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Virginia vs. Louisville Odds & Betting Predictions - October 4, 2025

Virginia at Louisville

7:30 pm • ESPN2

Virginia Cavaliers

0-0
30
30 - 27

Louisville Cardinals

0-0
27

Virginia at Louisville Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Virginia
0-0
+7.5
+6.5-110
o60-110
+195
Louisville
0-0
u59.5
-6.5-115
u60-110
-245
location pinSaturday 7:30 p.m.
October 04, 2025
L&N Federal Credit Union StadiumLouisville
Virginia vs. Louisville Expert Picks
Mjaybrod
Mjaybrod
Last 30d: 23-28-0 (-5.9u)
LOU +220 (Live)
0.5u
Fuck!
Collin Wilson
Collin Wilson
Last 30d: 0-0-0 (+0.0u)
Over 58.5-133
0.67u
Alternate Number at DK
Cam Is Money
Cam Is Money
Last 30d: 127-156-4 (-34.5u)
LOU o33.5 Team Total-125
1u
Allan Lem
Allan Lem
Last 30d: 27-25-0 (-1.7u)
LOU -6.5-110
0.55u
Tailing @Bet_Labs
Sean Zerillo
Sean Zerillo
Last 30d: 161-158-14 (-4.7u)
LOU -6.5-105
0.26u
Bet Labs
Bet Labs
Last 30d: 9-10-0 (-2.3u)
LOU -6.5-115
1.73u
Brian Bitler
Brian Bitler
Last 30d: 94-87-0 (+39.7u)
LOU -6.5-110
3u
Vegas Refund
Vegas Refund
Last 30d: 64-59-0 (+0.5u)
LOU -6.5-110
1.1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 63-78-4 (-5.7u)
LOU -6.5-110
1.1u
Mjaybrod
Mjaybrod
Last 30d: 23-28-0 (-5.9u)
LOU -6.5-110
1u
Red birds take a dookie
Doug Ziefel
Doug Ziefel
Last 30d: 184-157-4 (+12.0u)
C.Morris u267.5 Pass Yds-115
0.5u
Brandon Kravitz
Brandon Kravitz
Last 30d: 70-93-3 (-20.3u)
LOU -6.5-115
0.58u
Fading VA after the win of their season.
New Owner
New Owner
Last 30d: 1-4-0 (-3.4u)
Under 63-110
0.91u
Duck
Duck
Last 30d: 1-1-0 (+0.3u)
UVA +7.5-115
1u
Easy call here. Two evenly matched teams. Lou 2x fortunate to get out of Pitt with a w. I like wahoos to compete here.
Babs .
Babs .
Last 30d: 2-1-0 (-0.7u)
LOU -7-110
1u
New Owner
New Owner
Last 30d: 1-4-0 (-3.4u)
LOU -5.5-110
1u
POD

Virginia vs. Louisville Previews & Analysis

  • Collin Wilson's Week 6 ML Round Robin article feature image

    Collin Wilson's Week 6 ML Round Robin

    Collin Wilson•
    Oct 4, 2025 UTC
  • Your Week 6 NCAAF Betting Cheat Sheet article feature image

    Your Week 6 NCAAF Betting Cheat Sheet

    Pete Ruden•
    Oct 4, 2025 UTC
  • Virginia vs. Louisville: No Hangover for Hoos article feature image

    Virginia vs. Louisville: No Hangover for Hoos

    John Feltman•
    Oct 4, 2025 UTC
  • NCAAF Betting Primer: What to Know for Week 6 article feature image

    NCAAF Betting Primer: What to Know for Week 6

    Road ToCFB•
    Sep 30, 2025 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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No props found

Line Movement Tracker

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Virginia vs. Louisville Public Betting Percentages

Away Logo

Virginia

Public

Home Logo

Louisville

34%

Bets%

66%

Money%

NCAAF Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Louisville		N/AN/AN/AN/AN/A
Virginia		N/AN/AN/AN/AN/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Louisville		N/AN/AN/AN/AN/A
Virginia		N/AN/AN/AN/AN/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Louisville		N/AN/AN/AN/AN/A
Virginia		N/AN/AN/AN/AN/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 27th@PITTW 34-27-6.5 WO 53.5LOU -155
Sep 20thBGSUW 40-17-26.5 LO 50.5LOU -4000
Sep 5thJMUW 28-14-15.5 LU 56.5LOU -690
Aug 30thEKUW 51-17-38.5 LO 56.5LOU -4875
Dec 31st@WASHW 35-34+1 WO 50.5LOU -102
Team Stats

Total

237
Total Yards
383
63
Total Plays
75
3.761904761904762
Yards Per Play
5.1066666666666665

Passing

149
YDS
329
19/31
Comps/Atts
34/48
4.806451612903226
YPA
6.854166666666667
1/0
TDs/INTs
2/1
2/20
Sacks/Yards
5/46

Rushing

88
Rush Yards
54
32
Attempts
27
2.75
YPC
2
1
TDs
1

Turnovers

0
Fumbles Lost
1
0
Interceptions
1

Efficiency

2/2 100%
Redzone
4/4 100%
6/15 0%
3rd Down
7/17 0%
2/3 0%
4th Down
1/2 0%

First Downs

14
Total
26
6
Pass
18
8
Rush
5
0
Penalty
3

Misc

7/68
Penalties/Yards
5/60

Virginia vs. Louisville Odds Comparison

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Could not load odds

See more NCAAF Odds Right Arrow

Virginia at Louisville Team Totals

MatchupOverUnder
Virginia
0-0
N/A
N/A
Louisville
0-0
N/A
N/A