Astros vs. Pirates Odds & Betting Predictions - June 5, 2025
Astros at Pirates
10:40 pm • SCHNStarting Pitchers
pitcher | team | era | w-l | |
---|---|---|---|---|
![]() | ![]() | 4.13 | 1-8 | |
![]() | ![]() | 3.07 | 6-4 |
Astros at Pirates Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Astros 34-28 | -1.5 | -1.5+120 | o7.5+101 | -141 |
![]() Pirates 23-40 | u7.5 | +1.5-140 | u7.5-120 | +120 |

PNC ParkPittsburgh
Astros vs. Pirates Expert Picks

Cam Is Money
Last 30d: 106-135-3 (-22.8u)
HOU -115 (Live)
0.43u

YBB SportsData
Last 30d: 9-6-0 (+3.3u)
HOU -145
1u
SDQL SYSTEM (60-44 Record)
#YourBestBet
Scott Rickenbach
Last 30d: 78-75-2 (-9.9u)
HOU -149
0.67u

Top Shelf Action 🥃
Last 30d: 137-157-3 (-2.0u)
HOU -145
1u
Fade dogs off a home shutout win
Overall: 210-87-0,71% (ROI:22%)
Season:9-3-0,75% (ROI:32%)
away favs off a shutout
Overall: 125-58-0,68% (ROI:18%)
Season:8-1-0,89% (ROI:57%)

The Degenerates
Last 30d: 66-72-2 (-18.7u)
Under 7.5-114
1.14u

Picks Office
Last 30d: 77-73-0 (+3.2u)
PIT +135
1u
Follow @PicksOffice on X.
Framber's road ERA jumps to 4.14 – not the same guy outside Houston. Pirates just shut out the Astros, held them to .212 avg. Mitch Keller has a 3.43 ERA in night games – 5 quality starts in May, just no run support. Momentum shift favors PIT at home.
Astros averaging 3.8 runs/game on the road – bottom-tier offense outside Minute Maid. Pirates’ bullpen dialed in – 2.89 ERA over last 3 games. Keller’s 2.50 ERA over his last 3 starts shows he’s keeping games tight. PNC Park = pitcher-friendly, helps suppress big innings.
Pirates better at home (14-17) than road (9-22). Houston just 11-15 away. Back-to-back 3-0 games this series – PIT proven they can shut the door. .
Under 7.5+100
1u
Follow @PicksOffice on X.
Back-to-back 3-0 finals to open the series. Total of just 6 runs in 2 games. Both offenses ice cold – and tonight lines up for another pitcher's duel. Under 7.5 is the sharp look. Pittsburgh’s bats rank dead last in MLB. Houston averages just 3.8 runs on the road.
Valdez: 2.05 ERA over his last 3 starts, but 4.14 ERA away from home. Keller: 2.50 ERA over his last 3 with solid night-game splits (3.43 ERA). Bullpens both sharp – Pirates relievers post a 2.89 ERA over their last 3. PNC Park also suppresses scoring with its pitcher-friendly layout.
Under is 11-3 in PIT's last 14 home games, 8-2 in HOU’s last 10 interleague, and 19-7 in PIT's last 26 overall.

Jim Sannes
Last 30d: 33-50-0 (+1.1u)
F.Valdez o6.5 Ks+124
1.24u
In the alt market on FanDuel. Have Valdez projected for more than seven strikeouts due to his length, efficiency, and matchup. Would just check the weather in Pittsburgh before betting it to ensure the forecast hasn't gotten worse from what it looked like this morning.

Brian Bitler
Last 30d: 90-84-0 (+17.7u)
PIT +135
3u

CeeJ Picks
Last 30d: 27-18-0 (+16.4u)
F.Valdez o5.5 Ks-125
1u
Taken on Novig
Ridiculous value here for Valdez, who has been on an absolute tear and gets a top 4 K-target in the Pirates.
This line is -160 and up on almost every other book, which is why a betting exchange like Novig is HUGE to snipe value like this.
Framber is over this line in 7/12 games on the year, but over his last 6 games, he has caught fire. He has gone 21+ innings in 4/L5 games and just went 27 innings last game vs another top K target, the Rays. He has racked up 6+ Ks in 5/L6 games with his 1 miss being 5 Ks vs SEA.
The Pirates rank 4th in K% on the season vs LHP, and over the last month, they rank 2nd. LHP vs the Pirates have gone over their K props at an astonishing 85%! That's insane. Only 2 LHP pitchers out of 13 haven't gone over their K line against this team.
Framber's last meeting with the Pirates was last season when he struck out 10, and with much of the roster back this year, I expect Framber to have no problem with this lineup yet again.
This is also a potential spot I would ladder or toss in a Ks lotto.

Boomer Betz
Last 30d: 112-149-0 (-29.4u)
F.Valdez u5.5 Hits Allowed-132
1.29u
M.Keller u2.5 Earned Runs-105
1.4u

Sean Zerillo
Last 30d: 135-141-6 (-3.5u)
PIT +138
0.5u
Bet to +125
Astros vs. Pirates Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Astros vs. Pirates Public Betting Percentages
Betting Trends
- Pirates are 2-3 in their last 5 games.
- Pirates are 2-3 in their last 5 games against the spread
- Pirates are 13-18 in their road games against the spread
- The totals have gone OVER in 2 of Pirates' last 5 games
- The totals have gone OVER in 14 of Pirates' 32 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Astros vs. Pirates Injury Updates

Astros Injuries
- Taylor TrammellOF
Trammell is out with calf
Out
- Cristian JavierP
Javier is out with elbow
Out
- Luis GarciaP
Garcia is out with elbow
Out
- Pedro LeonOF
Leon is out with knee
Out
- J.P. FranceP
France is out with shoulder
Out
- Hayden WesneskiP
Wesneski is out with elbow
Out
- Spencer ArrighettiP
Arrighetti is out with thumb
Out

Pirates Injuries
- Johan OviedoP
Oviedo is questionable with elbow
Questionable
- Jared JonesP
Jones is out with elbow
Out
- Jared TrioloIF
Triolo is questionable with back
Questionable
- Spencer HorwitzIF
Horwitz is questionable with wrist
Questionable
Astros vs. Pirates Box Score

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 99 | 7 | 11 | 2 | |
![]() | 15 | 1 | 3 | 0 | |
![]() | 18 | 1 | 2 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 3-5 | 2 | 0 | 1 |
![]() | 2-4 | 2 | 2 | 3 |
![]() | 1-4 | 0 | 0 | 1 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-3 | 1 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 1 |
![]() | 2-4 | 1 | 0 | 2 |
![]() | 0-4 | 0 | 0 | 0 |

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 89 | 6.1 | 5 | 6 | |
![]() | 19 | 1.2 | 1 | 0 | |
![]() | 20 | 1 | 1 | 2 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 1-4 | 0 | 0 | 2 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-2 | 2 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
Astros vs. Pirates Odds Comparison
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Astros at Pirates Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Astros 34-28 | o3.5-150 | u3.5+115 |
![]() Pirates 23-40 | o3.5+110 | u3.5-145 |