Spartans vs. USC Odds & Betting Predictions - September 21, 2025
Spartans at USC
3:00 am • FOXSpartans at USC Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Spartans 4-8 | +14.5 | +18.5-114 | o55.5-110 | +625 |
 USC 9-3 | u56.5 | -18.5-106 | u55.5-110 | -950 |
Los Angeles Memorial ColiseumLos Angeles
Spartans vs. USC Expert Picks
YBK Picks.com
Last 30d: 39-38-0 (-6.0u)
USC -19.5-105
3u
Will Brinson
Last 30d: 22-19-0 (+11.9u)
USC -18.5-110
1.1u
Picks Office
Last 30d: 171-138-2 (+18.0u)
USC -18-110
1u
John Feltman
Last 30d: 70-58-3 (-13.8u)
USC o37.5 Team Total-115
3u
💰🦡 Jake
Last 30d: 76-90-1 (-15.1u)
MSU +10.5 (1H)+100
1u
Big Bets On Campus (CFB)
Last 30d: 63-66-2 (-3.8u)
USC o36.5 Team Total-120
0.83u
@_Collin1 https://myaction.app/V2FMmqguNWb
USC -10 (1H)-110
0.91u
@Stuckey2 https://myaction.app/V2FMmqguNWb
Collin Wilson
Last 30d: 46-31-2 (+11.5u)
USC o37.5 Team Total-114
1u
Massive EPA edge to USC offense, also top 10 Quality and Finishing Drives.
Boomer Betz
Last 30d: 101-112-1 (-19.0u)
MSU +17.5-102
0.98u
Spartans vs. USC Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Spartans vs. USC Public Betting Percentages
Betting Trends
- USC are 4-1 in their last 5 games.
- USC are 3-2 in their last 5 games against the spread
- USC are 1-4 in their road games against the spread
- The totals have gone OVER in 3 of USC' last 5 games
- The totals have gone OVER in 4 of USC' 7 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
Spartans vs. USC Odds Comparison
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Spartans at USC Team Totals
MatchupOverUnder | ||
|---|---|---|
Spartans 4-8 | o18.5-113 | u18.5-112 |
USC 9-3 | o37.5-116 | u37.5-114 |