Broncos vs. Colts Odds & Betting Predictions - September 14, 2025
Broncos at Colts
8:05 pm • CBSBroncos at Colts Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Broncos 1-1 | -3.5 | -1.5-115 | o43.5-108 | -125 |
![]() Colts 2-0 | u44.5 | +1.5-105 | u43.5-112 | +105 |

Lucas Oil StadiumIndianapolis
Broncos vs. Colts Expert Picks

Boomer Betz
Last 30d: 127-140-0 (-3.4u)
IND -150 (Live)
0.67u

Sandy Plashkes
Last 30d: 59-90-2 (-33.5u)
IND +6.5 (Live)-115
1u

💰🦡 Jake
Last 30d: 93-100-8 (-0.8u)
Under 64.5 (Live)-110
1.5u

Nick Giffen
Last 30d: 27-98-0 (+5.9u)
B.Nix o234.5 Pass Yds (Live)-112
0.56u
Live at half
R.Harvey o20.5 Rush Yds (Live)-110
0.55u
Live at half

Mjaybrod
Last 30d: 33-53-0 (-20.7u)
IND +3.5 (Live)-110
0.91u
Roll DJ

Jeremiah Rose
Last 30d: 26-29-3 (+0.1u)
DEN PK-110
0.4u

Allan Lem
Last 30d: 95-99-9 (-8.4u)
Under 43.5-110
0.55u
Scott Rickenbach
Last 30d: 37-57-4 (-25.6u)
DEN -127
1u

The Degenerates
Last 30d: 68-74-1 (-14.2u)
Under 43.5-110
1.1u

Sir Lockselot
Last 30d: 27-60-0 (-42.5u)
IND +110
3.3u
📚Player Profit
🔑 Colts ML +110 (Player Profit) 3u
Riding the Colts and Danny Dimes again here. The Broncos looked BAD in week 1 while the Colts looked like the best team in the NFL. At home again, love this spot for them to get it done. Sharp money coming in on INDY too.
Code: sirlocks for 10% off every deposit at https://www.playerprofit.com/

Vegas Refund
Last 30d: 23-23-0 (-2.7u)
DEN -120
1.2u
YBK Picks.com
Last 30d: 30-42-0 (-32.1u)
IND +2.5-105
1.9u

Roger Goodell
Last 30d: 19-23-0 (-4.6u)
B.Nix o4.5 Rush Att-135
0.75u

💰🦡 Jake
Last 30d: 93-100-8 (-0.8u)
Under 43.5-110
1.65u

Grant Neiffer
Last 30d: 49-130-9 (+30.7u)
B.Nix Anytime TD Scorer Yes+450
0.5u

Capper Central
Last 30d: 103-66-0 (+26.0u)
DEN -1-110
1.1u

Nick Giffen
Last 30d: 27-98-0 (+5.9u)
J.Downs o3.5 Recs-125
0.8u
Good buy-low spot on Downs who saw only 3 targets on 17 routes in Week 1, especially with all the hype around rookie TE Tyler Warren
IND played with a leading game script on 65 of 73 plays, an absurd rate that's not likely to continue, meaning Downs' snap rate should bounce back well over the 49% rate he had in Week 1, closer to to 60%, or even higher as this game should be much closer than Indy's blowout win of Miami
With stud CB Pat Surtain shadowing top WR Michael Pittman, there's reports that Warren will indeed be the focus of this Colts pass game
Could be coachspeak/misdirection
Even if true, Broncos get one of the highest pressure rates in the NFL since start of last year, and had highest rate in Week 1
While not great, Daniel Jones is still a much better passer than Anthony Richardson is under pressure, with a completion percentage more than 10% better than Richardson while under pressure since he entered the league
Jones also throws to his first read less than Richardson, especially under pressure, meaning he'll spread it around more than focus on that first read, which should direct targets away from Warren a bit more.
Last year Downs had 8 targets against DEN, but only 3 receptions thanks to Richardson's inaccuracy. We could expect similar volume as Jones spreads it around a bit more away from his first read (Pittman and Warren led Week 1 first read rates for IND), especially with the Pittman/Surtain shadow situation
Not a monster edge, so just betting 1u to win 0.8u at B365. DK is also playable at -130.

