Astros vs. Guardians Odds & Betting Predictions - June 6, 2025

Astros at Guardians

11:10 pm • CLEG
4 - 2
Starting Pitchers
pitcherteameraw-l
Logan Allen logoL.AllenCleveland Guardians logo4.258-11
Colton Gordon logoC.GordonHouston Astros logo5.346-4

Astros at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
0-0
+1.5
-1.5+134
o8-102
-128
Guardians
1-2
u8.5
+1.5-163
u8-118
+110
location pinFriday 11:10 p.m.
June 06, 2025
Progressive FieldCleveland
Astros vs. Guardians Expert Picks
Capper Central
Capper Central
Last 30d: 94-56-1 (+24.5u)
HOU -121
1u
Bet Labs
Bet Labs
Last 30d: 22-14-0 (+5.9u)
Under 8.5-115
1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 107-133-6 (+25.7u)
Over 8.5+104
1u
Picks Office
Picks Office
Last 30d: 66-81-3 (-11.2u)
HOU -105
0.95u
Derek Carty
Derek Carty
Last 30d: 15-21-0 (-2.9u)
Jose Ramirez o0.5 Walks+260
1u
Jim Sannes
Jim Sannes
Last 30d: 14-49-0 (-17.2u)
C.Gordon o4.5 Ks+116
1.16u
Have him projected at 5.12. Won't go deep in games, but he doesn't walk batters, which increases his pitch efficiency, and he gets a boost from a Guardians team that has struggled with strikeouts against lefties this year.
Sean Zerillo
Sean Zerillo
Last 30d: 158-185-6 (-10.1u)
HOU -105 (F5)
0.25u
Small to -120
HOU +105
0.53u
Bet to -104

Astros vs. Guardians Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Astros vs. Guardians Public Betting Percentages

Away Logo

Astros

Public

52%

Bets%

48%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
86-7639-4247-3433-3651-38
Astros
82-8037-4445-3643-6039-18

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
69-87-637-41-332-46-334-34-134-50-5
Astros
72-83-736-43-236-40-545-56-225-27-5

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
88-7445-3643-3844-2543-46
Astros
87-7546-3541-4056-4731-26

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jun 5th@NYYL 0-4+1.5 LU 8.5NYY +225
Jun 4th@NYYW 4-0+1.5 WU 9CLE +164
Jun 3rd@NYYL 2-3+1.5 WU 8NYY +166
Jun 1stLAAW 4-2-1.5 WU 8CLE -210
May 31stLAAW 7-5-1.5 WO 8CLE -169

Guardians vs. Astros Injury Updates

Guardians Injuries

  • Edward Lively
    SP

    Lively is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

Astros Injuries

  • Pedro Leon
    RF

    Leon is out with knee

    Out

  • Hayden Wesneski
    RP

    Wesneski is out with elbow

    Out

Astros vs. Guardians Box Score
Astros Player Stats
Projected
PITCHERPCIPKER
Colton Gordon logoLC.Gordon, P75551
Shawn Dubin logoRS.Dubin, P140.201
Bryan King logoLB.King, P191.110
Bryan Abreu logoRB.Abreu, P14110
Josh Hader logoLJ.Hader, P12120
HITTERSH-ABRHRRBI
Jeremy Pena logo1J.Pena, SS3-5100
Isaac Paredes logo2I.Paredes, 3B1-2100
Jose Altuve logo3J.Altuve, DH2-5101
Christian Walker logo4C.Walker, 1B1-4002
Jacob Meyers logo5J.Meyers, CF1-4000
Victor Caratini logo6V.Caratini, C0-3000
Mauricio Dubon logo7M.Dubon, LF1-4000
Brendan Rodgers logo8B.Rodgers, 2B1-3111
Jacob Melton logo9J.Melton, RF0-4000
Guardians Player Stats
Projected
PITCHERPCIPKER
Logan Allen logoLL.Allen, P88624
Matthew Festa logoRM.Festa, P22100
Tim Herrin logoLT.Herrin, P12110
Nicholas Enright logoRN.Enright, P21110
HITTERSH-ABRHRRBI
Angel Martinez logo1A.Martinez, CF1-4000
David Fry logo2D.Fry, DH2-3111
Jose Ramirez logo3J.Ramirez, 3B1-4000
Carlos Santana logo4C.Santana, 1B0-4000
Daniel Schneemann logo5D.Schneemann, LF1-4100
Gabriel Arias logo6G.Arias, SS2-4000
Nolan Jones logo7N.Jones, RF1-2000
Jhonkensy Noel logo7J.Noel, PH0-1000
Jhonkensy Noel logo7J.Noel, RF0-1000
William Wilson logo8W.Wilson, 2B1-3001
Dominic Nunez logo9D.Nunez, C0-3000

Astros vs. Guardians Odds Comparison

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Astros at Guardians Team Totals

MatchupOverUnder
Astros
0-0
o4.5+115
u4.5-146
Guardians
1-2
o3.5-113
u3.5-115