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Rams vs. Cardinals Odds & Betting Predictions - December 7, 2025

Rams at Cardinals

9:25 pm • FOX

Los Angeles Rams

8-2
@

Arizona Cardinals

3-7

Rams at Cardinals Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Rams
8-2
N/A
N/A
N/A
Cardinals
3-7
N/A
N/A
N/A
location pinSunday 9:25 p.m.
December 07, 2025
State Farm StadiumGlendale

Rams vs. Cardinals Props

Prop Projections

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Rams vs. Cardinals Public Betting Percentages

Away Logo

Rams

Public

Home Logo

Cardinals

50%

Bets%

50%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Cardinals are 1-4 in their last 5 games.
  • Cardinals are 3-2 in their last 5 games against the spread
  • Cardinals are 4-1 in their road games against the spread
  • The totals have gone OVER in 2 of Cardinals' last 5 games
  • The totals have gone OVER in 4 of Cardinals' 5 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cardinals		5-51-44-11-24-3
Rams		7-33-23-17-20-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cardinals		6-44-12-32-14-3
Rams		4-61-43-13-61-0

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cardinals		3-7N/AN/A2-11-6
Rams		8-2N/AN/A8-10-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 16thSFL 22-41+3.5 LO 48.5SF +157
Nov 9th@SEAL 22-44+7.5 LO 44.5SEA +285
Nov 4th@DALW 27-17+3.5 WU 53.5ARI +145
Oct 19thGBL 23-27+7 WO 44.5GB +270
Oct 12th@INDL 27-31+8.5 WO 46.5IND +350

Rams vs. Cardinals Injury Updates

Rams Injuries

  • Tutu Atwell
    WR

    Atwell is out with hamstring

    Out

Cardinals Injuries

  • Zay Jones
    WR

    Jones is out with achilles

    Out

  • James Conner
    RB

    Conner is out with foot

    Out

  • Kyler Murray
    QB

    Murray is out with foot

    Out

  • Marvin Harrison
    WR

    Harrison is out with appendix

    Out

  • Trey Benson
    RB

    Benson is out with knee

    Out

  • Tip Reiman
    TE

    Reiman is out with ankle

    Out

See more NFL Injuries Right Arrow
Player Stats
  • passing yards
    Jacoby Brissett logo
    Jacoby Brissett
    1570
    pyds
  • passing touchdowns
    Jacoby Brissett logo
    Jacoby Brissett
    10
    ptd
  • rushing yards
    Emari Demercado logo
    Emari Demercado
    241
    ryds
  • rushing touchdowns
    Bam Knight logo
    Bam Knight
    3
    rtd
Depth Charts
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Starter2ND3RD4TH
QBKyler MurrayJacoby Brissett
RBJames ConnerTrey BensonEmari DemercadoMichael CarterZonovan Knight
WRGreg DortchZay JonesAndre Baccellia
TETrey McBrideTip ReimanElijah HigginsTravis VokolekJosiah Deguara
LTParis JohnsonKelvin Beachum
LGEvan Brown
CHjalte FroholdtJon Gaines
RGIsaiah AdamsWill HernandezHayden Conner
RTJonah WilliamsChristian JonesJosh FryarJeremiah Byers
LDECalais CampbellWalter NolenL.J. CollierAnthony Goodlow
RDEDarius RobinsonJustin JonesBilal Nichols
WLBAkeem Davis-GaitherOwen Pappoe
MLBMack WilsonCody SimonJ.J. Russell
LCBWill JohnsonElijah Jones
SSJalen ThompsonDadrion Taylor-Demerson
FSBudda BakerJoey BlountKitan Crawford
RCBMax MeltonDenzel Burke
PBlake Gillikin
HBlake Gillikin
PRGreg DortchXavier Weaver
KRGreg DortchAndre Baccellia
LSAaron Brewer
ROLBJosh SweatBJ OjulariXavier Thomas
LWRMarvin HarrisonSimi FehokoTejhaun Palmer
NTDalvin TomlinsonDante StillsPJ Mustipher
NBGarrett WilliamsKei'Trel ClarkDarren Hall
LOLBBaron BrowningZaven CollinsJordan BurchElliott Brown
RWRMichael WilsonXavier Weaver
KChad Ryland
Team Stats

Passing

2469
YDS
2278
223/339
Comps/Atts
252/375
7.543
YPA
6.752
27/2
TDs/INTs
16/6
14/88
Sacks/Yards
34/254

Rushing

1140
Rush Yards
1057
270
Attempts
241
4.222
YPC
4.386
8
TDs
8

Turnovers

Fumbles Lost
2
Interceptions
6

Efficiency

29/45 64.44%
Redzone
24/42 57.14%
43/111 0%
3rd Down
62/139 0%
13/18 0%
4th Down
6/13 0%

First Downs

227
Total
201
132
Pass
125
69
Rush
58
26
Penalty
18

Misc

/
Penalties/Yards
/
Possession

Rams vs. Cardinals Odds Comparison

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Rams at Cardinals Team Totals

MatchupOverUnder
Rams
8-2
N/A
N/A
Cardinals
3-7
N/A
N/A