Bills Expert Picks
Roger Goodell
Last 30d: 47-36-2 (+7.7u)
KC +2.5+100
1u
Gamblers Dream
Last 30d: 3-5-0 (+7.8u)
KC +5.5 (Live)+103
3u
Pressing the Chiefs here. Lots of time for a cover.
Mahomes in the 4th with a perfect record at risk.
Austin Pendergrass
Last 30d: 47-49-1 (-1.7u)
KC +132
1u
Ryan Sura
Last 30d: 97-110-1 (-12.6u)
KC +120
1u
Austin Pendergrass
Last 30d: 47-49-1 (-1.7u)
K.Hunt Anytime TD Scorer Yes-105
1u
Steak Friend
Last 30d: 0-0-0 (+0.0u)
KC +125
1u
Under 46.5-110
1.1u
Picks Office
Last 30d: 100-78-3 (+16.5u)
Over 46.5-110
0.91u
Read full writeup on X: https://x.com/PicksOffice
Chiefs’ offense thrives with Mahomes, Kelce, and Hunt, ranking top ten in yards per game but struggles in pass defense. Bills, led by Allen, excel in scoring, red-zone efficiency, and rushing balance, despite injuries. Both teams consistently hit high point totals, setting up a potential shootout in a clash of dynamic offenses.
Zense
Last 30d: 1-2-0 (-0.7u)
BUF -140
0.71u
Sir Lockselot
Last 30d: 32-63-0 (-19.6u)
KC +114
2u
🔑 Chiefs ML +114 (FanDuel) 2u
I know the chiefs have been playing with fire but I am not not going to bet on Mahomes as an underdog. He’s 12-1-1 as a dog and I’ll take those odds all day.
Gamblers Dream
Last 30d: 3-5-0 (+7.8u)
KC +115
1u
I will always take Mahomes at (+) money.
He wants the perfect season that includes a 3 Peat.
Public is all over Buffalo because they are at home.
Mahomes is comfortable in any environment.
Anders
Last 30d: 8-15-0 (-10.1u)
D.Knox Anytime TD Scorer Yes+290
1u
D.Knox 2+ TDs Yes+3000
0.25u
POD
D.Knox o28.5 Rec Yds-112
0.98u
The Propfessor
Last 30d: 32-54-0 (+0.4u)
K.Hunt o14.5 Rec Yds-120
1.2u
Capper Central
Last 30d: 83-68-0 (+1.5u)
BUF -134
$1492.54
MoneyLineWixted
Last 30d: 0-0-0 (+0.0u)
BUF -125
0.5u
Royals Props
Last 30d: 28-20-0 (+4.0u)
K.Shakir o57.5 Rec Yds-130
1u
Shady Biev
Last 30d: 2-1-0 (+1.0u)
BUF -120
2.5u
BUF -1.5 (1Q)+130
3.9u
BUF -1.5 (3Q)+144
3u
BUF -1.5 (4Q)+134
4.02u
BUF -0.5 (1H)-105
2u
BUF -1.5 (2Q)+112
3u
Steak Friend
Last 30d: 0-0-0 (+0.0u)
M.Hollins o25.5 Rec Yds-110
0.5u
Vegas Refund
Last 30d: 38-31-1 (+4.1u)
KC +2.5-110
1.1u
Dale Tanhardt
Last 30d: 0-0-0 (+0.0u)
N.Gray Anytime TD Scorer Yes+550
3.3u
Andrew A
Last 30d: 0-0-0 (+0.0u)
KC +115
0.87u
Convince Me
Last 30d: 0-0-0 (+0.0u)
Under 46.5-108
1u
@SimonHunterNFL and @nick_giffen
The Faves Five
Last 30d: 0-0-0 (+0.0u)
KC +2.5-112
1.12u
Jeremiah Rose
Last 30d: 33-24-0 (+1.3u)
D.Knox o2.5 Recs-150
1.67u
Boyd
Proptology _
Last 30d: 0-0-0 (+0.0u)
D.Knox o29.5 Rec Yds-110
2u
🔬KC runs 2 high at the 3rd highest rate in the league while Knox has seen a 51.4% boost in yards per route run vs 2 high. Match that with the fact Kincaid is out (Knox hit in 5/L8 without Kincaid) and that KC has allowed leagues high 698 yards to tight, we have a recipe for a hit here
Nick Giffen
Last 30d: 38-65-1 (+1.3u)
Under 46.5-108
1.08u
Sandy Plashkes
Last 30d: 95-104-2 (-6.0u)
Over 46.5-110
1u
Jeremiah Rose
Last 30d: 33-24-0 (+1.3u)
D.Knox o2.5 Recs-140
0.29u
Boyd
Ryan Sura
Last 30d: 97-110-1 (-12.6u)
KC +2.5-110
1.1u
Shady Biev
Last 30d: 2-1-0 (+1.0u)
Under 46-110
1.1u
BUF -2.5-109
1u
The Pick Don
Last 30d: 18-10-0 (+10.1u)
BUF -130
1u
The Degenerate
Last 30d: 0-0-0 (+0.0u)
Under 46.5-112
1u
@gogo_dino Best Bet
Wags Wins
Last 30d: 247-219-1 (+22.6u)
BUF -2-110
$100.00
Jeremiah Rose
Last 30d: 33-24-0 (+1.3u)
D.Knox Anytime TD Scorer Yes+325
0.25u
Babs .
