Astros vs. Pirates Odds & Betting Predictions - June 4, 2025

Astros at Pirates

10:40 pm • SCHN

Houston Astros

15-23

0 - 3

Pittsburgh Pirates

21-17

pitcher		team	era	w-l
M.Burrows			3.94	2-4
R.Gusto			4.92	7-4

MatchupOpenSpreadTotalMoneyline
Astros 15-23	-1.5	-1.5+125	o9-106	-130
Pirates 21-17	u9	+1.5-149	u9-106	+110

Wednesday 10:40 p.m.

June 04, 2025

PNC ParkPittsburgh

PIT +110

R.Gusto u2.5 Earned Runs-154

0.77u

Going back to targeting this Pirates offense that has ranked bottom-three in many categories and is averaging 3.18 runs per game. They are implied for 4.4 runs today so Vegas likes the matchup against Gusto, who has struggled against lefties this season. He’s going to have to navigate around Cruz, Reynolds and Horwitz but the Pirates have the lowest team ISO in the Majors this season with just 43 homers in 61 games so this is a play against their offense.

HOU -126

0.5u

PIT +115

1.15u

Follow @PicksOffice on X. Gusto’s in freefall – 9.58 ERA, 2.32 WHIP last 3 starts. Got rocked for 13 ER in 3.2 IP vs Tampa. 19 walks in 39 IP shows major control issues. Pirates get a hittable rookie with no confidence. Houston hitting just .221 on the road, .179 vs LHP – massive drop-off away from home. Astros hitting .225 vs RHP on the road. Pittsburgh recently hung 10 runs on Arizona at home, showing clear upside. PNC’s pitching-friendly dimensions + wind could keep the game tight and favor contact bats. Astros’ bullpen bleeding - Historical edge too – PIT 12-7 last 19 home games vs HOU, including a 14-2 and 10-0 beatdown. Pressure on Houston, not PIT – home crowd, looser team, better matchup today.

O.Cruz o1.5 Total Bases+108

1.08u

PIT +112

3.36u

O.Cruz o1.5 Total Bases+110

$1.10

R.Gusto o2.5 Earned Runs+125

1.25u

PIT +120

0.6u

Bet to +110

HOU -1.5+120

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No props found

MLB Public Betting

Pirates are 4-1 in their last 5 games.
Pirates are 3-2 in their last 5 games against the spread
Pirates are 10-8 in their road games against the spread
The totals have gone OVER in 1 of Pirates' last 5 games
The totals have gone OVER in 13 of Pirates' 20 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Pirates	21-17	11-9	10-8	13-9	8-8
Astros	15-23	8-11	7-12	4-11	11-11

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Pirates	20-17-1	13-7	7-10-1	13-9	7-8-1
Astros	24-12-2	14-5	10-7-2	9-6	14-6-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Pirates	21-17	11-9	10-8	14-8	7-9
Astros	15-23	9-10	6-13	5-10	10-12

date	opponent	score	spread	over/under	moneyline
Jun 3rd	HOU	L 0-3	-1.5 L	U 7	HOU -162
Jun 1st	@SD	L 4-6	+1.5 L	O 8.5	SD +127
Jun 1st	@SD	W 5-0	+1.5 W	U 7.5	PIT +191
May 31st	@SD	L 2-3	+1.5 W	U 7.5	SD +160
May 28th	@ARI	W 10-1	+1.5 W	O 7.5	PIT +114

Jake Mangum
LF
Jake Mangum scratched Thursday.
Out
Jared Jones
SP
Jones is out with elbow
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RR.Gusto, P	83	4.1	3	3
LS.Okert, P	14	1.2	1	0
LB.King, P	10	1	2	0
LB.Sousa, P	9	1	1	0

HITTERS	H-AB	R	HR	RBI
1J.Pena, SS	2-4	0	0	0
2I.Paredes, 3B	0-4	0	0	0
3J.Altuve, 2B	1-3	0	0	0
4C.Walker, 1B	0-4	0	0	0
5Y.Diaz, C	2-4	0	0	0
6V.Caratini, DH	1-4	0	0	0
7J.Meyers, CF	1-4	0	0	0
8C.Smith, RF	0-3	0	0	0
9J.Melton, LF	0-3	0	0	0

PITCHER	PC	IP	K
RM.Burrows, P	70	5.1	6
RC.Shugart, P	13	0.2	1
RB.Ashcraft, P	32	2	3
RD.Bednar, P	21	1	2

HITTERS	H-AB	R	RBI
1O.Cruz, CF	2-4	0	0
2A.McCutchen, DH	0-3	0	1
3B.Reynolds, RF	1-3	0	0
4S.Horwitz, 1B	2-3	1	0
5K.Hayes, 3B	1-3	0	0
6A.Frazier, 2B	0-4	0	0
7T.Pham, LF	1-3	1	0
8E.Rodriguez, C	1-3	1	0
9I.Kiner-Falefa, SS	0-3	0	1