Matt Moore
Last 30d: 7-8-1 (-2.3u)
Under 43.5-112
1.1u

Picks Office
Last 30d: 68-88-6 (-23.6u)
Under 42.5-105
1u

Firefighter Bets
Last 30d: 152-143-0 (+2.1u)
T.Hufanga o6.5 Tackles + Ast-115
0.87u
Gilles Gallant
Last 30d: 13-29-0 (+4.6u)
D.Jones o0.5 Int+120
0.5u
NFL INT Picks - W2 - Kind of breaking my rule here of betting a QB to throw an INT while also betting a Colts TD (Warren) but the odds/matchup is too good to ignore.

Chris Raybon
Last 30d: 14-11-0 (+14.3u)
R.Harvey o27.5 Rush Yds-114
1u

Royals Props
Last 30d: 11-17-0 (-8.3u)
D.Jones o23.5 Rush Yds-114
1.14u
FD
Gilles Gallant
Last 30d: 13-29-0 (+4.6u)
T.Warren Anytime TD Scorer Yes+320
1u
Grabbing this on Thursday before the odds move. Led the team in target share in W1. If Warren scores in W2, we’ll never see odds above +300 again.

Kyle Murray
Last 30d: 47-52-4 (+0.7u)
B.Nix o20.5 Pass Comp+100
1u

Ryan Sura
Last 30d: 68-74-3 (-5.9u)
IND +2.5-120
1u

Kenny Ducey
Last 30d: 18-15-1 (+2.1u)
IND +2.5-110
1u

Ryan Sura
Last 30d: 68-74-3 (-5.9u)
IND +116
0.58u

Action Pod NFL Picks
Last 30d: 17-53-0 (-18.8u)
Under 43.5-110
1u
@wheatonbrando Hot Read https://myaction.app/iiVeeKDkvWb

Brandon Anderson
Last 30d: 8-49-0 (-18.5u)
Under 43.5-110
1u
🔥 Week 2 Hot Read 🔥
Unders were the trend on Sun afternoon, 11-1 under and we should see under money follow
not sure if I was more impressed by Denver D or worried about their O Sunday, but both work in our favor here. Nix inaccurate & indecisive. Den D held Tenn to 7 first downs vs 6 sacks, just 133 yards
colts pull up laughable numbers against the Miami team that looks like it’s already quit but Daniel Jones just bought us a value on this under, which already dropped a point from 44.5. Colts did hold that Miami offense to 111 yards entering the fourth quarter and a shut out till late
Daniel Jones Home unders 25-10 lifetime, 71% to the under, best of any starter

Top Shelf Action 🥃
Last 30d: 129-150-2 (-28.7u)
IND +3-120
0.83u
Broncos vs. Colts Previews & Analysis
Broncos vs. Colts Props
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Broncos vs. Colts Public Betting Percentages
Betting Trends
- Colts are 2-0 in their last 5 games.
- Colts are 2-0 in their last 5 games against the spread
- The totals have gone OVER in 1 of Colts' last 2 games
- The totals have gone OVER in 1 of Colts' 2 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Broncos vs. Colts Injury Updates

Broncos Injuries
- Dre GreenlawLB
Greenlaw is out with quad
Out
- Malcolm RoachDT
Roach is out with calf
Out

Colts Injuries
- Tyler GoodsonRB
Goodson is questionable with elbow
Questionable
Team Stats
Broncos vs. Colts Odds Comparison
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Broncos at Colts Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Broncos 1-1 | o22.5-120 | u22.5-103 |
![]() Colts 2-0 | o20.5-116 | u20.5-107 |