Iowa State vs. Cincinnati Odds & Betting Predictions - October 4, 2025
Iowa State at Cincinnati
4:00 pm • ESPN2Iowa State at Cincinnati Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Iowa State 5-0 | -3.5 | +1.5-108 | o56.5-110 | +102 |
 Cincinnati 3-1 | u54.5 | -1.5-112 | u56.5-105 | -120 |
Nippert StadiumCincinnati
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Iowa State vs. Cincinnati Expert Picks
Duck
Last 30d: 76-61-0 (+8.0u)
Over 54.5-115
1.15u
Iowa state banged up in the secondary and very concerned about Cincinnati and their pass defense which gave up 440 pass yards last week on just 19 completions. Feel this one has a likelihood to be played in the 30s by both teams rather than the 20s. Should get over this total.
Babs .
Last 30d: 76-70-1 (+6.3u)
CIN -120
1u
Collin Wilson
Last 30d: 83-56-3 (+14.1u)
CIN o27.5 Team Total-116
1.16u
Project Cincinnati 28.5 points; Iowa State sever issues against inside and outside zone read, 41% success rate or worse depending on personnel. Sorsby destroys Quarters coverage and has already seen two Power Four nickel packages this season. Cincy currently 19th quality drives, 6th offensive finishing drives
Cam Is Money
Last 30d: 57-70-3 (-12.4u)
CIN -125
1u
Mike Calabrese
Last 30d: 18-32-0 (-13.5u)
CIN -1.5-110
1.5u
It’s October, time for Becht to turn into a 🎃
Stuck 🚨
Last 30d: 44-52-2 (-0.6u)
CIN -1-110
0.5u
Iowa State vs. Cincinnati Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Iowa State vs. Cincinnati Public Betting Percentages
Betting Trends
- Cincinnati are 3-1 in their last 5 games.
- Cincinnati are 3-1 in their last 5 games against the spread
- Cincinnati are 1-0 in their road games against the spread
- The totals have gone OVER in 3 of Cincinnati' last 4 games
- The totals have gone OVER in 2 of Cincinnati' 2 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 3-1 | 1-1 | 1-0 | 0-1 | 2-0 |
| 3-2 | 2-1 | 0-1 | 2-2 | 1-0 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 3-1 | 2-0 | 1-0 | 1-0 | 1-1 |
| 2-3 | 2-1 | 0-1 | 2-2 | 0-1 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 3-1 | N/A | N/A | 1-0 | 1-1 |
| 5-0 | N/A | N/A | 4-0 | 1-0 |
Last 5 Matchups
Team Stats
1176
YDS
1152
84/127
Comps/Atts
80/116
9.26
YPA
9.93
7/2
TDs/INTs
12/1
8/59
Sacks/Yards
1/11
20/26 76.9%
Redzone
17/17 100%
31/63 0%
3rd Down
14/37 0%
5/5 0%
4th Down
6/6 0%
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Penalties/Yards
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Iowa State vs. Cincinnati Odds Comparison
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Iowa State at Cincinnati Team Totals
MatchupOverUnder | ||
|---|---|---|
Iowa State 5-0 | N/A | N/A |
Cincinnati 3-1 | N/A | N/A |