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Chargers vs. Cowboys Odds & Betting Predictions - December 21, 2025

Chargers at Cowboys

6:00 pm • FOX

Los Angeles Chargers

8-4
@

Dallas Cowboys

6-6-1

Chargers at Cowboys Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Chargers
8-4
N/A
N/A
N/A
Cowboys
6-6-1
N/A
N/A
N/A
location pinSunday 6:00 p.m.
December 21, 2025
AT&T StadiumArlington

Chargers vs. Cowboys Props

Prop Projections

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Prop Odds Comparison

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Chargers vs. Cowboys Public Betting Percentages

Away Logo

Chargers

Public

Home Logo

Cowboys

50%

Bets%

50%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Cowboys are 2-2 in their last 5 games.
  • Cowboys are 4-1 in their last 5 games against the spread
  • Cowboys are 3-4 in their road games against the spread
  • The totals have gone OVER in 4 of Cowboys' last 5 games
  • The totals have gone OVER in 4 of Cowboys' 6 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cowboys		7-64-23-42-45-2
Chargers		6-64-21-45-61-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cowboys		9-44-25-24-25-2
Chargers		6-63-32-35-61-0

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cowboys		6-6-1N/AN/A3-33-3-1
Chargers		8-4N/AN/A7-41-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Dec 5th@DETL 30-44+3.5 LO 55.5DET +155
Nov 27thKCW 31-28+3.5 WO 53.5DAL +154
Nov 23rdPHIW 24-21+3 WU 48DAL +135
Nov 18th@LVW 33-16-3.5 WO 48.5DAL -199
Nov 4thARIL 17-27-3.5 LU 53.5ARI -175

Cowboys vs. Chargers Injury Updates

Cowboys Injuries

  • Miles Sanders
    RB

    Sanders is out with ankle

    Out

Chargers Injuries

  • Justin Herbert
    QB

    Herbert is questionable with hand

    Questionable

  • Najee Harris
    RB

    Harris is out with achilles

    Out

  • Hassan Haskins
    RB

    Haskins is out with hamstring

    Out

See more NFL Injuries Right Arrow
Player Stats
  • passing yards
    Dak Prescott logo
    Dak Prescott
    3637
    pyds
  • passing touchdowns
    Dak Prescott logo
    Dak Prescott
    26
    ptd
  • rushing yards
    Javonte Williams logo
    Javonte Williams
    1022
    ryds
  • rushing touchdowns
    Javonte Williams logo
    Javonte Williams
    9
    rtd
Depth Charts
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Starter2ND3RD4TH
QBDak PrescottJoe MiltonWill Grier
RBJavonte WilliamsJaydon BluePhil MafahMiles SandersMalik Davis
WRCeeDee LambKaVontae TurpinJalen Cropper
TEJake FergusonLuke SchoonmakerBrevyn Spann-FordRivaldo FairweatherPrinceton Fant
LTTyler GuytonNate Thomas
LGTyler SmithT.J. Bass
CCooper BeebeBrock Hoffman
RGTyler Booker
RTTerence SteeleHakeem AdenijiAjani Cornelius
LDEDonovan EzeiruakuSam WilliamsJames Houston
RDEDante FowlerPayton Turner
WLBDeMarvion OvershownMarist LiufauShemar JamesJustin Barron
MLBKenneth MurrayJack Sanborn
LCBTrevon DiggsCaelen Carson
SSMalik HookerMarkquese BellAlijah Clark
FSDonovan WilsonJuanyeh Thomas
RCBDaRon BlandShavon Revel
PBryan Anger
HBryan Anger
PRKaVontae TurpinJalen TolbertJalen Cropper
KRKaVontae TurpinJalen CropperJaydon Blue
LSTrent Sieg
RWRJalen TolbertTraeshon Holden
DTSolomon ThomasJay Toia
FBHunter Luepke
KBrandon Aubrey
LWRGeorge PickensJonathan MingoRyan Flournoy
NTOsa OdighizuwaPerrion WinfreyEarnest Brown
NBZion ChildressJosh ButlerC.J. Goodwin
Team Stats

Passing

2696
YDS
3581
272/409
Comps/Atts
340/493
7.169
YPA
7.578
21/10
TDs/INTs
27/11
40/236
Sacks/Yards
22/155

Rushing

1465
Rush Yards
1553
323
Attempts
339
4.536
YPC
4.581
7
TDs
13

Turnovers

Fumbles Lost
10
Interceptions
11

Efficiency

21/41 51.22%
Redzone
30/51 58.82%
83/172 0%
3rd Down
70/160 0%
9/15 0%
4th Down
11/20 0%

First Downs

244
Total
304
138
Pass
183
85
Rush
85
21
Penalty
36

Misc

/
Penalties/Yards
/
Possession

Chargers vs. Cowboys Odds Comparison

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Chargers at Cowboys Team Totals

MatchupOverUnder
Chargers
8-4
N/A
N/A
Cowboys
6-6-1
N/A
N/A