Yankees vs. Red Sox Odds & Betting Predictions - April 22, 2026

Yankees at Red Sox

10:45 pm • MLB Network

New York Yankees

15-9

4 - 1

Boston Red Sox

9-15

pitcher		team	era	w-l
R.Suarez			4.00	1-2
M.Fried			2.40	3-1

MatchupOpenSpreadTotalMoneyline
Yankees 15-9	-1.5	-1.5+126	o7.5-105	-131
Red Sox 9-15	u7.5	+1.5-152	u7.5-115	+112

Wednesday 10:45 p.m.

April 22, 2026

Fenway ParkBoston

BOS +375 (Live)

NYY -125 (F5)

0.8u

R.Suarez u4.5 Ks+120

0.6u

Has topped out at 8.3 SwStr% in 4 starts - 3 of first 5 in NYY LU < 12.5 K% v LHP since LY - Hitter leaning umpire.

C.Wong To Record 2+ Total Bases Yes+176

0.13u

W.Contreras o0.5 HR+560

0.1u

BOS +125

Under 8-120

0.83u

Join Discord. All picks posted before 8am https://discord.gg/HjKxYKdSUy

R.Suarez u5.5 Ks-137

0.5u

NYY -1.5+135

0.27u

#EV Pinny +127 Circa +120 BM +122 BO +125

Under 8-118

M.Fried o17.5 Outs-155

R.Suarez o16.5 Outs-130

1.3u

NYY -140

0.5u

Bet to -150

BOS +125

0.4u

Yankees vs Red Sox: Struggling Boston Gives This Pick Value
Nick Martin•
Apr 22, 2026 UTC

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No props found

MLB Public Betting

Red Sox are 1-4 in their last 5 games.
Red Sox are 1-4 in their last 5 games against the spread
Red Sox are 4-8 in their road games against the spread
The totals have gone OVER in 2 of Red Sox' last 5 games
The totals have gone OVER in 4 of Red Sox' 12 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Red Sox	7-17	3-9	4-8	7-13	0-4
Yankees	13-11	6-7	7-4	11-11	2-0

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Red Sox	12-12	4-8	8-4	10-10	2-2
Yankees	9-13-2	6-6-1	3-7-1	8-12-2	1-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Red Sox	9-15	5-7	4-8	9-11	0-4
Yankees	15-9	8-5	7-4	13-9	2-0

date	opponent	score	spread	over/under	moneyline
Apr 21st	NYY	L 0-4	+1.5 L	U 8	NYY -121
Apr 20th	DET	W 8-6	-1.5 W	O 8.5	BOS -135
Apr 19th	DET	L 2-6	-1.5 L	O 7	DET -142
Apr 18th	DET	L 1-4	+1.5 L	U 6.5	DET +124
Apr 17th	DET	W 1-0	-1.5 L	U 8	BOS -128

Tanner Houck
SP
Houck is out with arm
Out
Triston Casas
1B
Casas is out with knee
Out
Patrick Sandoval
SP
Sandoval is out with elbow
Out
Kutter Crawford
SP
Crawford is out with wrist
Out
Romy Gonzalez
1B
Gonzalez is out with shoulder
Out

Carlos Rodon
SP
Rodon is out with elbow
Out
Gerrit Cole
SP
Cole is out with elbow
Out
Clarke Schmidt
SP
Schmidt is out with elbow
Out
Anthony Volpe
SS
Volpe is out with shoulder
Out

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PITCHER		PC	IP	K	ER
LM.Fried, P		100	8	9	0
LB.Headrick, P		26	1	0	1

HITTERS	H-AB	R	HR	RBI
1P.Goldschmidt, 1B	0-4	0	0	0
2A.Judge, RF	1-2	2	0	0
3C.Bellinger, CF	0-4	0	0	0
3C.Bellinger, LF	0-4	0	0	0
4G.Stanton, DH	2-4	1	0	0
5A.Rosario, 3B	1-1	1	1	4
5B.Rice, PH	0-1	0	0	0
5R.McMahon, 3B	0-1	0	0	0
6R.Grichuk, LF	1-2	0	0	0
6T.Grisham, PH	0-2	0	0	0
6T.Grisham, CF	0-2	0	0	0
7J.Chisholm, 2B	0-4	0	0	0
8J.Caballero, SS	1-3	0	0	0
9A.Wells, C	0-3	0	0	0

PITCHER	PC	IP	K	ER
LR.Suarez, P	71	4.2	4	4
RZ.Kelly, P	11	1	2	0
LE.Rivera, P	41	3.1	3	0

HITTERS	H-AB	R	RBI
1C.Rafaela, CF	0-4	0	0
2W.Contreras, 1B	0-3	0	0
3W.Abreu, RF	1-4	0	0
4T.Story, SS	1-4	1	0
5A.Monasterio, DH	0-3	0	0
6J.Duran, LF	3-4	0	1
7C.Durbin, 3B	0-4	0	0
8C.Wong, C	0-3	0	0
9I.Kiner-Falefa, 2B	0-3	0	0