Orioles vs. Guardians Odds & Betting Predictions - July 23, 2025

Orioles at Guardians

10:40 pm • CLEG
2 - 3
Starting Pitchers
pitcherteameraw-l
Slade Cecconi logoS.CecconiCleveland Guardians logo4.307-7
Zach Eflin logoZ.EflinBaltimore Orioles logo5.936-5

Orioles at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Orioles
0-0
-1.5
+1.5-191
o8.5-117
+110
Guardians
1-2
u8.5
-1.5+155
u8.5-103
-130
location pinWednesday 10:40 p.m.
July 23, 2025
Progressive FieldCleveland
Orioles vs. Guardians Expert Picks
Boomer Betz
Boomer Betz
Last 30d: 219-216-10 (+6.2u)
BAL +144 (Live)
1u
Sir Lockselot
Sir Lockselot
Last 30d: 22-73-0 (-60.7u)
BAL +110
2u
🔑 Orioles ML +110 (FanDuel) 2u Sharp fade angle: 78% of bets & 82% of ML money showing on Guardians, yet line movement has held steady and even ticked toward Baltimore in spots – a classic sign of sharp money backing the O’s. Pitching edge: Zach Eflin’s overall ERA (5.95) hides the fact that he’s posted a much stronger 3.41 ERA over his last 3 starts. Baltimore’s lineup has been heating up with Gunnar Henderson and Ryan O’Hearn combining for 4 HRs over the last week. Contrarian underdog with recent offensive surge and positive steam signals.
Al’s Analytics
Al’s Analytics
Last 30d: 0-0-0 (+0.0u)
Under 8.5-105
0.95u
95% of the money is on the Over…. We have some beautiful systems that aline to help us fade the public here Bad Teams Won Last Game and Game 3 56-15-2 (78.87%) 49.19% ROI 42-11 (79.2%) in 2025 Orioles Road Dog Series Closer 49-24-6 (67.1%) 26.01% ROI 13-3 (81.2%) in 2025 Guardians Home Under’s After Win After ASB 72-37-3 (66.1%) 25.41% ROI
Scott Rickenbach
Scott Rickenbach
Last 30d: 128-91-0 (+21.5u)
Over 8.5-118
1u
Lines at Lunch
Lines at Lunch
Last 30d: 92-101-6 (-20.6u)
G.Henderson o1.5 Total Bases+100
1u
Ryan Sura
Ryan Sura
Last 30d: 63-80-1 (-22.0u)
G.Henderson o1.5 Total Bases+100
1u
Sandy Plashkes
Sandy Plashkes
Last 30d: 114-132-6 (-19.1u)
G.Henderson o1.5 Total Bases+100
1u
Lines at Lunch
Lines at Lunch
Last 30d: 92-101-6 (-20.6u)
BAL +108
0.93u
Brian Bitler
Brian Bitler
Last 30d: 96-87-2 (+13.6u)
BAL +110
3u
CeeJ Sports
CeeJ Sports
Last 30d: 13-7-0 (+4.2u)
CLE -124
0.81u
Eflin is on the mound for the Orioles, and he has struggled vs lefties, which is a problem for him with this CLE lineup stacked with lefties. The CLE offense has come alive since the All-Star break, scoring 40 runs in their last 5 games. They are 4-1 since the break and have taken the first 2 games of this series, scoring 16 runs. Efflin's last 3 starts, the Orioles have lost by a combined 27-4. In those 3 games, he gave up 7,6,4 earned runs and allowed 12,10, and 5 hits. AKA, he is trash. Break out the brooms in Cleveland.
Matt DiLeo
Matt DiLeo
Last 30d: 54-40-1 (+4.7u)
Z.Eflin o14.5 Outs-135
0.74u

Orioles vs. Guardians Previews & Analysis

  • Orioles vs. Guardians: System Points to Under article feature image

    Orioles vs. Guardians: System Points to Under

    Action Network Staff
    Jul 23, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Orioles vs. Guardians Public Betting Percentages

Away Logo

Orioles

Public

25%

Bets%

75%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
86-7639-4247-3433-3651-38
Orioles
78-8437-4441-4025-4151-42

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
69-87-637-41-332-46-334-34-134-50-5
Orioles
65-92-534-44-331-48-231-32-332-59-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
88-7445-3643-3844-2543-46
Orioles
75-8739-4236-4532-3440-53

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jul 22ndBALW 6-3-1.5 WO 8CLE -161
Jul 21stBALW 10-5-1.5 WO 8.5CLE -143
Jul 20thATHW 8-2+1.5 WO 7.5CLE -106
Jul 19thATHL 2-8-1.5 LO 9ATH -134
Jul 18thATHW 8-6-1.5 WO 8CLE -134

Guardians vs. Orioles Injury Updates

Guardians Injuries

    Orioles Injuries

    • Grayson Rodriguez
      SP

      Rodriguez is out with elbow

      Out

    • Pedro Leon
      RF

      Leon is out with knee

      Out

    Orioles vs. Guardians Box Score
    Orioles Player Stats
    Projected
    PITCHERPCIPKER
    Zach Eflin logoRZ.Eflin, P84552
    Andrew Kittredge logoRA.Kittredge, P10100
    Yennier Cano logoRY.Cano, P13100
    Colin Selby logoRC.Selby, P23111
    HITTERSH-ABRHRRBI
    Jackson Holliday logo1J.Holliday, DH1-3111
    Jordan Westburg logo2J.Westburg, 2B1-4100
    Gunnar Henderson logo3G.Henderson, SS0-4000
    Ryan O'Hearn logo4R.O'Hearn, 1B1-3001
    Ramon Laureano logo5R.Laureano, RF1-4000
    Colton Cowser logo6C.Cowser, LF0-3000
    Ramon Urias logo7R.Urias, 3B0-1000
    Cedric Mullins logo8C.Mullins, CF1-3000
    Jacob Stallings logo9J.Stallings, C0-2000
    Dylan Carlson logo9D.Carlson, PH0-1000
    Alex Jackson logo9A.Jackson, C0-0000
    Guardians Player Stats
    Projected
    PITCHERPCIPKER
    Slade Cecconi logoRS.Cecconi, P85622
    Nic Enright logoRN.Enright, P12110
    Hunter Gaddis logoRH.Gaddis, P15110
    Emmanuel Clase logoRE.Clase, P12120
    HITTERSH-ABRHRRBI
    Steven Kwan logo1S.Kwan, LF1-3101
    Angel Martinez logo2A.Martinez, CF0-3000
    Jose Ramirez logo3J.Ramirez, 3B1-4100
    Kyle Manzardo logo4K.Manzardo, DH1-3002
    Carlos Santana logo5C.Santana, 1B0-3000
    Nolan Jones logo6N.Jones, RF0-3000
    Daniel Schneemann logo7D.Schneemann, 2B0-3000
    Brayan Rocchio logo8B.Rocchio, SS0-3000
    Bo Naylor logo9B.Naylor, C1-3100
    Austin Hedges logo9A.Hedges, C0-0000

    Orioles vs. Guardians Odds Comparison

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    Orioles at Guardians Team Totals

    MatchupOverUnder
    Orioles
    0-0
    o3.5-150
    u3.5+115
    Guardians
    1-2
    o4.5+104
    u4.5-132