USC vs. Notre Dame Odds & Betting Predictions - October 18, 2025

USC at Notre Dame

11:30 pm • NBC
@

USC at Notre Dame Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
USC
5-1
+10.5
+9.5-110
o61.5-110
+270
Notre Dame
4-2
u53.5
-9.5-110
u61.5-110
-335
location pinSaturday 11:30 p.m.
October 18, 2025
Notre Dame StadiumSouth Bend
thermometer image67°Fahrenheit
rain image49%Rain
wind image7Wind
USC vs. Notre Dame Expert Picks
Collin Wilson
Collin Wilson
Last 30d: 83-65-1 (+6.1u)
J.Price o61.5 Rush Yds-114
0.57u
Full writeup Action Network. Zone read efficiency poor for USC defense. Price best inside/outside rusher in Irish backfield by yards per carry. Averaging 70.3 rushing yards per game
ND o35.5 Team Total-105
1.05u
Full Writeup coming Action Network. Side is inflated w USC injuries on offense. Notre Dame extreme advantages in run concepts. Heavy rain expected early making a sloppy track

USC vs. Notre Dame Previews & Analysis

  • Wilson's Week 8 NCAAF Betting Card article feature image

    Wilson's Week 8 NCAAF Betting Card

    Collin Wilson
    Oct 15, 2025 UTC
  • The College Football Week 8 Group Of 5 Picks You HAVE To Tail! | BBOC Podcast article feature image

    The College Football Week 8 Group Of 5 Picks You HAVE To Tail! | BBOC Podcast

    Mike Calabrese
    Oct 15, 2025 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

USC vs. Notre Dame Public Betting Percentages

Away Logo

USC

Public

69%

Bets%

31%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Notre Dame
3-32-21-13-3N/A
USC
3-33-10-23-3N/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Notre Dame
4-22-22-04-2N/A
USC
4-23-11-14-2N/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Notre Dame
4-2N/AN/A4-2N/A
USC
5-1N/AN/A5-1N/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 11thNCSTW 36-7-23.5 WU 59.5ND -2400
Oct 4thBOISEW 28-7-21.5 LU 63ND -1600
Sep 27th@ARKW 56-13-5.5 WO 63.5ND -218
Sep 20thPURW 56-30-24.5 WO 51ND -4000
Sep 13thTA&ML 40-41-6.5 LO 49.5TA&M -250
Team Stats
1955
YDS
1757
136/186
Comps/Atts
114/169
10.51
YPA
10.4
14/2
TDs/INTs
13/3
4/28
Sacks/Yards
9/74
1359
Rush Yards
1036
213
Attempts
220
6.38
YPC
4.71
19
TDs
17

Turnovers

Fumbles Lost
2
Interceptions
3

Efficiency

31/33 93.9%
Redzone
24/29 82.8%
37/67 0%
3rd Down
33/67 0%
10/12 0%
4th Down
5/14 0%

First Downs

157
Total
143
85
Pass
78
60
Rush
52
12
Penalty
13
/
Penalties/Yards
/

USC vs. Notre Dame Odds Comparison

Right Arrow

Could not load odds

USC at Notre Dame Team Totals

MatchupOverUnder
USC
5-1
N/A
N/A
Notre Dame
4-2
N/A
N/A