Astros vs. Guardians Odds & Betting Predictions - June 7, 2025

Astros at Guardians

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Astros at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
35-28
-1.5
-1.5+152
o6.5-124
-112
Guardians
33-29
u7
+1.5-185
u6.5+102
-105
location pinSaturday 8:10 p.m.
June 07, 2025
Progressive FieldCleveland
Astros vs. Guardians Expert Picks
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 137-159-3 (-3.7u)
Under 6.5+105
1u
Capper Central
Capper Central
Last 30d: 118-81-3 (+23.9u)
CLE +100
1u
Allan Lem
Allan Lem
Last 30d: 32-34-0 (-6.0u)
G.Williams u5.5 Ks-104
0.5u
Tailing @The_Oddsmaker
Sean Koerner
Sean Koerner
Last 30d: 13-15-0 (-1.2u)
G.Williams u5.5 Ks-104
1.04u
Williams has been dealing lately, clearing this number in 5 of his last 6 starts. But this is a tougher spot to rack up strikeouts. The Astros are a challenging matchup — they have the 8th-lowest whiff rate in the league, swing at the first pitch more than any team, and make contact on pitches in the zone at the 2nd-highest rate. That combo makes it harder for pitchers to get into two-strike counts and harder to finish them off when they do. Williams leans on his sweeper as his top put-away pitch, but Houston is also 8th in whiff rate against sweepers — so they match up well with what he does best. His best K chances are the 4, 7, and 9 hitters, but I’m projecting he gets pulled before facing the 7 and 9 hitters a third time, which caps some of his upside. I have his most likely outcome at 5 Ks and project this closer to -150 to stay under.
Steak Friend
Steak Friend
Last 30d: 134-153-1 (-28.6u)
CLE -103
1.03u
YBK Picks.com
Last 30d: 32-26-4 (+6.1u)
CLE -105
2u
Ray  Monohan
Ray Monohan
Last 30d: 7-9-0 (-1.6u)
CLE -102
0.75u
Picks Office
Picks Office
Last 30d: 78-74-0 (+3.4u)
CLE +105
1u
Wind blowing in 9.2 MPH at Progressive favors the arms – helps suppress Houston’s bats. Astros cooling off: .270 wOBA & 68 wRC+ over last 7 days, both bottom 6 in MLB. Hunter Brown’s still elite but 2.51 road ERA is nearly a full run higher than at home – regression looming. Gavin Williams locked in – 2.30 ERA over last 5 starts. Guardians 4-2 in his home starts. Last outing: 6.2 scoreless, 1 hit vs Angels. Houston’s .253 AVG hiding inefficiency – just 4.03 runs/game (22nd MLB). Cleveland thrives in small-ball spots: bunts, sac flies, situational ABs. Ramírez is the X-factor – .330 AVG, 11 HRs, elite RISP bat. Guardians’ pen underrated, 3.82 ERA (15th) but clutch in close games. Day game + home underdog vibes = edge in motivation. Cleveland’s urgency > Houston’s pressure. Astros won 7 of 8 vs CLE? Payback time.
💰🦡 Jake
💰🦡 Jake
Last 30d: 85-77-5 (+7.6u)
HOU -1.5+150
1u
Sandy Plashkes
Sandy Plashkes
Last 30d: 105-109-7 (+0.0u)
CLE +104
1u

Astros vs. Guardians Previews & Analysis

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Astros vs. Guardians Public Betting Percentages

Away Logo

Astros

Public

66%

Bets%

34%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
30-3214-1516-1711-1119-20
Astros
34-2918-1616-1319-2415-4

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
26-33-312-16-114-17-212-1014-22-3
Astros
25-36-214-2011-16-221-223-14-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
33-2917-1216-1715-718-21
Astros
35-2822-1213-1624-1911-8

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jun 6thHOUL 2-4+1.5 LU 8HOU +110
Jun 5th@NYYL 0-4+1.5 LU 8.5NYY +225
Jun 4th@NYYW 4-0+1.5 WU 9CLE +164
Jun 3rd@NYYL 2-3+1.5 WU 8NYY +166
Jun 1stLAAW 4-2-1.5 WU 8CLE -210

Guardians vs. Astros Injury Updates

Guardians Injuries

  • Ben Lively
    P

    Lively is out with elbow

    Out

  • Shane Bieber
    P

    Bieber is out with elbow

    Out

  • John Means
    P

    Means is out with elbow

    Out

Astros Injuries

  • Taylor Trammell
    OF

    Trammell is out with calf

    Out

  • Cristian Javier
    P

    Javier is out with elbow

    Out

  • Luis Garcia
    P

    Garcia is out with elbow

    Out

  • Pedro Leon
    OF

    Leon is out with knee

    Out

  • J.P. France
    P

    France is out with shoulder

    Out

  • Hayden Wesneski
    P

    Wesneski is out with elbow

    Out

  • Spencer Arrighetti
    P

    Arrighetti is out with thumb

    Out

Astros vs. Guardians Box Score
Astros Player Stats
Projected
PITCHERPCIPKER
Hunter Brown logoRH.Brown, P20120
HITTERSH-ABRHRRBI
Jeremy Pena logo1J.Pena, SS0-1000
Isaac Paredes logo2I.Paredes, 3B0-1000
Jose Altuve logo3J.Altuve, LF0-1000
Christian Walker logo4C.Walker, 1B-
Victor Caratini logo5V.Caratini, DH-
Yainer Diaz logo6Y.Diaz, C-
Jake Meyers logo7J.Meyers, CF-
Mauricio Dubon logo8M.Dubon, RF-
Brendan Rodgers logo9B.Rodgers, 2B-
Guardians Player Stats
Projected
PITCHERPCIPKER
Gavin Williams logoRG.Williams, P13110
HITTERSH-ABRHRRBI
Steven Kwan logo1S.Kwan, LF1-1000
Angel Martinez logo2A.Martinez, CF0-1000
Jose Ramirez logo3J.Ramirez, DH0-0000
Kyle Manzardo logo4K.Manzardo, 1B0-1000
Daniel Schneemann logo5D.Schneemann, 2B0-1000
Gabriel Arias logo6G.Arias, SS-
Bo Naylor logo7B.Naylor, C-
Nolan Jones logo8N.Jones, RF-
Will Wilson logo9W.Wilson, 3B-

Astros vs. Guardians Odds Comparison

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Astros at Guardians Team Totals

MatchupOverUnder
Astros
35-28
N/A
N/A
Guardians
33-29
N/A
N/A