Fighting Irish vs. Panthers Odds & Betting Predictions - November 15, 2025
Fighting Irish at Panthers
5:00 pm • ABCFighting Irish at Panthers Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Fighting Irish 10-2 | -10 | -13.5-107 | o55.5-110 | -477 |
Panthers 8-5 | u56.5 | +13.5-112 | u55.5-110 | +372 |

Acrisure StadiumPittsburgh
Fighting Irish vs. Panthers Expert Picks
Mike Calabrese
Last 30d: 52-52-2 (+13.9u)
ND -21.5 (Live)-102
1u
Sandy Plashkes
Last 30d: 87-77-7 (-0.5u)
W.Pauling o43.5 Rec Yds-114
1.71u
@wwiseguys told me this is a winner
Bet Labs
Last 30d: 15-12-0 (+1.8u)
ND -12.5-107
1u
Allan Lem
Last 30d: 113-95-3 (+4.3u)
ND -12.5-112
0.5u
Mjaybrod
Last 30d: 62-42-0 (+22.2u)
PITT u20.5-106
0.94u
Have fun scoring 10 points
John Feltman
Last 30d: 73-62-4 (-1.1u)
PITT +14-120
4.8u
Mike McNamara
Last 30d: 82-82-0 (+3.8u)
ND -13-110
0.36u
Vegas Refund
Last 30d: 60-48-0 (+7.5u)
ND -12.5-110
1u
Sandy Plashkes
Last 30d: 87-77-7 (-0.5u)
ND -12.5-110
1u
💰🦡 Jake
Last 30d: 107-103-2 (+37.1u)
PITT +300 (1H)
0.35u
PITT +7.5 (1H)-125
1.25u
Big Bets On Campus (CFB)
Last 30d: 0-0-0 (+0.0u)
C.Carr o254.5 Pass Yds-115
1u
@_Collin1 https://myaction.app/XOqm3YriiYb
Ryan Minion
Last 30d: 186-211-3 (+42.1u)
ND -12.5-110
$1.00
Cam Is Money
Last 30d: 57-61-1 (-9.1u)
ND -10.5-115
0.87u
Anders
Last 30d: 10-10-0 (-0.4u)
ND -10.5-115
1u
Pretty simple, 1 team cares, 1 team doesn’t. Wish i got the 10 but pretty confident wee see one way action on ND the rest of the way, would likely add more if 10 came back. Good to 12.5 for full risk
Duck
Last 30d: 96-93-0 (-1.9u)
ND -26.5+390
0.25u
Margin Call
ND -19.5+200
0.5u
Margin Call
ND -10.5-115
1u
Doug Ziefel
Last 30d: 148-173-1 (-11.4u)
Under 55.5-110
0.5u
Collin Wilson
Last 30d: 0-0-0 (+0.0u)
PITT +10.5-105
1.05u
Project Notre Dame -6; Pitt defense 2nd nationally defensive rush success rate, 57% efficiency and no explosives against outside zone (Notre Dame primary concept)
Fighting Irish vs. Panthers Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Fighting Irish vs. Panthers Public Betting Percentages
Betting Trends
- Panthers are 3-2 in their last 5 games.
- Panthers are 3-2 in their last 5 games against the spread
- Panthers are 4-1 in their road games against the spread
- The totals have gone OVER in 2 of Panthers' last 5 games
- The totals have gone OVER in 5 of Panthers' 7 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 8-4 | 4-3 | 4-1 | 5-1 | 2-3 | |
| 6-6 | 4-3 | 2-3 | 5-6 | N/A |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 8-4 | 5-2 | 3-2 | 4-2 | 3-2 | |
| 7-5 | 4-3 | 3-2 | 6-5 | N/A |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 8-4 | N/A | N/A | 5-1 | 2-3 | |
| 10-2 | N/A | N/A | 9-2 | N/A |
Last 5 Matchups
Team Stats
212
YDS
149
21/32
Comps/Atts
19/39
6.625
YPA
3.8205128205128207
2/2
TDs/INTs
1/1
1/8
Sacks/Yards
4/33
8/84
Penalties/Yards
5/41
Fighting Irish vs. Panthers Odds Comparison
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Fighting Irish at Panthers Team Totals
MatchupOverUnder | ||
|---|---|---|
Fighting Irish 10-2 | N/A | N/A |
Panthers 8-5 | N/A | N/A |






