Virginia vs. Louisville Odds & Betting Predictions - October 4, 2025
Virginia at Louisville
7:30 pm • ESPN2Virginia at Louisville Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Virginia 0-0 | +7.5 | +6.5-110 | o60-110 | +195 |
 Louisville 0-0 | u59.5 | -6.5-115 | u60-110 | -245 |
L&N Federal Credit Union StadiumLouisville
Virginia vs. Louisville Expert Picks
Mjaybrod
Last 30d: 28-36-0 (-6.5u)
LOU +220 (Live)
0.5u
Fuck!
Collin Wilson
Last 30d: 0-0-0 (+0.0u)
Over 58.5-133
0.67u
Alternate Number at DK
Cam Is Money
Last 30d: 113-104-2 (+9.3u)
LOU o33.5 Team Total-125
1u
Allan Lem
Last 30d: 57-40-0 (+4.2u)
LOU -6.5-110
0.55u
Tailing @Bet_Labs
Sean Zerillo
Last 30d: 168-165-12 (-9.7u)
LOU -6.5-105
0.26u
Bet Labs
Last 30d: 13-8-0 (+3.9u)
LOU -6.5-115
1.73u
Brian Bitler
Last 30d: 81-81-1 (-1.6u)
LOU -6.5-110
3u
Vegas Refund
Last 30d: 8-8-0 (-1.0u)
LOU -6.5-110
1.1u
💰🦡 Jake
Last 30d: 73-80-2 (-0.6u)
LOU -6.5-110
1.1u
Mjaybrod
Last 30d: 28-36-0 (-6.5u)
LOU -6.5-110
1u
Red birds take a dookie
Doug Ziefel
Last 30d: 288-382-23 (-23.1u)
C.Morris u267.5 Pass Yds-115
0.5u
Brandon Kravitz
Last 30d: 84-106-1 (-19.0u)
LOU -6.5-115
0.58u
Fading VA after the win of their season.
New Owner
Last 30d: 73-85-0 (+9.1u)
Under 63-110
0.91u
Duck
Last 30d: 15-8-0 (+3.5u)
UVA +7.5-115
1u
Easy call here. Two evenly matched teams. Lou 2x fortunate to get out of Pitt with a w. I like wahoos to compete here.
Babs .
Last 30d: 13-18-0 (-7.4u)
LOU -7-110
1u
New Owner
Last 30d: 73-85-0 (+9.1u)
LOU -5.5-110
1u
POD
Virginia vs. Louisville Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Virginia vs. Louisville Public Betting Percentages
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| N/A | N/A | N/A | N/A | N/A |
| N/A | N/A | N/A | N/A | N/A |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| N/A | N/A | N/A | N/A | N/A |
| N/A | N/A | N/A | N/A | N/A |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| N/A | N/A | N/A | N/A | N/A |
| N/A | N/A | N/A | N/A | N/A |
Last 5 Matchups
Team Stats
237
Total Yards
383
63
Total Plays
75
3.761904761904762
Yards Per Play
5.1066666666666665
149
YDS
329
19/31
Comps/Atts
34/48
4.806451612903226
YPA
6.854166666666667
1/0
TDs/INTs
2/1
2/20
Sacks/Yards
5/46
7/68
Penalties/Yards
5/60
Virginia vs. Louisville Odds Comparison
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Virginia at Louisville Team Totals
MatchupOverUnder | ||
|---|---|---|
Virginia 0-0 | N/A | N/A |
Louisville 0-0 | N/A | N/A |