Astros vs. Guardians Odds & Betting Predictions - June 6, 2025

Astros at Guardians

11:10 pm • CLEG

Houston Astros

35-28

4 - 2

Cleveland Guardians

33-29

pitcher		team	era	w-l
L.Allen			4.42	3-4
C.Gordon			5.11	1-1

MatchupOpenSpreadTotalMoneyline
Astros 35-28	+1.5	-1.5+134	o8-102	-128
Guardians 33-29	u8.5	+1.5-163	u8-118	+110

Friday 11:10 p.m.

June 06, 2025

Progressive FieldCleveland

HOU -121

Under 8.5-115

Over 8.5+104

HOU -105

0.95u

Jose Ramirez o0.5 Walks+260

Payoff Pitch: https://myaction.app/X5dMrBQZYTb

C.Gordon o4.5 Ks+116

1.16u

Have him projected at 5.12. Won't go deep in games, but he doesn't walk batters, which increases his pitch efficiency, and he gets a boost from a Guardians team that has struggled with strikeouts against lefties this year.

HOU -105 (F5)

0.25u

Small to -120

HOU +105

0.53u

Bet to -104

Astros vs Guardians: Target This Side of Total
Action Network Staff•
Jun 6, 2025 UTC
+630, +875 Home Run Picks Worth Betting
Action AI•
Jun 6, 2025 UTC

See more MLB Coverage

No props found

MLB Public Betting

Guardians are 2-3 in their last 5 games.
Guardians are 3-2 in their last 5 games against the spread
Guardians are 16-17 in their road games against the spread
The totals have gone OVER in 0 of Guardians' last 5 games
The totals have gone OVER in 12 of Guardians' 29 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	30-32	14-15	16-17	11-11	19-20
Astros	34-29	18-16	16-13	19-24	15-4

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	26-33-3	12-16-1	14-17-2	12-10	14-22-3
Astros	25-36-2	14-20	11-16-2	21-22	3-14-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	33-29	17-12	16-17	15-7	18-21
Astros	35-28	22-12	13-16	24-19	11-8

date	opponent	score	spread	over/under	moneyline
Jun 5th	@NYY	L 0-4	+1.5 L	U 8.5	NYY +225
Jun 4th	@NYY	W 4-0	+1.5 W	U 9	CLE +164
Jun 3rd	@NYY	L 2-3	+1.5 W	U 8	NYY +166
Jun 1st	LAA	W 4-2	-1.5 W	U 8	CLE -210
May 31st	LAA	W 7-5	-1.5 W	O 8	CLE -169

Ben Lively
P
Lively is out with elbow
Out
Shane Bieber
P
Bieber is out with elbow
Out
John Means
P
Means is out with elbow
Out

Taylor Trammell
OF
Trammell is out with calf
Out
Cristian Javier
P
Javier is out with elbow
Out
Luis Garcia
P
Garcia is out with elbow
Out
Pedro Leon
OF
Leon is out with knee
Out
J.P. France
P
France is out with shoulder
Out
Hayden Wesneski
P
Wesneski is out with elbow
Out
Spencer Arrighetti
P
Arrighetti is out with thumb
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
LC.Gordon, P	75	5	5	1
RS.Dubin, P	14	0.2	0	1
LB.King, P	19	1.1	1	0
RB.Abreu, P	14	1	1	0
LJ.Hader, P	12	1	2	0

HITTERS	H-AB	R	HR	RBI
1J.Pena, SS	3-5	1	0	0
2I.Paredes, 3B	1-2	1	0	0
3J.Altuve, DH	2-5	1	0	1
4C.Walker, 1B	1-4	0	0	2
5J.Meyers, CF	1-4	0	0	0
6V.Caratini, C	0-3	0	0	0
7M.Dubon, LF	1-4	0	0	0
8B.Rodgers, 2B	1-3	1	1	1
9J.Melton, RF	0-4	0	0	0

PITCHER	PC	IP	K	ER
LL.Allen, P	88	6	2	4
RM.Festa, P	22	1	0	0
LT.Herrin, P	12	1	1	0
RN.Enright, P	21	1	1	0

HITTERS	H-AB	R	HR	RBI
1A.Martinez, CF	1-4	0	0	0
2D.Fry, DH	2-3	1	1	1
3J.Ramirez, 3B	1-4	0	0	0
4C.Santana, 1B	0-4	0	0	0
5D.Schneemann, LF	1-4	1	0	0
6G.Arias, SS	2-4	0	0	0
7N.Jones, RF	1-2	0	0	0
7J.Noel, PH	0-1	0	0	0
7J.Noel, RF	0-1	0	0	0
8W.Wilson, 2B	1-3	0	0	1
9D.Nunez, C	0-3	0	0	0