Ole Miss vs. Oklahoma Odds & Betting Predictions - October 25, 2025
Ole Miss at Oklahoma
4:00 pm • ABCOle Miss at Oklahoma Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Ole Miss 12-1 | +2.5 | +4.5-115 | o52.5-105 | +160 |
 Oklahoma 10-3 | u50.5 | -4.5-115 | u52.5-110 | -200 |
Gaylord Family Oklahoma Memorial StadiumNorman
Ole Miss vs. Oklahoma Expert Picks
Duck
Last 30d: 110-98-1 (+0.8u)
OU +1.5 (Live)-105
0.37u
OU +0.5 (Live)+267
0.37u
The Propfessor
Last 30d: 51-40-2 (+5.8u)
T.Blaylock o55.5 Rush Yds-115
1u
Mjaybrod
Last 30d: 78-61-1 (+18.3u)
OU -5-110
1u
Sandy Plashkes
Last 30d: 104-120-0 (-33.1u)
OU -5-110
1.1u
Didn’t mean to add this
Vegas Refund
Last 30d: 33-33-0 (-3.4u)
OU -4.5-110
1.1u
Capper Central
Last 30d: 40-38-1 (+1.8u)
OU -4.5-110
1.1u
Top Shelf Action 🥃
Last 30d: 73-77-1 (+3.0u)
OU -2.5 (1H)-112
0.9u
Picks Office
Last 30d: 172-136-1 (+21.2u)
Under 54.5-125
1u
X: PicksOffice
Boomer Betz
Last 30d: 101-110-1 (-17.7u)
Over 52.5-107
0.93u
Big Bets On Campus (CFB)
Last 30d: 56-57-1 (-3.0u)
OU -5.5-108
1u
@Stuckey2 Favorite Favorite https://myaction.app/SwerLY0kJXb
Mike Calabrese
Last 30d: 33-27-0 (+19.4u)
MISS +5.5-110
1u
Two factors pushed me to the points: Is this the same Mateer pre injury? He’s not using his legs nearly as much and he’s checking it down a ton. And the second piece, how much of OU’s defense profile is based on the teams/QBs they’ve faced? Michigan? Auburn? Texas? Those are their best opponents, and all three have failed to live up to preseason hype. Gimme the points with Chambliss and the Lane 🚂
Duck
Last 30d: 110-98-1 (+0.8u)
MISS u24.5 Team Total-130
0.6u
Bet MGM.
Ole Miss vs. Oklahoma Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Ole Miss vs. Oklahoma Public Betting Percentages
Betting Trends
- Oklahoma are 4-1 in their last 5 games.
- Oklahoma are 4-1 in their last 5 games against the spread
- Oklahoma are 4-0 in their road games against the spread
- The totals have gone OVER in 1 of Oklahoma' last 5 games
- The totals have gone OVER in 1 of Oklahoma' 7 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
431
Total Yards
359
87
Total Plays
60
4.954022988505747
Yards Per Play
5.983333333333333
315
YDS
223
24/46
Comps/Atts
17/32
6.8478260869565215
YPA
6.96875
1/0
TDs/INTs
1/0
1/5
Sacks/Yards
3/10
Ole Miss vs. Oklahoma Odds Comparison
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Ole Miss at Oklahoma Team Totals
MatchupOverUnder | ||
|---|---|---|
Ole Miss 12-1 | o23.5-114 | u23.5-112 |
Oklahoma 10-3 | o28.5-110 | u28.5-120 |