Astros vs. Guardians Odds & Betting Predictions - June 6, 2025
Astros at Guardians
11:10 pm • CLEGStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 4.25 | 8-11 | ||
![]() | 5.34 | 6-4 |
Astros at Guardians Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Astros 0-0 | +1.5 | -1.5+134 | o8-102 | -128 |
Guardians 1-2 | u8.5 | +1.5-163 | u8-118 | +110 |

Progressive FieldCleveland
Astros vs. Guardians Expert Picks
Capper Central
Last 30d: 84-68-0 (+2.3u)
HOU -121
1u
Bet Labs
Last 30d: 18-20-0 (-0.7u)
Under 8.5-115
1u
💰🦡 Jake
Last 30d: 117-134-8 (+0.3u)
Over 8.5+104
1u
Picks Office
Last 30d: 117-94-4 (+16.1u)
HOU -105
0.95u
Derek Carty
Last 30d: 28-26-0 (+7.8u)
Jose Ramirez o0.5 Walks+260
1u
Payoff Pitch: https://myaction.app/X5dMrBQZYTb
Jim Sannes
Last 30d: 19-55-0 (-18.2u)
C.Gordon o4.5 Ks+116
1.16u
Have him projected at 5.12. Won't go deep in games, but he doesn't walk batters, which increases his pitch efficiency, and he gets a boost from a Guardians team that has struggled with strikeouts against lefties this year.

Sean Zerillo
Last 30d: 98-117-5 (+5.2u)
HOU -105 (F5)
0.25u
Small to -120
HOU +105
0.53u
Bet to -104
Astros vs. Guardians Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Astros vs. Guardians Public Betting Percentages
Betting Trends
- Guardians are 3-2 in their last 5 games.
- Guardians are 1-4 in their last 5 games against the spread
- Guardians are 47-34 in their road games against the spread
- The totals have gone OVER in 2 of Guardians' last 5 games
- The totals have gone OVER in 37 of Guardians' 81 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Astros Injury Updates

Guardians Injuries
- Ben LivelySP
Lively is out with elbow
Out
- John MeansSP
Means is out with elbow
Out

Astros Injuries
- Pedro LeonRF
Leon is out with knee
Out
- Hayden WesneskiRP
Wesneski is out with elbow
Out
Astros vs. Guardians Box Score
Astros Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 75 | 5 | 5 | 1 | |
![]() | 14 | 0.2 | 0 | 1 | |
![]() | 19 | 1.1 | 1 | 0 | |
![]() | 14 | 1 | 1 | 0 | |
![]() | 12 | 1 | 2 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 3-5 | 1 | 0 | 0 |
![]() | 1-2 | 1 | 0 | 0 |
![]() | 2-5 | 1 | 0 | 1 |
![]() | 1-4 | 0 | 0 | 2 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-3 | 1 | 1 | 1 |
![]() | 0-4 | 0 | 0 | 0 |
Guardians Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 88 | 6 | 2 | 4 | |
![]() | 22 | 1 | 0 | 0 | |
![]() | 12 | 1 | 1 | 0 | |
![]() | 21 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-3 | 1 | 1 | 1 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 1-2 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 1 |
![]() | 0-3 | 0 | 0 | 0 |
Astros vs. Guardians Odds Comparison
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Astros at Guardians Team Totals
MatchupOverUnder | ||
|---|---|---|
Astros 0-0 | o4.5+115 | u4.5-146 |
Guardians 1-2 | o3.5-113 | u3.5-115 |





























