USC vs. Illinois Odds & Betting Predictions - September 27, 2025
USC at Illinois
4:00 pm • FOXUSC at Illinois Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() USC 4-1 | -1.5 | -6.5-115 | o62-110 | -250 |
![]() Illinois 4-1 | u56.5 | +6.5-108 | u62-110 | +200 |

Memorial Stadium (Champaign, IL)Champaign
USC vs. Illinois Expert Picks

Sandy Plashkes
Last 30d: 74-104-3 (-10.5u)
USC +120 (Live)
1u

Collin Wilson
Last 30d: 86-59-3 (+13.9u)
USC +3 (Live)-110
0.5u

Mjaybrod
Last 30d: 68-84-3 (-10.1u)
USC -3.5 (Live)-108
1u
Easy bet here

VegasIsMyBitch
Last 30d: 9-14-0 (-3.0u)
Over 62-109
0.46u

Jeremiah Rose
Last 30d: 34-38-1 (-2.4u)
ILL +7-115
0.35u

Collin Wilson
Last 30d: 86-59-3 (+13.9u)
ILL +7-115
1u
Coming back live on USC with a slow start

Sandy Plashkes
Last 30d: 74-104-3 (-10.5u)
USC -6.5-115
1.15u

Ryan Sura
Last 30d: 99-94-2 (+7.7u)
ILL +3.5 (1H)-115
1u

The Degenerates
Last 30d: 72-62-2 (+4.9u)
ILL +6.5-105
1u

Dan Gaspar
Last 30d: 21-23-7 (-4.0u)
K.Feagin u0.5 Recs+140
1u

Moneyline Hacks
Last 30d: 118-133-5 (+48.7u)
J.Maiava o8.5 Rush Yds-114
1u
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Babs .
Last 30d: 79-70-1 (+8.9u)
Under 61.5-115
1u
USC vs. Illinois Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
USC vs. Illinois Public Betting Percentages
Betting Trends
- Illinois are 4-1 in their last 5 games.
- Illinois are 4-1 in their last 5 games against the spread
- Illinois are 1-1 in their road games against the spread
- The totals have gone OVER in 3 of Illinois' last 5 games
- The totals have gone OVER in 1 of Illinois' 3 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
364
YDS
331
30/43
Comps/Atts
21/27
8.465116279069768
YPA
12.25925925925926
2/1
TDs/INTs
3/0
1/10
Sacks/Yards
1/8
USC vs. Illinois Odds Comparison
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USC at Illinois Team Totals
MatchupOverUnder | ||
---|---|---|
![]() USC 4-1 | o34.5-114 | u34.5-114 |
![]() Illinois 4-1 | o27.5-114 | u27.5-108 |