Indiana vs. Ohio State Odds & Betting Predictions - December 7, 2025

Indiana at Ohio State

1:00 am • FOX

Indiana Hoosiers

16-0

13 - 10

Ohio State Buckeyes

12-2

MatchupOpenSpreadTotalMoneyline
Indiana 16-0	+6	+3.5-112	o45.5-110	+150
Ohio State 12-2	u49.5	-3.5-108	u45.5-110	-185

Sunday 1:00 a.m.

December 07, 2025

Lucas Oil StadiumIndianapolis

OSU -125 (Live)

1.25u

IU +7.5 (Live)-125

OSU -170 (Live)

0.25u

OSU -3.5-112

📚Player Profit

IU +4+100

Adding to original position

IU +155

0.78u

IU +4.5-105

2.86u

OSU -4-110

Under 47.5-110

0.91u

Join Discord: https://discord.gg/NcyhmJVXPe

OSU u26.5-105

0.95u

Another

IU +4.5-115

0.3u

Pretty close to market. Smaller gut. https://www.actionnetwork.com/ncaaf/college-football-picks-expert-conference-championship-best-bets-ohio-state-vs-indiana-alabama-vs-georgia

IU +142 (1H)

IU +4.5-110

OSU u26.5-110

0.91u

Sorry Biev

IU +165

1.65u

OSU -4-110

1.1u

IU +4.5-110

0.25u

J.Smith o5.5 Recs-130

$1.00

J.Smith o73.5 Rec Yds-115

$1.00

OSU -3.5-112

THROWING ANOTHER UNIT DOWN. -3.5 ON DK I CAN’T RESIST

OSU -4-110

0.75u

Am I falling for it? They’re so much better.

J.Smith o5.5 Recs-125

0.8u

Jeremiah looks to step up in the big stage once again, this time, in his first Big 10 Championship. Smith this season has gone over this number in 7/11 games overall, averaging 6.5 per game. When he runs 20+ routes, he is over in 7/9 games, averaging 8.8 targets per game. He will now faces Indiana in the battle between the undefeateds, and #1 and #2 in the nation. Opposing WRs have been able to find success against this defense most of the season. Smith will be finding his spots all game long and I love this spot for him to rack up the grabs. Indiana’s run defense is very elite, ranking top 5 in the nation in success rate, stuff rate, and line yards on the season. Expecting the OSU offense to lean on Julian Sayin and the passing game a lot more than usual in this one. Indiana also runs a ton of zone coverage. Jeremiah feasts against zone and is OSU’s best WR by far against it, with a 0.32 TPRR against zone coverage on the year. Last season, in the postseason, we saw Smith have 7+ targets in 3/4 games. Love for this to continue for him tomorrow…

IU +4-110

0.91u

IU +4+100

IU +6-110

0.91u

@Stuckey2 @_Collin1 https://myaction.app/SXl6WrC0QYb

K.Black o32.5 Rush Yds-115

B.Inniss o14.5 Rec Yds-115

1.15u

R.Hemby o3.5 Rec Yds-115

IU +4-110

IU +4.5-110

0.91u

Join Discord: https://discord.gg/NcyhmJVXPe

IU +4-110

OSU -4-110

IU +145 (1H)

0.75u

F.Mendoza u22.5 Rush Yds-115

Under 24.5 (1H)-132

OSU o13.5 (1H)-110

1.1u

IU +6-110

$3.00

IU +6-110

Project Ohio State -4

Our +175 SGP For The Big Ten Championship
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Wilson's NCAAF Conference Championship Betting Card
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See more NCAAF Coverage

No props found

NCAAF Public Betting

Ohio State are 5-0 in their last 5 games.
Ohio State are 4-1 in their last 5 games against the spread
Ohio State are 4-1 in their road games against the spread
The totals have gone OVER in 2 of Ohio State' last 5 games
The totals have gone OVER in 4 of Ohio State' 7 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Ohio State	10-3	6-1	4-1	9-3	N/A
Indiana	8-5	4-3	3-2	5-5	2-0

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Ohio State	4-9	4-3	0-5	3-9	N/A
Indiana	8-5	5-2	3-2	7-3	0-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Ohio State	12-1	N/A	N/A	11-1	N/A
Indiana	13-0	N/A	N/A	10-0	2-0

date	opponent	score	spread	over/under	moneyline
Nov 29th	@MICH	W 27-9	-9.5 W	U 42.5	OSU -360
Nov 22nd	RUT	W 42-9	-28.5 W	U 54.5	OSU -9000
Nov 16th	UCLA	W 48-10	-33.5 W	O 46.5	OSU -9000
Nov 8th	@PUR	W 34-10	-29.5 L	U 50.5	OSU -7173
Nov 1st	PSU	W 38-14	-17.5 W	O 44.5	OSU -1200