Yankees vs. Red Sox Odds & Betting Predictions - April 21, 2026

Yankees at Red Sox

10:45 pm • YES
4 - 0
Starting Pitchers
pitcherteameraw-l
Connelly Early logoC.EarlyBoston Red Sox logo2.881-1
Luis Gil logoL.GilNew York Yankees logo4.111-1

Yankees at Red Sox Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Yankees
15-9
-1.5
-1.5+165
o8-115
+102
Red Sox
9-15
u8.5
+1.5-173
u8-105
-121
location pinTuesday 10:45 p.m.
April 21, 2026
Fenway ParkBoston
Yankees vs. Red Sox Expert Picks
YBK Picks.com
Last 30d: 27-31-3 (-13.3u)
BOS -120
2u
BOS -110
1u
Join Discord. All picks posted before 8am https://discord.gg/HjKxYKdSUy
Scott Rickenbach
Scott Rickenbach
Last 30d: 90-119-4 (-35.9u)
Over 8.5-105
1u
Over 8.5-105
1u
Ryan Minion
Ryan Minion
Last 30d: 243-308-4 (-11.0u)
Under 4.5 (F5)-110
$1.00
Frank Ammirante
Frank Ammirante
Last 30d: 267-310-14 (-4.6u)
C.Early u4.5 Hits Allowed-146
1.46u
Under 4.5 (F5)-115
1u
Sean Zerillo
Sean Zerillo
Last 30d: 161-157-12 (-7.6u)
NYY -108
0.5u
Bet to -115
Frank Ammirante
Frank Ammirante
Last 30d: 267-310-14 (-4.6u)
Under 8.5-115
1u
Matt Trollo
Matt Trollo
Last 30d: 50-53-7 (-3.5u)
BOS -110 (F5)
0.55u
(B365) Gil steep decline, but.this price is about my limit.
Doug Ziefel
Doug Ziefel
Last 30d: 283-377-23 (-23.1u)
Under 8.5-105
0.5u
BOS -110
0.55u

Yankees vs. Red Sox Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Yankees vs. Red Sox Public Betting Percentages

Away Logo

Yankees

Public

61%

Bets%

39%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Red Sox
7-173-94-87-130-4
Yankees
13-116-77-411-112-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Red Sox
12-124-88-410-102-2
Yankees
9-13-26-6-13-7-18-12-21-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Red Sox
9-155-74-89-110-4
Yankees
15-98-57-413-92-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 20thDETW 8-6-1.5 WO 8.5BOS -135
Apr 19thDETL 2-6-1.5 LO 7DET -142
Apr 18thDETL 1-4+1.5 LU 6.5DET +124
Apr 17thDETW 1-0-1.5 LU 8BOS -128
Apr 15th@MINW 9-5-1.5 WO 8.5BOS -135

Red Sox vs. Yankees Injury Updates

Red Sox Injuries

  • Tanner Houck
    SP

    Houck is out with arm

    Out

  • Triston Casas
    1B

    Casas is out with knee

    Out

  • Patrick Sandoval
    SP

    Sandoval is out with elbow

    Out

  • Kutter Crawford
    SP

    Crawford is out with wrist

    Out

  • Romy Gonzalez
    1B

    Gonzalez is out with shoulder

    Out

Yankees Injuries

  • Carlos Rodon
    SP

    Rodon is out with elbow

    Out

  • Gerrit Cole
    SP

    Cole is out with elbow

    Out

  • Clarke Schmidt
    SP

    Schmidt is out with elbow

    Out

  • Anthony Volpe
    SS

    Volpe is out with shoulder

    Out

Yankees vs. Red Sox Box Score
Yankees Player Stats
Projected
PITCHERPCIPKER
Luis Gil logoRL.Gil, P836.120
Brent Headrick logoLB.Headrick, P130.210
Tim Hill logoLT.Hill, P10100
David Bednar logoRD.Bednar, P19110
HITTERSH-ABRHRRBI
Amed Rosario logo1A.Rosario, 3B0-3100
Ryan McMahon logo1R.McMahon, 3B0-1000
Aaron Judge logo2A.Judge, RF1-3100
Ben Rice logo3B.Rice, 1B0-4000
Giancarlo Stanton logo4G.Stanton, DH2-4113
Cody Bellinger logo5C.Bellinger, CF1-3100
Cody Bellinger logo5C.Bellinger, LF1-3100
Randal Grichuk logo6R.Grichuk, LF2-4001
Trent Grisham logo6T.Grisham, CF0-0000
Jazz Chisholm logo7J.Chisholm, 2B2-4000
Jose Caballero logo8J.Caballero, SS1-4000
Austin Wells logo9A.Wells, C1-4000
Red Sox Player Stats
Projected
PITCHERPCIPKER
Connelly Early logoLC.Early, P925.143
Jack Anderson logoRJ.Anderson, P31221
Tyler Samaniego logoLT.Samaniego, P201.230
HITTERSH-ABRHRRBI
Roman Anthony logo1R.Anthony, LF0-3000
Willson Contreras logo2W.Contreras, 1B1-4000
Masataka Yoshida logo3M.Yoshida, DH0-4000
Wilyer Abreu logo4W.Abreu, RF0-4000
Trevor Story logo5T.Story, SS0-3000
Ceddanne Rafaela logo6C.Rafaela, CF1-3000
Marcelo Mayer logo7M.Mayer, 2B1-1000
Andruw Monasterio logo7A.Monasterio, PH0-1000
Andruw Monasterio logo7A.Monasterio, 2B0-1000
Jarren Duran logo7J.Duran, PH0-1000
Caleb Durbin logo8C.Durbin, 3B0-3000
Carlos Narvaez logo9C.Narvaez, C1-3000

Yankees vs. Red Sox Odds Comparison

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Yankees at Red Sox Team Totals

MatchupOverUnder
Yankees
15-9
N/A
N/A
Red Sox
9-15
N/A
N/A