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Purdue vs. Notre Dame Odds & Betting Predictions - September 20, 2025

Purdue at Notre Dame

7:30 pm • NBC

Purdue Boilermakers

2-10
30
30 - 56

Notre Dame Fighting Irish

10-2
56

Purdue at Notre Dame Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Purdue
2-10
+30.5
+24.5-106
o51-110
+1280
Notre Dame
10-2
u48.5
-24.5-115
u51-110
-4000
location pinSaturday 7:30 p.m.
September 20, 2025
Notre Dame StadiumSouth Bend
Purdue vs. Notre Dame Expert Picks
The Degenerates
The Degenerates
Last 30d: 99-89-5 (+3.8u)
PUR +25.5-105
1.05u
Brian Bitler
Brian Bitler
Last 30d: 92-77-1 (+27.7u)
PUR +24.5-105
3u
💰🦡 Jake
💰🦡 Jake
Last 30d: 93-112-2 (-12.7u)
Over 51.5-105
1.5u
Dan Gaspar
Dan Gaspar
Last 30d: 53-45-4 (+2.1u)
A.Branch u31.5 Rec Yds-114
1u
Babs .
Babs .
Last 30d: 129-93-0 (+22.3u)
Over 52.5-120
0.83u
Boomer Betz
Boomer Betz
Last 30d: 133-151-4 (-19.1u)
ND -26.5+100
1u

Purdue vs. Notre Dame Previews & Analysis

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    Purdue vs. Notre Dame: The Team Total to Bet

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    Sep 20, 2025 UTC
  • Your Week 4 NCAAF Betting Cheat Sheet article feature image

    Your Week 4 NCAAF Betting Cheat Sheet

    Pete Ruden•
    Sep 20, 2025 UTC
  • College Football Week 4 Best Bets & Player Props! | Big Bets On Campus LIVE! article feature image

    College Football Week 4 Best Bets & Player Props! | Big Bets On Campus LIVE!

    •
    Sep 19, 2025 UTC
  • Auburn vs Oklahoma BEST BETS! | College Football Best Bets & Preview | BBOC article feature image

    Auburn vs Oklahoma BEST BETS! | College Football Best Bets & Preview | BBOC

    Stuckey•
    Sep 19, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Purdue vs. Notre Dame Public Betting Percentages

Away Logo

Purdue

Public

Home Logo

Notre Dame

57%

Bets%

43%

Money%

NCAAF Public Betting Right Arrow

Betting Trends

  • Notre Dame are 4-1 in their last 5 games.
  • Notre Dame are 3-2 in their last 5 games against the spread
  • Notre Dame are 2-3 in their road games against the spread
  • The totals have gone OVER in 5 of Notre Dame' last 5 games
  • The totals have gone OVER in 4 of Notre Dame' 7 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Notre Dame		6-64-32-35-6N/A
Purdue		4-7-13-41-3-11-23-5-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Notre Dame		7-54-33-26-5N/A
Purdue		4-82-52-30-34-5

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Notre Dame		10-2N/AN/A9-2N/A
Purdue		2-10N/AN/A2-10-9

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 13thTA&ML 40-41-6.5 LO 49.5TA&M -250
Aug 31st@MIAL 24-27-3 LO 50.5MIA -148
Jan 21stOSUL 23-34+8.5 LO 45.5OSU +295
Jan 10th@PSUW 27-24+1.5 WO 45.5ND -102
Jan 2nd@UGAW 23-10-1.5 WU 45.5ND -110
Team Stats

Total

379
Total Yards
535
68
Total Plays
63
5.573529411764706
Yards Per Play
8.492063492063492

Passing

303
YDS
281
25/40
Comps/Atts
17/20
7.575
YPA
14.05
3/2
TDs/INTs
2/0
2/13
Sacks/Yards
1/6

Rushing

76
Rush Yards
254
28
Attempts
43
2.7142857142857144
YPC
5.906976744186046
0
TDs
5

Turnovers

0
Fumbles Lost
1
2
Interceptions
0

Efficiency

3/3 100%
Redzone
3/4 75%
4/14 0%
3rd Down
6/10 0%
1/1 0%
4th Down
0/2 0%

First Downs

20
Total
27
15
Pass
12
4
Rush
13
1
Penalty
2

Misc

7/75
Penalties/Yards
3/30

Purdue vs. Notre Dame Odds Comparison

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Purdue at Notre Dame Team Totals

MatchupOverUnder
Purdue
2-10
o13-112
u13-112
Notre Dame
10-2
o37.5-125
u37.5-106