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Padres vs. Blue Jays Odds & Betting Predictions - May 22, 2025

Padres at Blue Jays

5:07 pm • SDPA

San Diego Padres

56-49
6
6 - 7

Toronto Blue Jays

63-42
7
Starting Pitchers
pitcherteameraw-l
Bowden Francis logoB.FrancisToronto Blue Jays logo6.052-8
Stephen Kolek logoS.KolekSan Diego Padres logo4.283-5

Padres at Blue Jays Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Padres
56-49
-1.5
-1.5+145
o8.5-122
-118
Blue Jays
63-42
u9
+1.5-170
u8.5+100
-102
location pinThursday 5:07 p.m.
May 22, 2025
Rogers CentreToronto
Padres vs. Blue Jays Expert Picks
Cam Is Money
Cam Is Money
Last 30d: 124-123-1 (+16.3u)
TOR +105 (Live)
1.05u
Gamblers Dream
Gamblers Dream
Last 30d: 1-1-0 (-0.5u)
TOR +124 (Live)
1.24u
Sir Lockselot
Sir Lockselot
Last 30d: 33-53-0 (-7.3u)
SD -1.5+150
2u
🔑 Padres -1.5 +150 (FanDuel) 2u These fellas are so due and the better team here. Kolek is legit, love this spot Bowden is very bad too
Capper Central
Capper Central
Last 30d: 107-87-0 (+4.3u)
TOR +100
1u
Picks Office
Picks Office
Last 30d: 76-72-0 (+7.6u)
SD -115
1u
Padres' offense in a deep freeze – 0-for-32 w/ RISP, just 3 runs last 5 games. But .259 AVG on the season (6th MLB), 4.33 runs/game. Regression coming. Luis Arraez hot – 8-game hit streak, .380 career AVG vs TOR. Slump-breaking matchup vs shaky Bowden Francis looming. Francis struggles big time – 2-6 record, 5.63 ERA. 15 ER over last 3 home starts. Jays just 2-6 in last 8 home starts w/ him on mound. Padres starter Kolek? 2.33 ERA, 19.1 IP. Pads 52-24 last 76 as favs. Today’s desperation spot, morale high, bounce-back brewing. San Diego pen shaky lately (8.02 ERA last 3), but strong overall – 3.69 ERA, 1.15 WHIP across 148.2 IP. Kolek goes 5+, bullpen closes door. Padres hungry to avoid sweep, end 5-game skid. Too much talent to keep quiet.
Austin Pendergrass
Austin Pendergrass
Last 30d: 37-62-0 (-16.9u)
SD -124 (F5)
0.5u
Boomer Betz
Boomer Betz
Last 30d: 234-234-4 (+15.3u)
SD -116
1u
Brian Bitler
Brian Bitler
Last 30d: 59-69-2 (-17.8u)
TOR +105
3.15u
Lines at Lunch
Lines at Lunch
Last 30d: 36-48-5 (-17.5u)
SD -112
1.12u
Cam Is Money
Cam Is Money
Last 30d: 124-123-1 (+16.3u)
D.Varsho o1.5 Total Bases+127
1.27u
Sean Zerillo
Sean Zerillo
Last 30d: 154-156-11 (+9.6u)
TOR +105
0.53u
Bet to -102
Cam Is Money
Cam Is Money
Last 30d: 124-123-1 (+16.3u)
Over 5 (F5)-115
1u
Sandy Plashkes
Sandy Plashkes
Last 30d: 78-66-2 (+19.9u)
SD -112
1.68u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 168-176-3 (-36.2u)
SD -108
1.08u
Previous dogs off shutout now fav Overall: 159-75-0,68% (ROI:20%) Season:2-2-0,50% (ROI:-10%)

Padres vs. Blue Jays Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Padres vs. Blue Jays Public Betting Percentages

Away Logo

Padres

Public

Home Logo

Blue Jays

66%

Bets%

34%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Blue Jays are 4-1 in their last 5 games.
  • Blue Jays are 5-0 in their last 5 games against the spread
  • Blue Jays are 29-22 in their road games against the spread
  • The totals have gone OVER in 2 of Blue Jays' last 5 games
  • The totals have gone OVER in 31 of Blue Jays' 54 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Blue Jays		64-4135-1929-2223-2340-17
Padres		56-4927-2229-2724-3031-19

