Athletics vs. Astros Odds & Betting Predictions - May 28, 2025

Athletics at Astros

6:10 pm • SCHN
3 - 5
Starting Pitchers
pitcherteameraw-l
Lance McCullers logoL.McCullersHouston Astros logo5.890-1
Luis Severino logoL.SeverinoAthletics logo3.891-4

Athletics at Astros Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Athletics
23-33
-1.5
+1.5-181
o8.5-101
+120
Astros
30-25
u8.5
-1.5+150
u8.5-120
-142
location pinWednesday 6:10 p.m.
May 28, 2025
Daikin ParkHouston
Athletics vs. Astros Expert Picks
Steak Friend
Steak Friend
Last 30d: 195-216-1 (-33.9u)
Under 8.5 (Live)-127
1u
Sir Lockselot
Sir Lockselot
Last 30d: 38-53-0 (+16.4u)
ATH +120
2u
🔑 A’s ML +120 (FanDuel) 2u Running it back here. Sharp money strong on this one, 80% of public in the Astros and I like fading the team that just went off the night before. Let’s ride
Hammering Hank
Hammering Hank
Last 30d: 13-15-1 (-5.6u)
ATH +125
2u
Grant Neiffer
Grant Neiffer
Last 30d: 34-133-4 (+18.5u)
B.Rooker o0.5 HR+475
0.5u
Player Prop Savant
Player Prop Savant
Last 30d: 34-34-0 (+1.8u)
HOU o4.5 Team Total+106
1.06u
Picks Office
Picks Office
Last 30d: 74-76-2 (-5.4u)
HOU -135
0.74u
Oakland’s spiral is real – lost 12 of 13, including a brutal 11-1 blowout yesterday. Astros red hot at home – 19-10 at Daikin Park, riding 3-game win streak. Altuve hitting .571 last 5 games, 4-hit night yesterday. Team leads MLB in May BA (.280) with 5 straight 11+ hit games. Severino owns a 4.96 ERA vs HOU in 10 career outings – vulnerable vs this lineup. Astros hitters see him well: Altuve .308, Bregman 3 doubles, Tucker homered. Meanwhile, McCullers is trending up – 8 Ks in last outing. Houston bullpen: 2nd in MLB ERA (2.71), 1.11 WHIP, all key arms rested. Oakland pen? 28th in ERA (5.96), wild 4.73 BB/9. Astros also top-10 in fielding%. Add in the Astros’ +54 run differential at home.
Sandy Plashkes
Sandy Plashkes
Last 30d: 104-116-7 (-14.9u)
ATH +110 (F5)
1.1u
Lines at Lunch
Lines at Lunch
Last 30d: 72-97-6 (-28.7u)
Under 8.5-119
1u
Capper Central
Capper Central
Last 30d: 122-106-5 (-1.7u)
HOU -127
1u

Athletics vs. Astros Previews & Analysis

  • Our 3 MLB Best Bets for Wednesday Night article feature image

    Our 3 MLB Best Bets for Wednesday Night

    Action Network Staff
    May 28, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Athletics vs. Astros Public Betting Percentages

Away Logo

Athletics

Public

18%

Bets%

82%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Astros
31-2418-1213-1217-1914-4
Athletics
26-3011-1715-136-1120-18

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Astros
22-31-212-1810-13-218-183-13-2
Athletics
29-23-418-1011-13-48-7-221-15-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Astros
30-2520-1010-1520-1610-8
Athletics
23-339-1914-148-914-24

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 28thATHW 11-1-1.5 WO 8HOU -245
May 25thSEAW 5-3+1.5 WU 8.5HOU +124
May 24thSEAW 2-1+1.5 WU 7HOU -108
May 24thSEAL 3-5+1.5 LU 8.5SEA -122
May 23rdSEAW 9-2+1.5 WO 8HOU +110

Athletics vs. Astros Injury Updates

Athletics Injuries

  • Luis Medina
    SP

    Medina is out with elbow

    Out

  • J.T. Ginn
    SP

    Ginn is out with elbow

    Out

  • Ken Waldichuk
    SP

    Waldichuk is out with elbow

    Out

  • Zack Gelof
    2B

    Gelof is out with hand

    Out

  • Brett Harris
    3B

    Harris is out with oblique

    Out

  • Brady Basso
    RP

    Basso is out with shoulder

    Out

  • Nick Kurtz
    1B

    Kurtz is out with hip

    Out

Astros Injuries

  • Taylor Trammell
    LF

    Trammell is out with calf

    Out

  • Cristian Javier
    SP

    Javier is out with elbow

    Out

  • Luis Garcia
    SP

    Garcia is out with elbow

    Out

  • Pedro Leon
    RF

    Leon is out with knee

    Out

  • J.P. France
    SP

    France is out with shoulder

    Out

  • Hayden Wesneski
    RP

    Wesneski is out with elbow

    Out

  • Spencer Arrighetti
    SP

    Arrighetti is out with thumb

    Out

Athletics vs. Astros Box Score
Athletics Player Stats
Projected
PITCHERPCIPKER
Luis Severino logoRL.Severino, P92641
Justin Sterner logoRJ.Sterner, P230.203
Grant Holman logoRG.Holman, P171.110
HITTERSH-ABRHRRBI
Lawrence Butler logo1L.Butler, RF0-4000
Jacob Wilson logo2J.Wilson, SS2-3212
Brent Rooker logo3B.Rooker, DH2-4001
Tyler Soderstrom logo4T.Soderstrom, LF0-4000
Miguel Andujar logo5M.Andujar, 3B0-4000
Shea Langeliers logo6S.Langeliers, C1-4000
CJ Alexander logo7C.Alexander, 1B0-3000
Max Schuemann logo7M.Schuemann, PH0-0000
Luis Urias logo8L.Urias, 2B1-3100
Denzel Clarke logo9D.Clarke, CF0-4000
Astros Player Stats
Projected
PITCHERPCIPKER
Lance McCullers logoRL.McCullers, P1026123
Shawn Dubin logoRS.Dubin, P27120
Bryan Abreu logoRB.Abreu, P11110
Josh Hader logoLJ.Hader, P22130
HITTERSH-ABRHRRBI
Jeremy Pena logo1J.Pena, SS1-4100
Isaac Paredes logo2I.Paredes, 3B0-2101
Jose Altuve logo3J.Altuve, LF0-4000
Chas McCormick logo3C.McCormick, LF0-0000
Christian Walker logo4C.Walker, 1B0-1100
Mauricio Dubon logo4M.Dubon, PH1-2000
Mauricio Dubon logo4M.Dubon, 1B1-2000
Mauricio Dubon logo4M.Dubon, 2B1-2000
Victor Caratini logo5V.Caratini, C2-4002
Victor Caratini logo5V.Caratini, 1B2-4002
Jake Meyers logo6J.Meyers, CF0-3000
Cam Smith logo7C.Smith, RF1-4001
Zach Dezenzo logo8Z.Dezenzo, DH2-3211
Brendan Rodgers logo9B.Rodgers, 2B0-2000
Yainer Diaz logo9Y.Diaz, PH0-2000
Yainer Diaz logo9Y.Diaz, C0-2000

Athletics vs. Astros Odds Comparison

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Athletics at Astros Team Totals

MatchupOverUnder
Athletics
23-33
o3.5-126
u3.5-102
Astros
30-25
o4.5+111
u4.5-141