Kentucky vs. Louisville Odds & Betting Predictions - November 29, 2025

Kentucky at Louisville

5:00 pm • ACC Network

Kentucky Wildcats

@

Louisville Cardinals

MatchupOpenSpreadTotalMoneyline
Kentucky 5-6	+6.5	+3-110	o46.5-115	+127
Louisville 7-4	u47.5	-3-110	u46.5-105	-152

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Saturday 5:00 p.m.

November 29, 2025

L&N Federal Credit Union StadiumLouisville

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40°Fahrenheit

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0%Rain

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7Wind

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NCAAF Public Betting

Louisville are 3-2 in their last 5 games.
Louisville are 1-4 in their last 5 games against the spread
Louisville are 3-1 in their road games against the spread
The totals have gone OVER in 2 of Louisville' last 5 games
The totals have gone OVER in 4 of Louisville' 7 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Louisville	3-8	0-7	3-1	2-7	1-1
Kentucky	5-6	4-3	1-3	1-2	4-4

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Louisville	5-6	4-3	1-3	5-4	0-2
Kentucky	7-3-1	4-2-1	3-1	1-1-1	6-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Louisville	7-4	N/A	N/A	6-3	1-1
Kentucky	5-6	N/A	N/A	3-0	2-6

date	opponent	score	spread	over/under	moneyline
Nov 22nd	@SMU	L 6-38	+3.5 L	U 49.5	SMU +154
Nov 15th	CLEM	L 19-20	-1.5 L	U 51	CLEM -125
Nov 9th	CAL	L 26-29	-18.5 L	O 48.5	CAL -1100
Nov 1st	@VT	W 28-16	-10.5 W	U 52.5	LOU -395
Oct 25th	BC	W 38-24	-25.5 L	O 54.5	LOU -2800

Total

Passing

2323

YDS

2533

216/342

Comps/Atts

240/373

6.79

YPA

6.79

15/12

TDs/INTs

13/9

23/138

Sacks/Yards

22/159

Rushing

1630

Rush Yards

1693

406

Attempts

335

4.01

YPC

5.05

19

TDs

21

Turnovers

Fumbles Lost

12

Interceptions

9

Efficiency

28/36 77.8%

Redzone

29/32 90.6%

62/145 0%

3rd Down

54/146 0%

11/20 0%

4th Down

4/9 0%

First Downs

227

Total

209

113

Pass

109

94

Rush

82

20

Penalty

18

Misc

/

Penalties/Yards

/

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MatchupOverUnder
Kentucky 5-6	N/A	N/A
Louisville 7-4	N/A	N/A