Iowa vs. Cyclones Odds & Betting Predictions - September 6, 2025

Iowa at Cyclones

4:00 pm • FOX

Iowa Hawkeyes

8-4

13 - 16

Iowa State Cyclones

8-4

MatchupOpenSpreadTotalMoneyline
Iowa 8-4	+2	+3.5-118	o42.5-115	+140
Cyclones 8-4	u45.5	-3.5-110	u42.5-115	-170

Saturday 4:00 p.m.

September 06, 2025

Jack Trice StadiumAmes

Over 37.5 (Live)-110

0.55u

IOWA +3.5 (Live)+105

0.53u

Under 41.5-108

ISU u23.5 Team Total-110

0.91u

This is how I tail Biev

IOWA +3.5-110

IOWA +145

📚Player Profit 🔑 Iowa ML +145 (Player Profit) 3u Getting it going early with a 3u hammer. Iowa’s run-heavy offense plays well against a weak run D in Iowa St. huge rivalry game, spread only 3.5, value in the ML dog. Think Iowa gets it done today on the road Code: sirlocks for 10% off every purchase at playerprofit.com

IOWA +3.5-110

0.25u

ISU -2.5-130

0.77u

IOWA +3.5-110

0.91u

@Stuckey2 @_Collin1 https://myaction.app/jBs4sSa5pWb

IOWA +3.5-110

2.73u

IOWA +3.5-115

As discussed on BBOC Podcast

B.Eskildsen u37.5 Rec Yds-109

0.55u

Tailing @MrTuttle05

B.Eskildsen u37.5 Rec Yds-109

1.09u

IOWA +130

They didn’t put much on film through the air against Albany and that was on purpose. Iowa State is going to be surprised by Iowa’s passing sophistication. #CyHawk ⚫️🟡🦅

IOWA +3-110

1.1u

IOWA +3.5-118

0.85u

@braydenhenry

IOWA +3-110

1.1u

ISU -2.5-105

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See more NCAAF Coverage

No props found

NCAAF Public Betting

Cyclones are 4-1 in their last 5 games.
Cyclones are 3-2 in their last 5 games against the spread
Cyclones are 1-4 in their road games against the spread
The totals have gone OVER in 2 of Cyclones' last 5 games
The totals have gone OVER in 3 of Cyclones' 6 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cyclones	5-7	3-3	1-4	3-6	2-1
Iowa	9-3	4-3	5-0	4-3	4-0

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cyclones	4-8	3-3	1-4	3-6	1-2
Iowa	5-7	3-4	2-3	4-3	0-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cyclones	8-4	N/A	N/A	6-3	2-1
Iowa	8-4	N/A	N/A	7-0	0-4

date	opponent	score	spread	over/under	moneyline
Aug 30th	SDAK	W 55-7	-16.5 W	O 47.5	ISU -850
Aug 23rd	@KSU	W 24-21	+3 W	U 51.5	ISU +125
Dec 28th	@MIA	W 42-41	+5 W	O 62.5	ISU +176
Dec 7th	@ASU	L 19-45	-1.5 L	O 51	ASU -120
Dec 1st	KSU	W 29-21	-2.5 W	U 51.5	ISU -122