Orioles vs. Guardians Odds & Betting Predictions - July 22, 2025
Orioles at Guardians
10:40 pm • CLEGStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 3.21 | 5-3 | ||
![]() | 6.24 | 1-7 |
Orioles at Guardians Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Orioles 0-0 | +1.5 | +1.5-162 | o8-108 | +135 |
Guardians 1-2 | u8 | -1.5+134 | u8-111 | -161 |

Progressive FieldCleveland
Orioles vs. Guardians Expert Picks
The Propfessor
Last 30d: 40-52-0 (+4.8u)
S.Kwan o1.5 Hits + Runs + RBIs-130
1u
Austin Pendergrass
Last 30d: 50-48-1 (+0.5u)
CLE -152
0.33u
Top Shelf Action 🥃
Last 30d: 193-180-1 (-7.7u)
Under 8-104
1.04u
Flat Favorites at Home (***)
Overall: 503-346-38,59% (ROI:15%)
Season:10-8-1,56% (ROI:5%)
Blowing In Ballparks (***)
Overall: 865-541-72,62% (ROI:18%)
Season:35-21-1,63% (ROI:19%)
Picks Office
Last 30d: 117-94-4 (+16.1u)
Under 8.5-115
1u
Follow @PicksOffice on X.
Brian Bitler
Last 30d: 75-74-2 (-7.0u)
BAL +125
3u
Capper Central
Last 30d: 84-68-0 (+2.3u)
CLE -135
1u
Orioles vs. Guardians Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Orioles vs. Guardians Public Betting Percentages
Betting Trends
- Guardians are 3-2 in their last 5 games.
- Guardians are 1-4 in their last 5 games against the spread
- Guardians are 47-34 in their road games against the spread
- The totals have gone OVER in 2 of Guardians' last 5 games
- The totals have gone OVER in 37 of Guardians' 81 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Orioles Injury Updates

Guardians Injuries
- Ben LivelySP
Lively is out with elbow
Out
- John MeansSP
Means is out with elbow
Out

Orioles Injuries
- Grayson RodriguezSP
Rodriguez is out with elbow
Out
Orioles vs. Guardians Box Score
Orioles Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 73 | 4.1 | 3 | 3 | |
![]() | 6 | 0.2 | 1 | 0 | |
![]() | 33 | 1 | 2 | 2 | |
![]() | 17 | 1 | 0 | 1 | |
![]() | 14 | 1 | 0 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 1-4 | 0 | 0 | 1 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 1 | 1 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-4 | 1 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-1 | 1 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 1-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
Guardians Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 95 | 5 | 5 | 1 | |
![]() | 23 | 1.2 | 2 | 1 | |
![]() | 8 | 0 | 0 | 1 | |
![]() | 31 | 1.1 | 1 | 0 | |
![]() | 13 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-5 | 0 | 0 | 0 |
![]() | 3-5 | 1 | 0 | 1 |
![]() | 1-2 | 1 | 1 | 1 |
![]() | 1-3 | 0 | 0 | 2 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-3 | 1 | 0 | 0 |
![]() | 1-2 | 1 | 0 | 0 |
![]() | 1-3 | 1 | 0 | 2 |
![]() | 0-2 | 1 | 0 | 0 |
Orioles vs. Guardians Odds Comparison
Could not load odds
Orioles at Guardians Team Totals
MatchupOverUnder | ||
|---|---|---|
Orioles 0-0 | o3.5-109 | u3.5-119 |
Guardians 1-2 | o4.5+109 | u4.5-139 |
































