USC vs. Illinois Odds & Betting Predictions - September 27, 2025
USC at Illinois
4:00 pm • FOXUSC at Illinois Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 USC 9-4 | -1.5 | -6.5-115 | o62-110 | -250 |
 Illinois 9-4 | u56.5 | +6.5-108 | u62-110 | +200 |
Gies Memorial Stadium (Champaign, IL)Champaign
USC vs. Illinois Expert Picks
Sandy Plashkes
Last 30d: 86-84-5 (-7.8u)
USC +120 (Live)
1u
Collin Wilson
Last 30d: 4-7-1 (-2.1u)
USC +3 (Live)-110
0.5u
John Feltman
Last 30d: 54-55-3 (-10.3u)
Over 54 (Live)-118
1.69u
Mjaybrod
Last 30d: 54-52-0 (+10.6u)
USC -3.5 (Live)-108
1u
Easy bet here
VegasIsMyBitch
Last 30d: 18-15-0 (+2.4u)
Over 62-109
0.46u
Jeremiah Rose
Last 30d: 24-14-1 (+11.1u)
ILL +7-115
0.35u
Collin Wilson
Last 30d: 4-7-1 (-2.1u)
ILL +7-115
1u
Coming back live on USC with a slow start
Sandy Plashkes
Last 30d: 86-84-5 (-7.8u)
USC -6.5-115
1.15u
The Degenerates
Last 30d: 108-108-9 (-11.4u)
ILL +6.5-105
1u
John Feltman
Last 30d: 54-55-3 (-10.3u)
Over 60.5-110
4u
Dan Gaspar
Last 30d: 0-0-0 (+0.0u)
K.Feagin u0.5 Recs+140
1u
Babs .
Last 30d: 42-37-0 (+2.2u)
Under 61.5-115
1u
Doug Ziefel
Last 30d: 133-143-1 (+8.0u)
Under 61.5-115
0.58u
USC vs. Illinois Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
USC vs. Illinois Public Betting Percentages
Betting Trends
- Illinois are 3-2 in their last 5 games.
- Illinois are 3-2 in their last 5 games against the spread
- Illinois are 2-3 in their road games against the spread
- The totals have gone OVER in 2 of Illinois' last 5 games
- The totals have gone OVER in 1 of Illinois' 7 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
364
YDS
331
30/43
Comps/Atts
21/27
8.465116279069768
YPA
12.25925925925926
2/1
TDs/INTs
3/0
1/10
Sacks/Yards
1/8
USC vs. Illinois Odds Comparison
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USC at Illinois Team Totals
MatchupOverUnder | ||
|---|---|---|
USC 9-4 | N/A | N/A |
Illinois 9-4 | N/A | N/A |