Saint Louis vs. Michigan Odds & Betting Predictions - March 21, 2026

Saint Louis at Michigan

4:10 pm • CBS
72 - 95

Saint Louis at Michigan Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Saint Louis
28-5
+13
+12.5-118
o161.5-112
+550
Michigan
31-2
u160.5
-12.5-102
u161.5-110
-800
location pinSaturday 4:10 p.m.
March 21, 2026
KeyBank CenterBuffalo
Saint Louis vs. Michigan Expert Picks
Mjaybrod
Mjaybrod
Last 30d: 88-73-1 (+10.0u)
Under 170.5 (Live)-110
0.91u
Overexposed
SLU u78.5 (Live)-120
0.42u
Not sustainable
John Feltman
John Feltman
Last 30d: 57-54-1 (-2.2u)
SLU +7 (1H)-115
0.58u
Stuck 🚨
Stuck 🚨
Last 30d: 59-74-4 (-0.2u)
SLU +12-110
0.3u
Love tomorrow’s card but hate this one. Played these two small and will look live for some stuff. Hopefully SLU and TAMU outside shots are falling.
Gilles Gallant
Gilles Gallant
Last 30d: 39-52-1 (-4.4u)
E.Cadeau o2.5 Rebs+140
0.7u
#Tailing @nick_giffen
Nick Giffen
Nick Giffen
Last 30d: 40-75-0 (+2.6u)
E.Cadeau o2.5 Rebs+140
1.4u
Threes will be flying, up tempo game, two top 3 eFG% defenses. Should be a few more for cadeau
Allan Lem
Allan Lem
Last 30d: 119-81-2 (+10.3u)
Under 161.5-105
0.53u
The Degenerates
The Degenerates
Last 30d: 111-88-2 (+14.5u)
SLU +12.5-110
1.1u
Jeremiah Rose
Jeremiah Rose
Last 30d: 15-20-0 (-2.2u)
SLU +12.5-115
0.25u
Boyd / FanDuel
Mjaybrod
Mjaybrod
Last 30d: 88-73-1 (+10.0u)
SLU u74.5-110
0.91u
Pissed off wolverine
YBK Picks.com
Last 30d: 30-20-0 (+6.0u)
SLU +12.5-105
1u
Wags Wins
Wags Wins
Last 30d: 265-240-2 (+35.8u)
MICH -11.5-115
1.09u
Cam Is Money
Cam Is Money
Last 30d: 38-38-1 (-4.9u)
MICH -11.5-115
0.87u
Sandy Plashkes
Sandy Plashkes
Last 30d: 120-123-4 (-16.4u)
SLU +12.5-110
1.1u
Player Prop Savant
Player Prop Savant
Last 30d: 102-74-0 (+17.4u)
MICH o86.5-125
1u
Picks Office
Picks Office
Last 30d: 183-200-2 (-30.9u)
MICH -12.5-105
0.95u
Join Discord. All picks posted before 8am https://discord.gg/HjKxYKdSUy
Will Brinson
Will Brinson
Last 30d: 13-24-1 (+8.4u)
MICH -11.5-125
1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 68-77-1 (+2.2u)
MICH -12.5-104
1u
Kendra Middleton
Kendra Middleton
Last 30d: 5-6-0 (-1.3u)
MICH -12.5-110
0.91u
Boomer Betz
Boomer Betz
Last 30d: 116-97-4 (+33.8u)
A.Mara u14.5 Pts+100
$100.00
Doug Ziefel
Doug Ziefel
Last 30d: 143-150-3 (-7.5u)
Under 162-110
0.55u
Mike McNamara
Mike McNamara
Last 30d: 101-129-2 (+4.3u)
SLU +12.5-110
0.4u
SLU +600
0.06u
Dan Gaspar
Dan Gaspar
Last 30d: 39-33-0 (+0.2u)
Y.Lendeborg o6.5 Rebs-135
1.35u
Royals Props
Royals Props
Last 30d: 31-29-0 (-2.5u)
Y.Lendeborg o14.5 Pts-120
1u
Ryan Minion
Ryan Minion
Last 30d: 201-234-2 (-1.1u)
MICH -12-115
$1.00
Boomer Betz
Boomer Betz
Last 30d: 116-97-4 (+33.8u)
MICH -12.5-110
$250.00

Saint Louis vs. Michigan Previews & Analysis

  • +1277 Pace Trend Parlay (Thursday's Hit!) article feature image

    +1277 Pace Trend Parlay (Thursday's Hit!)

    Alex Kolodziej
    Mar 22, 2026 UTC
  • Saint Louis vs Michigan: No. 1 Seed Faces a Tough Test article feature image

    Saint Louis vs Michigan: No. 1 Seed Faces a Tough Test

    Mike McNamara
    Mar 21, 2026 UTC
  • McGrath's Projected Scores for Every NCAA Tournament Second-Round Matchup article feature image

    McGrath's Projected Scores for Every NCAA Tournament Second-Round Matchup

    Tanner McGrath
    Mar 21, 2026 UTC
  • Anderson's Full Saturday NCAA Tournament Betting Card article feature image

    Anderson's Full Saturday NCAA Tournament Betting Card

    Brandon Anderson
    Mar 21, 2026 UTC
See more NCAAB Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Saint Louis vs. Michigan Public Betting Percentages

Away Logo

Saint Louis

Public

49%

Bets%

51%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Michigan
15-189-106-813-181-0
Saint Louis
18-1414-74-717-131-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Michigan
12-217-125-912-190-1
Saint Louis
15-1711-104-714-160-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Michigan
31-2N/AN/A29-21-0
Saint Louis
28-5N/AN/A25-51-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Mar 19thHOWW 101-80-30.5 LO 151.5MICH -20000
Mar 15thPURL 72-80-4.5 LO 149PUR -245
Mar 14thWISW 68-65-12.5 LU 161.5MICH -1000
Mar 13thOSUW 71-67-12.5 LU 155.5MICH -1000
Mar 8thMSUW 90-80-10.5 LO 152.5MICH -577

Michigan vs. Saint Louis Injury Updates

Michigan Injuries

  • Charlie May
    G

    May is out for season with thumb

    Out for Season

  • L.J. Cason
    G

    Cason is out for season with knee

    Out for Season

  • Winters Grady
    G/F

    Grady is out with undisclosed

    Out

Saint Louis Injuries

    Team Stats
    27-61 (44%)
    Field Goals
    34-61 (56%)
    8-15 (53%)
    Free Throws
    16-23 (70%)
    10-32 (31%)
    3P
    11-23 (48%)
    24
    Rebounds
    40
    16
    Assists
    20
    7
    Turnovers
    9
    7
    Steals
    2
    1
    Blocks
    9
    17
    Fouls
    13

    Saint Louis vs. Michigan Odds Comparison

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    Saint Louis at Michigan Team Totals

    MatchupOverUnder
    Saint Louis
    28-5
    N/A
    N/A
    Michigan
    31-2
    N/A
    N/A