Northwestern vs. USC Odds & Betting Predictions - November 8, 2025
Northwestern at USC
2:00 am • FOXNorthwestern at USC Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Northwestern 5-5 | +16.5 | +14.5-112 | o54.5-108 | +472 |
USC 8-2 | u51.5 | -14.5-108 | u54.5-111 | -662 |

Los Angeles Memorial ColiseumLos Angeles
Northwestern vs. USC Expert Picks
Dan Gaspar
Last 30d: 55-54-2 (-6.4u)
C.Komolafe o72.5 Rush Yds-114
1u
Picks Office
Last 30d: 210-177-4 (+20.4u)
NW +14.5-110
1u
X: PicksOffice
Collin Wilson
Last 30d: 83-63-0 (+13.8u)
USC -14-112
1u
Babs .
Last 30d: 97-99-1 (-5.5u)
Over 50.5-118
0.85u
Lines at Lunch
Last 30d: 75-87-5 (-21.7u)
NW +17-130
1.3u
Babs .
Last 30d: 97-99-1 (-5.5u)
NW +17-130
1u
💰🦡 Jake
Last 30d: 86-111-6 (-15.6u)
Under 26.5 (1H)-105
1.58u
Lines at Lunch
Last 30d: 75-87-5 (-21.7u)
Over 51-110
1u
Sandy Plashkes
Last 30d: 115-129-6 (-19.8u)
Over 51-110
1u
Moneyline Hacks
Last 30d: 145-148-2 (+43.5u)
NW +14.5-113
1.5u
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NW +14.5-113
1u
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Duck
Last 30d: 158-122-2 (+17.7u)
NW +14.5-105
1.05u
Northwestern vs. USC Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Northwestern vs. USC Public Betting Percentages
Betting Trends
- USC are 4-1 in their last 5 games.
- USC are 3-2 in their last 5 games against the spread
- USC are 1-3 in their road games against the spread
- The totals have gone OVER in 3 of USC' last 5 games
- The totals have gone OVER in 4 of USC' 6 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 5-5 | 4-2 | 1-3 | 4-5 | 1-0 | |
| 6-3-1 | 5-1 | 1-2-1 | 3-1 | 3-2-1 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 5-5 | 4-2 | 1-3 | 5-4 | 0-1 | |
| 4-5-1 | 2-3-1 | 2-2 | 1-2-1 | 3-3 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 8-2 | N/A | N/A | 8-1 | 0-1 | |
| 5-5 | N/A | N/A | 4-0 | 1-5 |
Last 5 Matchups
Team Stats
150
YDS
309
20/30
Comps/Atts
25/34
5
YPA
9.088235294117647
1/0
TDs/INTs
2/1
2/15
Sacks/Yards
1/9
2/26
Penalties/Yards
4/30
Northwestern vs. USC Odds Comparison
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Northwestern at USC Team Totals
MatchupOverUnder | ||
|---|---|---|
Northwestern 5-5 | o19.5-120 | u19.5-105 |
USC 8-2 | o34.5-110 | u34.5-115 |






