LSU vs. Ole Miss Odds & Betting Predictions - September 27, 2025

LSU at Ole Miss

4:00 pm • ESPN Networks

MatchupOpenSpreadTotalMoneyline
LSU 0-0	-1.5	-1.5-122	N/A	-128
Ole Miss 0-0	+1.5+100	N/A	+106

Saturday 4:00 p.m.

September 27, 2025

Vaught-Hemingway StadiumOxford

LSU -113

1.13u

From BBOC SEC Preview; LSU Nussmeier and elite stable of WRs to take on a depleted Ole Miss secondary. Tigers get SELA W4 while Ole Miss faces Tulane

No props found

	overall	home	away	favorite	underdog
Ole Miss	N/A	N/A	N/A	N/A	N/A
LSU	N/A	N/A	N/A	N/A	N/A

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Ole Miss	N/A	N/A	N/A	N/A	N/A
LSU	N/A	N/A	N/A	N/A	N/A

	overall	home	away	favorite	underdog
Ole Miss	N/A	N/A	N/A	N/A	N/A
LSU	N/A	N/A	N/A	N/A	N/A

date	opponent	score	spread	over/under	moneyline
Jan 3rd	DUKE	W 52-20	-18.5 W	O 51.5	MISS -1000
Nov 29th	MSST	W 26-14	-26 L	U 63.5	MISS -3600
Nov 23rd	@FLA	L 17-24	-13.5 L	U 57.5	FLA -500
Nov 9th	UGA	W 28-10	+2.5 W	U 54.5	MISS +114
Nov 2nd	@ARK	W 63-31	-8 W	O 54	MISS -305

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MatchupOverUnder
LSU 0-0	N/A	N/A
Ole Miss 0-0	N/A	N/A