JMU vs. Oregon Odds & Betting Predictions - December 21, 2025

JMU at Oregon

12:30 am • TNT

James Madison Dukes

Oregon Ducks

MatchupOpenSpreadTotalMoneyline
JMU 12-1	+20.5	+21.5-115	o50.5-110	+1060
Oregon 11-1	u50.5	-21.5-105	u50.5-110	-2100

Sunday 12:30 a.m.

December 21, 2025

Autzen StadiumEugene

JMU +21.5-110

1.1u

Maybe these guys aren’t done yet, scheme worked against Louisville and the D is no pushover. Getting Immanuel Bush back would be huge. Scheme up a trick play or two to sneak one past the Oregon defense. Loose team with nothing to lose.

ORE -20.5-110

JMU +21.5-115

2.3u

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Stuckey•
Dec 9, 2025 UTC

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NCAAF Public Betting

Oregon are 4-1 in their last 5 games.
Oregon are 3-2 in their last 5 games against the spread
Oregon are 3-2 in their road games against the spread
The totals have gone OVER in 1 of Oregon' last 5 games
The totals have gone OVER in 4 of Oregon' 7 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Oregon	8-4	5-2	3-2	6-3	1-0
JMU	8-5	4-3	4-2	7-5	1-0

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Oregon	6-6	4-3	2-3	5-4	1-0
JMU	5-8	2-5	3-3	5-7	0-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Oregon	11-1	N/A	N/A	8-1	1-0
JMU	12-1	N/A	N/A	12-0	0-1

date	opponent	score	spread	over/under	moneyline
Nov 29th	@WASH	W 26-14	-6.5 W	U 51.5	ORE -245
Nov 22nd	USC	W 42-27	-10.5 W	O 59.5	ORE -410
Nov 15th	MINN	W 42-13	-26.5 W	O 46.5	ORE -3200
Nov 8th	@IOWA	W 18-16	-4.5 L	U 41.5	ORE -210
Oct 25th	WIS	W 21-7	-31.5 L	U 44.5	-