Iowa vs. USC Odds & Betting Predictions - November 15, 2025

Iowa at USC

8:30 pm • BTN
21 - 26

Iowa at USC Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Iowa
8-4
+6.5
+6.5-107
o48.5-111
+192
USC
8-3
u49.5
-6.5-114
u48.5-110
-235
location pinSaturday 8:30 p.m.
November 15, 2025
Los Angeles Memorial ColiseumLos Angeles
Iowa vs. USC Expert Picks
Sandy Plashkes
Sandy Plashkes
Last 30d: 121-141-7 (-25.8u)
USC +190 (Live)
1.9u
Picks Office
Picks Office
Last 30d: 216-171-3 (+29.0u)
Under 48.5-105
0.95u
X: PicksOffice for early access
Scott Rickenbach
Scott Rickenbach
Last 30d: 106-100-0 (-5.5u)
USC -6.5-114
1u
Vegas Refund
Vegas Refund
Last 30d: 35-37-1 (-5.5u)
USC -6.5-110
1.1u
Brian Bitler
Brian Bitler
Last 30d: 90-79-1 (+21.3u)
IOWA +6.5-105
2.86u
Collin Wilson
Collin Wilson
Last 30d: 84-68-0 (+8.3u)
Under 49-118
1u
Project 53 but weather conditions worsening with heavy rain and wind gusts in the double digits
💰🦡 Jake
💰🦡 Jake
Last 30d: 89-115-4 (-19.3u)
Under 48.5-105
1u
Dan Gaspar
Dan Gaspar
Last 30d: 63-51-3 (+5.4u)
T.Hines o14.5 Rec Yds-115
1.15u
Sandy Plashkes
Sandy Plashkes
Last 30d: 121-141-7 (-25.8u)
USC -6.5-110
1.1u
Cam Is Money
Cam Is Money
Last 30d: 128-119-2 (+0.2u)
USC -6-115
1u
Duck
Duck
Last 30d: 205-151-3 (+25.0u)
USC -6.5-115
1.15u

Iowa vs. USC Previews & Analysis

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    Iowa vs. USC: Who Wins On A Mush Field?

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    Nov 15, 2025 UTC
  • Our Parlay for Iowa vs. USC article feature image

    Our Parlay for Iowa vs. USC

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    Nov 15, 2025 UTC
  • Your Week 12 NCAAF Betting Cheat Sheet article feature image

    Your Week 12 NCAAF Betting Cheat Sheet

    Pete Ruden
    Nov 15, 2025 UTC
  • Picks For Oklahoma vs. Alabama & More College Football Week 12 Bets & Parlays! article feature image

    Picks For Oklahoma vs. Alabama & More College Football Week 12 Bets & Parlays!

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See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Iowa vs. USC Public Betting Percentages

Away Logo

Iowa

Public

41%

Bets%

59%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
USC
5-64-21-44-51-1
Iowa
9-34-35-04-34-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
USC
6-54-22-35-41-1
Iowa
5-73-42-34-30-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
USC
8-3N/AN/A8-10-2
Iowa
8-4N/AN/A7-00-4

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 8thNWW 38-17-14.5 WO 54.5USC -662
Nov 1st@NEBW 21-17-4.5 LU 59.5USC -200
Oct 18th@NDL 24-34+10.5 WU 60.5ND +300
Oct 11thMICHW 31-13-3 WU 58.5USC -160
Sep 27th@ILLL 32-34-6.5 LO 62ILL -250
Team Stats

Total

320
Total Yards
360
53
Total Plays
63
6.037735849056604
Yards Per Play
5.714285714285714

Passing

137
YDS
254
13/20
Comps/Atts
23/32
6.85
YPA
7.9375
2/1
TDs/INTs
1/0
0/0
Sacks/Yards
2/13

Rushing

183
Rush Yards
106
33
Attempts
31
5.545454545454546
YPC
3.4193548387096775
1
TDs
2

Turnovers

0
Fumbles Lost
0
1
Interceptions
0

Efficiency

3/3 100%
Redzone
5/5 100%
4/10 0%
3rd Down
5/10 0%
1/2 0%
4th Down
0/1 0%

First Downs

17
Total
21
7
Pass
13
9
Rush
4
1
Penalty
4
6/70
Penalties/Yards
3/30

Iowa vs. USC Odds Comparison

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Iowa at USC Team Totals

MatchupOverUnder
Iowa
8-4
o20.5-120
u20.5-110
USC
8-3
o27.5-115
u27.5-115