Kentucky vs. Iowa State Odds & Betting Predictions - March 22, 2026

Kentucky at Iowa State

6:45 pm • CBS
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Kentucky at Iowa State Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Kentucky
21-13
+4.5
+5.5-117
o145.5-111
+180
Iowa State
27-7
u146
-5.5-104
u145.5-110
-220
location pinSunday 6:45 p.m.
March 22, 2026
Enterprise CenterSt. Louis
Kentucky vs. Iowa State Expert Picks
Brian Bitler
Brian Bitler
Last 30d: 82-92-1 (-36.0u)
UK +5-105
3u
OldSchool0909
Last 30d: 55-51-1 (-0.5u)
UK +190
1u
UK +4.5-102
1u
Boomer Betz
Boomer Betz
Last 30d: 116-97-4 (+33.8u)
C.Chandler o9.5 Pts+170
$100.00
Brandon Kravitz
Brandon Kravitz
Last 30d: 69-89-0 (-10.8u)
UK +5.5-113
1.13u
JMann
JMann
Last 30d: 46-47-0 (+4.5u)
Under 145.5-110
1u
Babs .
Babs .
Last 30d: 107-84-0 (+11.3u)
UK +4.5-102
1u
Under 146.5-115
1u
Kendra Middleton
Kendra Middleton
Last 30d: 5-6-0 (-1.3u)
ISU -4.5-113
1u
Stuck 🚨
Stuck 🚨
Last 30d: 59-74-4 (-0.2u)
UK +5.5-115
0.45u
Some speculation here but don’t think Jefferson plays which would make this a very good number to have in pocket
Boomer Betz
Boomer Betz
Last 30d: 116-97-4 (+33.8u)
UK +5.5-115
$57.50
Half in for now

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Prop Odds Comparison

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Line Movement Tracker

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Kentucky vs. Iowa State Public Betting Percentages

Away Logo

Kentucky

Public

40%

Bets%

60%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Iowa State
20-1412-98-515-92-1
Kentucky
17-1710-127-57-86-6

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Iowa State
14-19-112-92-10-18-15-11-2
Kentucky
17-1711-116-67-85-7

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Iowa State
27-7N/AN/A19-51-2
Kentucky
21-13N/AN/A11-43-9

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Mar 20thTNSTW 108-74-25 WO 147.5ISU -10000
Mar 13th@ARIZL 80-82+3 WO 144.5ARIZ +142
Mar 12th@TTUW 75-53-7 WU 143.5ISU -298
Mar 11thASUW 91-42-13.5 WU 148.5ISU -1200
Mar 7thASUW 86-65-16.5 WO 148.5ISU -2100

Iowa State vs. Kentucky Injury Updates

Iowa State Injuries

  • Joshua Jefferson
    F

    Jefferson is questionable with ankle

    Questionable

  • Xzavion Mitchell
    F

    Mitchell is questionable with undisclosed

    Questionable

Kentucky Injuries

  • Jaland Lowe
    G

    Lowe is out for season with arm

    Out for Season

  • Jayden Quaintance
    F

    Quaintance is out with knee

    Out

Team Stats
28-60 (47%)
Field Goals
29-60 (48%)
16-22 (73%)
Free Throws
13-20 (65%)
8-23 (35%)
3P
9-23 (39%)
33.94
Rebounds
32.38
16
Assists
17.2
9.91
Turnovers
9.91
7.15
Steals
8.97
4.41
Blocks
2.71
18.44
Fouls
15.97

Kentucky vs. Iowa State Odds Comparison

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Kentucky at Iowa State Team Totals

MatchupOverUnder
Kentucky
21-13
N/A
N/A
Iowa State
27-7
N/A
N/A