Colorado vs. Houston Odds & Betting Predictions - September 12, 2025

Colorado at Houston

11:30 pm • ESPN

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Colorado Buffaloes

@

Houston Cougars

MatchupOpenSpreadTotalMoneyline
Colorado 1-1	+2.5	+5.5-115	o44.5-105	+180
Houston 2-0	u45.5	-5.5-105	u44.5-110	-218

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Friday 11:30 p.m.

September 12, 2025

TDECU StadiumHouston

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89°Fahrenheit

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0%Rain

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8Wind

COLO +6-112

1u

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NCAAF Public Betting

Houston are 2-0 in their last 5 games.
Houston are 2-0 in their last 5 games against the spread
Houston are 1-0 in their road games against the spread
The totals have gone OVER in 1 of Houston' last 2 games
The totals have gone OVER in 0 of Houston' 1 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Houston	2-0	1-0	1-0	2-0	N/A
Colorado	1-1	1-1	N/A	1-0	0-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Houston	1-1	0-1	1-0	1-1	N/A
Colorado	0-2	0-2	N/A	0-1	0-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Houston	2-0	N/A	N/A	2-0	N/A
Colorado	1-1	N/A	N/A	1-0	0-1

date	opponent	score	spread	over/under	moneyline
Sep 6th	@RICE	W 35-9	-13.5 W	O 38.5	HOU -600
Aug 29th	SFA	W 27-0	-23.5 W	U 54.5	HOU -2100
Dec 1st	@BYU	L 18-30	+12.5 W	O 40.5	BYU +380
Nov 24th	BAY	L 10-20	+7 L	U 51	BAY +217
Nov 16th	@ARI	L 3-27	+1 L	U 46.5	ARI -105

Total

Passing

426

YDS

340

39/60

Comps/Atts

31/49

7.1

YPA

6.94

3/0

TDs/INTs

4/0

6/36

Sacks/Yards

4/11

Rushing

277

Rush Yards

395

70

Attempts

84

3.96

YPC

4.7

3

TDs

3

Turnovers

Fumbles Lost

0

Interceptions

0

Efficiency

6/6 100%

Redzone

4/4 100%

12/29 0%

3rd Down

16/33 0%

2/2 0%

4th Down

0/2 0%

First Downs

40

Total

32

19

Pass

15

16

Rush

16

5

Penalty

1

Misc

/

Penalties/Yards

/

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MatchupOverUnder
Colorado 1-1	N/A	N/A
Houston 2-0	N/A	N/A