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Blue Jays		54-47-431-21-223-26-224-21-129-25-3
Padres		41-60-419-29-122-31-326-26-215-33-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Blue Jays		63-4237-1726-2528-1834-23
Padres		56-4931-1825-3131-2324-26

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 21stSDW 14-0-1.5 WO 9TOR -165
May 20thSDW 3-0+1.5 WU 7.5TOR -106
May 18thDETL 2-3-1.5 LU 8.5DET -125
May 17thDETW 2-1+1.5 WU 8.5TOR +114
May 16thDETL 4-5+1.5 WO 8.5DET -102

Blue Jays vs. Padres Injury Updates

Blue Jays Injuries

  • Anthony Santander
    RF

    Santander is out with shoulder

    Out

  • Alek Manoah
    SP

    Manoah is out with elbow

    Out

  • Bowden Francis
    SP

    Francis is out with shoulder

    Out

Padres Injuries

  • Joe Musgrove
    SP

    Musgrove is out for season with elbow

    Out for Season

  • Michael King
    SP

    Michael King (shoulder) has been scratched Saturday. Sean Reynolds will start for the Padres.

    Out

See more MLB Injuries Right Arrow
Padres vs. Blue Jays Box Score
Padres Player Stats
Projected
PITCHERPCIPKER
Stephen Kolek logoRS.Kolek, P92663
Yuki Matsui logoLY.Matsui, P22100
Sean Reynolds logoRS.Reynolds, P16100
Jason Adam logoRJ.Adam, P24100
Robert Suarez logoRR.Suarez, P16110
Jeremiah Estrada logoRJ.Estrada, P110.101
HITTERSH-ABRHRRBI
Fernando Tatis logo1F.Tatis, RF0-4000
Luis Arraez logo2L.Arraez, DH2-5001
Manny Machado logo3M.Machado, 3B0-5100
Jackson Merrill logo4J.Merrill, CF2-4200
Gavin Sheets logo5G.Sheets, 1B3-5225
Jake Cronenworth logo6J.Cronenworth, 2B0-3000
Elias Diaz logo7E.Diaz, C0-5000
Jose Iglesias logo8J.Iglesias, SS1-4100
Brandon Lockridge logo9B.Lockridge, LF0-2000
Jason Heyward logo9J.Heyward, PH0-1000
Jason Heyward logo9J.Heyward, LF0-1000
Xander Bogaerts logo9X.Bogaerts, PH0-1000
Tyler Wade logo9T.Wade, LF0-0000
Blue Jays Player Stats
Projected
PITCHERPCIPKER
Bowden Francis logoRB.Francis, P77442
Yariel Rodriguez logoRY.Rodriguez, P241.130
Mason Fluharty logoLM.Fluharty, P12110
Chad Green logoRC.Green, P120.200
Yimi Garcia logoRY.Garcia, P9100
Jeff Hoffman logoRJ.Hoffman, P23122
Brendon Little logoLB.Little, P341.210
Braydon Fisher logoRB.Fisher, P30.100
HITTERSH-ABRHRRBI
Bo Bichette logo1B.Bichette, SS2-6101
Vladimir Guerrero logo2V.Guerrero, 1B0-5100
Daulton Varsho logo3D.Varsho, DH1-5102
Addison Barger logo4A.Barger, 3B3-4001
Ernie Clement logo5E.Clement, 2B0-5000
Nathan Lukes logo6N.Lukes, RF1-4101
Nathan Lukes logo6N.Lukes, CF1-4101
Jonatan Clase logo7J.Clase, LF2-3101
Myles Straw logo8M.Straw, CF0-4000
George Springer logo8G.Springer, PH0-1000
George Springer logo8G.Springer, RF0-1000
Tyler Heineman logo9T.Heineman, C2-4200
Alejandro Kirk logo9A.Kirk, PH1-1000
Alejandro Kirk logo9A.Kirk, C1-1000

Padres vs. Blue Jays Odds Comparison

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Padres at Blue Jays Team Totals

MatchupOverUnder
Padres
56-49
o4.5-104
u4.5-125
Blue Jays
63-42
o4.5+117
u4.5-149