49ers vs. Giants Odds & Betting Predictions - November 2, 2025

49ers at Giants

6:00 pm • CBS

San Francisco 49ers

@

New York Giants

MatchupOpenSpreadTotalMoneyline
49ers 4-2	N/A	N/A	N/A
Giants 2-4	N/A	N/A	N/A

location pin

Sunday 6:00 p.m.

November 02, 2025

MetLife StadiumEast Rutherford

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NFL Public Betting

Giants are 1-4 in their last 5 games.
Giants are 2-3 in their last 5 games against the spread
Giants are 1-2 in their road games against the spread
The totals have gone OVER in 1 of Giants' last 5 games
The totals have gone OVER in 1 of Giants' 3 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Giants	3-3	2-1	1-2	N/A	3-3
49ers	3-3	0-2	3-1	2-2	1-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Giants	2-4	1-2	1-2	N/A	2-4
49ers	4-2	1-1	3-1	2-2	2-0

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Giants	2-4	N/A	N/A	N/A	2-4
49ers	4-2	N/A	N/A	3-1	1-1

date	opponent	score	spread	over/under	moneyline
Oct 10th	PHI	W 34-17	+7.5 W	O 40.5	NYG +325
Oct 5th	@NO	L 14-26	+2.5 L	U 41.5	NO +116
Sep 28th	LAC	W 21-18	+6 W	U 42.5	NYG +225
Sep 22nd	KC	L 9-22	+6 L	U 44.5	KC +245
Sep 14th	@DAL	L 37-40	+4.5 W	O 44.5	DAL +194

George Kittle
TE
Kittle is questionable with hamstring
Questionable

Brandon Aiyuk
WR
Aiyuk is out with knee
Out
Jauan Jennings
WR
Jennings is questionable with ribs
Questionable
Brock Purdy
QB
Purdy is questionable with toe
Questionable
Ricky Pearsall
WR
Pearsall is questionable with knee
Questionable
Jacob Cowing
WR
Cowing is out with hamstring
Out
Jordan Watkins
WR
Watkins is doubtful with ankle
Doubtful
Jordan James
RB
James is doubtful with finger
Doubtful

Darius Slayton
WR
Slayton is out with hamstring
Out
Malik Nabers
WR
Nabers is out with knee
Out

See more NFL Injuries

passing yards
Russell Wilson
786
pyds
passing touchdowns
Jaxson Dart
4
ptd
rushing yards
Cam Skattebo
338
ryds
rushing touchdowns
Cam Skattebo
5
rtd

	Starter	2ND	3RD	4TH
QB	Russell Wilson	Jameis Winston	Jaxson Dart
RB	Tyrone Tracy	Devin Singletary	Cam Skattebo	Dante Miller
WR	Wan'Dale Robinson	Ihmir Smith-Marsette	Gunner Olszewski
TE	Theo Johnson	Daniel Bellinger	Chris Manhertz	Thomas Fidone
LT	James Hudson	Joshua Ezeudu
LG	Jon Runyan	Aaron Stinnie	Bryan Hudson
C	John Michael Schmitz	Austin Schlottmann
RG	Greg Van Roten	Evan Neal	Jake Kubas
RT	Jermaine Eluemunor	Marcus Mbow
RDE	Roy Robertson-Harris	Elijah Chatman
LCB	Paulson Adebo	Art Green
SS	Tyler Nubin	Dane Belton
FS	Jevon Holland	Raheem Layne
RCB	Deonte Banks	Cor'Dale Flott
P	Jamie Gillan
H	Jamie Gillan
PR	Ihmir Smith-Marsette	Gunner Olszewski	Dalen Cambre
KR	Ihmir Smith-Marsette	Tyrone Tracy	Devin Singletary
LS	Casey Kreiter
LWR	Malik Nabers	Beaux Collins	Lil'Jordan Humphrey	Da'Quan Felton
RILB	Micah McFadden	Chris Board
LILB	Bobby Okereke	Darius Muasau	Demetrius Flannigan-Fowles
RWR	Darius Slayton	Jalin Hyatt	Dalen Cambre
LOLB	Brian Burns	Chauncey Golston
ROLB	Abdul Carter	Kayvon Thibodeaux	Tomon Fox
DT	Rakeem Nunez-Roches	Darius Alexander	Elijah Garcia
NB	Dru Phillips	Nic Jones	TJ Moore
NT	Dexter Lawrence	D.J. Davidson	Jordon Riley
K	Graham Gano	Jude McAtamney

Total

Passing

1749

YDS

1212

161/241

Comps/Atts

122/197

7.627

YPA

6.569

10/7

TDs/INTs

7/5

13/89

Sacks/Yards

16/82

Rushing

493

Rush Yards

757

161

Attempts

181

3.062

YPC

4.182

1

TDs

7

Turnovers

Fumbles Lost

7

Interceptions

5

Efficiency

9/21 42.86%

Redzone

9/22 40.91%

39/86 0%

3rd Down

32/81 0%

6/10 0%

4th Down

6/14 0%

First Downs

132

Total

126

90

Pass

55

31

Rush

54

11

Penalty

17

Misc

/

Penalties/Yards

/

Possession

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MatchupOverUnder
49ers 4-2	N/A	N/A
Giants 2-4	N/A	N/A