Iowa vs. Iowa State Odds & Betting Predictions - September 6, 2025
Iowa at Iowa State
4:00 pm • FOXIowa at Iowa State Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Iowa 6-3 | +2 | +3.5-118 | o42.5-115 | +140 |
Iowa State 6-4 | u45.5 | -3.5-110 | u42.5-115 | -170 |

Jack Trice StadiumAmes
Iowa vs. Iowa State Expert Picks
Collin Wilson
Last 30d: 83-68-0 (+11.0u)
Over 37.5 (Live)-110
0.55u
Boomer Betz
Last 30d: 213-199-10 (+14.9u)
IOWA +3.5 (Live)+105
0.53u
The Degenerates
Last 30d: 74-67-1 (+1.9u)
Under 41.5-108
1u
Mjaybrod
Last 30d: 112-107-0 (+8.1u)
ISU u23.5 Team Total-110
0.91u
This is how I tail Biev
Capper Central
Last 30d: 89-72-0 (+4.6u)
IOWA +3.5-110
1u
Sir Lockselot
Last 30d: 22-65-0 (-51.7u)
IOWA +145
3u
📚Player Profit
🔑 Iowa ML +145 (Player Profit) 3u
Getting it going early with a 3u hammer. Iowa’s run-heavy offense plays well against a weak run D in Iowa St. huge rivalry game, spread only 3.5, value in the ML dog. Think Iowa gets it done today on the road
Code: sirlocks for 10% off every purchase at playerprofit.com

Sean Zerillo
Last 30d: 54-82-0 (-2.3u)
IOWA +3.5-110
0.25u
Jeremiah Rose
Last 30d: 21-33-0 (-3.6u)
ISU -2.5-130
0.77u
Big Bets On Campus (CFB)
Last 30d: 40-40-1 (-1.0u)
IOWA +3.5-110
0.91u
@Stuckey2 @_Collin1 https://myaction.app/jBs4sSa5pWb
Brian Bitler
Last 30d: 85-83-2 (-4.7u)
IOWA +3.5-110
2.73u
Collin Wilson
Last 30d: 83-68-0 (+11.0u)
IOWA +3.5-115
1u
As discussed on BBOC Podcast
Allan Lem
Last 30d: 158-113-3 (+14.1u)
B.Eskildsen u37.5 Rec Yds-109
0.55u
Tailing @MrTuttle05
Dan Gaspar
Last 30d: 53-50-4 (-3.8u)
B.Eskildsen u37.5 Rec Yds-109
1.09u
Mike Calabrese
Last 30d: 35-43-0 (+3.8u)
IOWA +130
1u
They didn’t put much on film through the air against Albany and that was on purpose. Iowa State is going to be surprised by Iowa’s passing sophistication. #CyHawk ⚫️🟡🦅
Sandy Plashkes
Last 30d: 105-118-4 (-11.8u)
IOWA +3-110
1.1u
Boomer Betz
Last 30d: 213-199-10 (+14.9u)
IOWA +3.5-118
0.85u
@braydenhenry
Ryan Sura
Last 30d: 80-88-1 (-13.3u)
IOWA +3-110
1.1u
Iowa vs. Iowa State Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Iowa vs. Iowa State Public Betting Percentages
Betting Trends
- Iowa State are 4-1 in their last 5 games.
- Iowa State are 3-2 in their last 5 games against the spread
- Iowa State are 1-3 in their road games against the spread
- The totals have gone OVER in 2 of Iowa State' last 5 games
- The totals have gone OVER in 3 of Iowa State' 5 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 4-6 | 2-3 | 1-3 | 2-5 | 2-1 | |
| 7-2 | 4-2 | 3-0 | 3-2 | 3-0 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 4-6 | 3-2 | 1-3 | 3-4 | 1-2 | |
| 4-5 | 3-3 | 1-2 | 3-2 | 0-3 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 6-4 | N/A | N/A | 4-3 | 2-1 | |
| 6-3 | N/A | N/A | 5-0 | 0-3 |
Last 5 Matchups
Team Stats
214
Total Yards
238
63
Total Plays
57
3.3968253968253967
Yards Per Play
4.175438596491228
83
YDS
134
13/24
Comps/Atts
18/27
3.4583333333333335
YPA
4.962962962962963
0/1
TDs/INTs
1/0
3/17
Sacks/Yards
0/0
4/38
Penalties/Yards
5/42
Iowa vs. Iowa State Odds Comparison
Could not load odds
Iowa at Iowa State Team Totals
MatchupOverUnder | ||
|---|---|---|
Iowa 6-3 | o19.5-126 | u19.5-105 |
Iowa State 6-4 | o23.5-109 | u23.5-121 |






