49ers vs. Cardinals Odds & Betting Predictions - January 5, 2025
49ers at Cardinals
9:25 pm • FOX49ers at Cardinals Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 49ers 6-10 | -2.5 | +4-112 | o42.5-110 | +165 |
 Cardinals 7-9 | u46.5 | -4-108 | u42.5-110 | -200 |
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49ers vs. Cardinals Previews & Analysis
49ers vs. Cardinals Props
Prop Projections
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Prop Odds Comparison
Line Movement Tracker
49ers vs. Cardinals Public Betting Percentages
Betting Trends
- Cardinals are 4-1 in their last 5 games.
- Cardinals are 5-0 in their last 5 games against the spread
- Cardinals are 5-3 in their road games against the spread
- The totals have gone OVER in 1 of Cardinals' last 5 games
- The totals have gone OVER in 4 of Cardinals' 8 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
49ers vs. Cardinals Injury Updates
49ers Injuries
- Jon FelicianoOL
Feliciano is questionable with knee
Questionable
- Trent WilliamsT
Williams is out with ankle
Out
- Christian McCaffreyRB
McCaffrey is out with knee
Out
- Charvarius WardCB
Ward is questionable with rest
Questionable
- George OdumS
Odum is out with knee
Out
- Dre GreenlawLB
Greenlaw is out with calf
Out
- Kevin GivensDE
Givens is questionable with groin
Questionable
- Mitch WishnowskyP
Wishnowsky is out with back
Out
- Brandon AiyukWR
Aiyuk is out with leg
Out
- Colton McKivitzOL
McKivitz is questionable with knee
Questionable
- Ben BartchOL
Bartch is out with ankle
Out
- Khalil DavisDT
Davis is questionable with knee
Questionable
- Aaron BanksOL
Banks is out with knee
Out
- Spencer BurfordOL
Burford is out with calf
Out
- Brock PurdyQB
Purdy is out with elbow
Out
- Jordan MasonRB
Mason is out with ankle
Out
- Ji'Ayir BrownS
Brown is questionable with ankle
Questionable
- Robert BealDE
Beal is out with ankle
Out
- Darrell LuterCB
Luter is doubtful with pelvis
Doubtful
- Renardo GreenDB
Green is questionable with neck
Questionable
Cardinals Injuries
- Matt PraterK
Prater is out with knee
Out
- James ConnerRB
Conner is out with knee
Out
- Evan BrownOL
Brown is questionable with neck
Questionable
- Sean Murphy-BuntingCB
Murphy-Bunting is questionable with hand
Questionable
- Jalen ThompsonS
Thompson is questionable with ankle
Questionable
- Jonah WilliamsOL
Williams is questionable with illness
Questionable
- Blake GillikinP
Gillikin is out with foot
Out
- Baron BrowningOLB
Browning is questionable with neck
Questionable
- Roy LopezDE
Lopez is questionable with ankle
Questionable
- Naquan JonesDT
Jones is questionable with elbow
Questionable
- Jesse LuketaOLB
Luketa is out with thigh
Out
- Joey BlountS
Blount is out with ribs
Out
- Paris JohnsonOL
Johnson is out with knee
Out
- Jammie RobinsonS
Robinson is doubtful with knee
Doubtful
- Dante StillsDE
Stills is questionable with back
Questionable
- Emari DemercadoRB
Demercado is out with back
Out
- Trey BensonRB
Benson is out with ankle
Out
- Elijah JonesDB
Jones is out with ankle
Out
- Xavier ThomasDE
Thomas is questionable with back
Questionable
- passing yards
Kyler Murray3609pyds - passing touchdownsKyler Murray17ptd
- rushing yards
James Conner1094ryds - rushing touchdownsJames Conner8rtd
| Starter | 2ND | 3RD | 4TH | ||
|---|---|---|---|---|---|
| QB | Kyler Murray | Clayton Tune | |||
| RB | James Conner | Trey Benson | Emari Demercado | DeeJay Dallas | Tony Jones |
| WR | Greg Dortch | Zay Jones | Andre Baccellia | ||
| TE | Trey McBride | Elijah Higgins | Tip Reiman | Travis Vokolek | |
| LT | Paris Johnson | Kelvin Beachum | Christian Jones | ||
| LG | Evan Brown | Isaiah Adams | |||
| C | Hjalte Froholdt | Trystan Colon | |||
| RG | Will Hernandez | Jon Gaines | |||
| RT | Jonah Williams | Jackson Barton | |||
| LDE | Bilal Nichols | Darius Robinson | Ben Stille | ||
| RDE | Justin Jones | L.J. Collier | Dante Stills | ||
| WLB | Kyzir White | Krys Barnes | Markus Bailey | ||
| MLB | Mack Wilson | Owen Pappoe | |||
| LCB | Sean Murphy-Bunting | Elijah Jones | |||
| SS | Budda Baker | Dadrion Taylor-Demerson | Andre Chachere | Darren Hall | |
| FS | Jalen Thompson | Joey Blount | |||
| RCB | Max Melton | Starling Thomas | |||
| P | Blake Gillikin | ||||
| H | Blake Gillikin | ||||
| PR | Greg Dortch | DeeJay Dallas | Xavier Weaver | Emari Demercado | |
| KR | Greg Dortch | DeeJay Dallas | Xavier Weaver | Emari Demercado | |
| LS | Aaron Brewer | ||||
| LOLB | Dennis Gardeck | Victor Dimukeje | Xavier Thomas | ||
| K | Matt Prater | ||||
| RWR | Michael Wilson | Zach Pascal | Tejhaun Palmer | ||
| LWR | Marvin Harrison | Xavier Weaver | |||
| NT | Roy Lopez | Khyiris Tonga | Naquan Jones | ||
| NB | Garrett Williams | Kei'Trel Clark | Jaden Davis | ||
| ROLB | Zaven Collins | Jesse Luketa |
49ers vs. Cardinals Odds Comparison
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49ers at Cardinals Team Totals
MatchupOverUnder | ||
|---|---|---|
49ers 6-10 | N/A | N/A |
Cardinals 7-9 | N/A | N/A |