Red Sox vs. Yankees Odds & Betting Predictions - August 21, 2025

Red Sox at Yankees

11:15 pm • FOX

Boston Red Sox

1-2

6 - 3

New York Yankees

3-4

pitcher		team	era	w-l
L.Gil			3.32	4-1
L.Giolito			3.41	10-4

MatchupOpenSpreadTotalMoneyline
Red Sox 1-2	+1.5	+1.5-173	o8.5-121	+122
Yankees 3-4	u8.5	-1.5+140	u8.5-103	-144

Thursday 11:15 p.m.

August 21, 2025

Yankee StadiumBronx

NYY +270 (Live)

Worth a small position at these odds that include last at bats

Under 8.5-105

BOS +122

1.22u

L.Gil u15.5 Outs-125

0.8u

BOS +1.5-167

0.6u

BOS +130

1.3u

BOS +130

1.3u

NYY -145

📊 27-7 W/L (79.41%) ROI ~ 32.87% L10 ~ 7-3 📈 Home Favorite On Win Streak in Series Opener ✅ Team is on 2+ game winning streak ✅ Team is playing against division opponent ✅ Team is favored to win ✅ Team is at home ✅ Game number 1 of series

R.Anthony o1.5 Hits + Runs + RBIs-105

0.95u

J.Chisholm o1.5 Hits + Runs + RBIs+110

1.1u

NYY -140 (F5)

0.36u

BOS +128

BOS +0.5 (F5)-120

1.2u

NYY -148

NYY -135

0.68u

Bet to -143

Red Sox vs Yankees: +144 SGP for Thursday Opener
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Aug 21, 2025 UTC
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No props found

MLB Public Betting

Yankees are 5-0 in their last 5 games.
Yankees are 4-1 in their last 5 games against the spread
Yankees are 35-46 in their road games against the spread
The totals have gone OVER in 2 of Yankees' last 5 games
The totals have gone OVER in 36 of Yankees' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Yankees	78-84	43-38	35-46	68-72	9-12
Red Sox	87-75	43-38	44-37	53-50	34-23

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Yankees	76-81-5	36-44-1	40-37-4	64-73-3	11-8-2
Red Sox	76-82-4	33-45-3	43-37-1	50-50-3	26-30-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Yankees	94-68	50-31	44-37	85-55	8-13
Red Sox	89-73	48-33	41-40	61-42	28-29

date	opponent	score	spread	over/under	moneyline
Aug 20th	@TB	W 6-4	-1.5 W	O 8.5	NYY -106
Aug 19th	@TB	W 13-3	-1.5 W	O 8	NYY -135
Aug 17th	@STL	W 8-4	-1.5 W	O 9	NYY -158
Aug 16th	@STL	W 12-8	-1.5 W	O 7.5	NYY -142
Aug 16th	@STL	W 4-3	-1.5 L	U 9	NYY -146

Tanner Houck
SP
Houck is out with arm
Out
Patrick Sandoval
SP
Sandoval is out with elbow
Out
Kutter Crawford
SP
Crawford is out with knee
Out
Jovani Moran
RP
Moran is out with arm
Out

Gerrit Cole
SP
Cole is out for season with elbow
Out for Season

See more MLB Injuries

PITCHER	PC	IP	K	ER
RL.Giolito, P	97	4.2	4	3
LJ.Wilson, P	21	0.1	1	0
RG.Weissert, P	23	1.1	0	0
LS.Matz, P	13	0.2	1	0
RG.Whitlock, P	7	1	0	0
LA.Chapman, P	14	1	0	0

HITTERS	H-AB	R	HR	RBI
1R.Anthony, RF	2-5	2	1	3
2A.Bregman, 3B	3-5	0	0	0
3J.Duran, LF	1-5	0	0	0
4T.Story, SS	1-3	1	0	0
5N.Lowe, 1B	1-4	0	0	2
6M.Yoshida, DH	1-4	0	0	0
6R.Gonzalez, PH	0-1	0	0	0
6R.Gonzalez, DH	0-1	0	0	0
7C.Rafaela, CF	0-4	1	0	0
8D.Hamilton, 2B	1-3	2	0	0
9C.Narvaez, C	0-3	0	0	0

PITCHER	PC	IP	K	ER
RL.Gil, P	93	5	3	1
RC.Doval, P	13	0.1	0	1
RM.Leiter, P	6	0.2	0	0
RL.Weaver, P	32	0.2	1	1
LT.Hill, P	18	1	1	0
RY.De Los Santos, P	16	1.1	0	0

HITTERS	H-AB	R	HR	RBI
1T.Grisham, CF	0-5	0	0	0
2A.Judge, DH	1-4	1	0	0
3C.Bellinger, LF	1-4	0	0	0
4G.Stanton, RF	0-4	0	0	0
5B.Rice, C	2-3	1	1	1
6J.Chisholm, 2B	2-4	1	0	1
7P.Goldschmidt, 1B	2-3	0	0	1
8R.McMahon, 3B	0-4	0	0	0
9A.Volpe, SS	0-4	0	0	0