Last 30d: 93-98-3 (+0.4u)
KC +115
1u
This should be a good game, but I think that, once again, the Chiefs will win.
Greg DiNardo
Last 30d: 0-0-0 (+0.0u)
Under 46-110
1.1u
Brandon Kravitz
Last 30d: 62-68-1 (+3.0u)
D.Knox Anytime TD Scorer Yes+230
$10.00
Chris Gimino
Last 30d: 27-41-1 (-11.2u)
D.Hopkins o4.5 Recs+120
1u
Matt DiLeo
Last 30d: 43-30-0 (+6.5u)
K.Hunt o13.5 Rec Yds-113
1u
Gilles Gallant
Last 30d: 27-77-1 (-10.2u)
D.Knox Anytime TD Scorer Yes+330
1u
🎶 Hello Knoxness, My Old Friend…🎶
The Favorites Podcast
Last 30d: 11-11-0 (+0.4u)
KC +2.5-110
1.1u
Exec Decision
Brandon Anderson
Last 30d: 47-76-0 (+4.0u)
T.Kelce o65.5 Rec Yds-110
0.75u
TAN pod / best bets
T.Kelce 8+ Receptions Yes+165
0.5u
Extra Kelce escalator
T.Kelce 10+ Receptions Yes+500
0.25u
TAN pod / best bets
J.Allen o9.5 Rush Att+375
0.94u
TAN pod / best bets
J.Allen o6.5 Rush Att-135
0.74u
TAN pod / best bets
J.Allen o30.5 Rush Yds-115
0.87u
TAN pod / best bets
J.Allen 50+ Rushing Yards Yes+235
0.59u
TAN pod / best bets
Kyle Murray
Last 30d: 63-66-2 (+0.3u)
J.Allen o230.5 Pass Yds-115
1u
Brandon Kravitz
Last 30d: 62-68-1 (+3.0u)
KC +2.5-115
$50.00
Jim Sannes
Last 30d: 16-49-0 (-18.5u)
Over 45.5-110
0.91u
Low wind speeds here and two efficient offenses. Have enough wiggle room where I'd still be okay with the over even if both Dalton Kincaid and Amari Cooper are held out.
Matt Moore
Last 30d: 25-29-0 (-0.0u)
BUF +1-110
2u
PRO Insights
Chiefs
KC Insights
- Featured Insight
The Chiefs have been successful on 54.0% of plays they have run with motion since Week 7 -- best in NFL; the Bills have allowed their opponents to be successful on 49.0% of plays against motion since Week 7 -- 5th-worst in NFL.
TRY FOR FREE
Bills
BUF Insights
- Featured Insight
The Bills have been successful on 47.0% of plays they have run against a base rush this season -- T-9th-best in NFL; the Chiefs have allowed their opponents to be successful on 47.0% of plays with a base rush this season -- T-5th-worst in NFL.
TRY FOR FREE
Chiefs vs. Bills Previews & Analysis
Chiefs vs. Bills Props
Prop Projections
There are no prop projections found for the selected slate. Please check back later.
Prop Odds Comparison
Line Movement Tracker
Chiefs vs. Bills Public Betting Percentages
Betting Trends
- Bills are 4-1 in their last 5 games.
- Bills are 2-3 in their last 5 games against the spread
- Bills are 1-1 in their road games against the spread
- The totals have gone OVER in 3 of Bills' last 5 games
- The totals have gone OVER in 3 of Bills' 4 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Chiefs vs. Bills Injury Updates

Chiefs Injuries

Bills Injuries
- Curtis SamuelWR
Samuel is questionable with ribs
Questionable
- Mitch WishnowskyP
Wishnowsky is out with back
Out
- Tyler BassK
Bass is out with hip
Out
- Joshua PalmerWR
Palmer is out with ankle
Out
- Dalton KincaidTE
Kincaid is questionable with oblique
Questionable
Team Stats
Chiefs vs. Bills Odds Comparison
Could not load odds
Chiefs at Bills Team Totals
MatchupOverUnder | ||
|---|---|---|
Chiefs 4-3 | o22.5-118 | u22.5-102 |
Bills 4-2 | o24.5+100 | u24.5-120 |




